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Volumn 73, Issue 1, 2008, Pages 1-11

Alternative translation initiation of human regulators of G-protein signaling-2 yields a set of functionally distinct proteins

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE INHIBITOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; METHIONINE DERIVATIVE; RGS2 PROTEIN;

EID: 37349018834     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.036285     Document Type: Article
Times cited : (31)

References (41)
  • 1
    • 0030576518 scopus 로고    scopus 로고
    • GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits
    • Berman DM, Wilkie TM, and Gilman AG (1996) GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits. Cell 86:445-452.
    • (1996) Cell , vol.86 , pp. 445-452
    • Berman, D.M.1    Wilkie, T.M.2    Gilman, A.G.3
  • 2
    • 2442717874 scopus 로고    scopus 로고
    • RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11α signaling
    • Bernstein LS, Ramineni S, Hague C, Cladman W, Chidiac P, Levey AI, and Hepler JR (2004) RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11α signaling. J Biol Chem 279:21248-21256.
    • (2004) J Biol Chem , vol.279 , pp. 21248-21256
    • Bernstein, L.S.1    Ramineni, S.2    Hague, C.3    Cladman, W.4    Chidiac, P.5    Levey, A.I.6    Hepler, J.R.7
  • 3
    • 33947371974 scopus 로고    scopus 로고
    • N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells
    • Bodenstein J, Sunahara RK, and Neubig RR (2007) N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells. Mol Pharmacol 71:1040-1050.
    • (2007) Mol Pharmacol , vol.71 , pp. 1040-1050
    • Bodenstein, J.1    Sunahara, R.K.2    Neubig, R.R.3
  • 4
    • 0033869876 scopus 로고    scopus 로고
    • Translational control of C/EBPalpha and C/EBPbeta isoform expression
    • Calkhoven CF, Muller C, and Leutz A (2000) Translational control of C/EBPalpha and C/EBPbeta isoform expression. Genes Dev 14:1920-1932.
    • (2000) Genes Dev , vol.14 , pp. 1920-1932
    • Calkhoven, C.F.1    Muller, C.2    Leutz, A.3
  • 5
    • 0042664189 scopus 로고    scopus 로고
    • Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein γ-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants
    • Chatterjee TK, Liu Z, and Fisher RA (2003) Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein γ-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants. J Biol Chem 278:30261-30271.
    • (2003) J Biol Chem , vol.278 , pp. 30261-30271
    • Chatterjee, T.K.1    Liu, Z.2    Fisher, R.A.3
  • 6
    • 0033638967 scopus 로고    scopus 로고
    • Identification and characterization of a novel cell cycle-regulated internal ribosome entry site
    • Cornelis S, Bruynooghe Y, Denecker G, Van Huffel S, Tinton S, and Beyaert R (2000) Identification and characterization of a novel cell cycle-regulated internal ribosome entry site. Mol Cell 5:597-605.
    • (2000) Mol Cell , vol.5 , pp. 597-605
    • Cornelis, S.1    Bruynooghe, Y.2    Denecker, G.3    Van Huffel, S.4    Tinton, S.5    Beyaert, R.6
  • 7
    • 0034725661 scopus 로고    scopus 로고
    • RGS4 is arginylated and degraded by the N-end rule pathway in vitro
    • Davydov IV and Varshavsky A (2000) RGS4 is arginylated and degraded by the N-end rule pathway in vitro. J Biol Chem 275:22931-22941.
    • (2000) J Biol Chem , vol.275 , pp. 22931-22941
    • Davydov, I.V.1    Varshavsky, A.2
  • 9
    • 0035724427 scopus 로고    scopus 로고
    • Identification and characterization of alternatively spliced murine Rgs11 isoforms: Genomic structure and gene analysis
    • Giudice A, Gould JA, Freeman KB, Rastan S, Hertzog P, Kola I, and Iannello RC (2001) Identification and characterization of alternatively spliced murine Rgs11 isoforms: genomic structure and gene analysis. Cytogenet Cell Genet 94:216-224.
    • (2001) Cytogenet Cell Genet , vol.94 , pp. 216-224
    • Giudice, A.1    Gould, J.A.2    Freeman, K.B.3    Rastan, S.4    Hertzog, P.5    Kola, I.6    Iannello, R.C.7
  • 10
    • 0031782937 scopus 로고    scopus 로고
    • Molecular characterization of human and rat RGS 9L, a novel splice variant enriched in dopamine target regions, and chromosomal localization of the RGS 9 gene
    • Granneman JG, Zhai Y, Zhu Z, Bannon MJ, Burchett SA, Schmidt CJ, Andrade R, and Cooper J (1998) Molecular characterization of human and rat RGS 9L, a novel splice variant enriched in dopamine target regions, and chromosomal localization of the RGS 9 gene. Mol Pharmacol 54:687-694.
    • (1998) Mol Pharmacol , vol.54 , pp. 687-694
    • Granneman, J.G.1    Zhai, Y.2    Zhu, Z.3    Bannon, M.J.4    Burchett, S.A.5    Schmidt, C.J.6    Andrade, R.7    Cooper, J.8
  • 11
    • 22844433094 scopus 로고    scopus 로고
    • Selective inhibition of α1A-adrenergic receptor signaling by RGS2 association with the receptor third intracellular loop
    • Hague C, Bernstein LS, Ramineni S, Chen Z, Minneman KP, and Hepler JR (2005) Selective inhibition of α1A-adrenergic receptor signaling by RGS2 association with the receptor third intracellular loop. J Biol Chem 280:27289-27295.
    • (2005) J Biol Chem , vol.280 , pp. 27289-27295
    • Hague, C.1    Bernstein, L.S.2    Ramineni, S.3    Chen, Z.4    Minneman, K.P.5    Hepler, J.R.6
  • 12
    • 0037019821 scopus 로고    scopus 로고
    • Structure, chromosomal localization and expression of the mouse regulator of G-protein signaling 10 gene (mRGS10)
    • Haller C, Fillatreau S, Hoffmann R, and Agenes F (2002) Structure, chromosomal localization and expression of the mouse regulator of G-protein signaling 10 gene (mRGS10). Gene 297:39-49.
    • (2002) Gene , vol.297 , pp. 39-49
    • Haller, C.1    Fillatreau, S.2    Hoffmann, R.3    Agenes, F.4
  • 13
    • 0033838141 scopus 로고    scopus 로고
    • Termination and peptide release at the upstream open reading frame are required for downstream translation on synthetic shunt-competent mRNA leaders
    • Hemmings-Mieszczak M, Hohn T, and Preiss T (2000) Termination and peptide release at the upstream open reading frame are required for downstream translation on synthetic shunt-competent mRNA leaders. Mol Cell Biol 20:6212-6223.
    • (2000) Mol Cell Biol , vol.20 , pp. 6212-6223
    • Hemmings-Mieszczak, M.1    Hohn, T.2    Preiss, T.3
  • 15
    • 4344678297 scopus 로고    scopus 로고
    • RGS2-mediated regulation of Gqalpha
    • Heximer SP (2004) RGS2-mediated regulation of Gqalpha. Methods Enzymol 390:65-82.
    • (2004) Methods Enzymol , vol.390 , pp. 65-82
    • Heximer, S.P.1
  • 16
    • 33947544164 scopus 로고    scopus 로고
    • RGS proteins: Swiss army knives in seven-transmembrane domain receptor signaling networks
    • Heximer SP and Blumer KJ (2007) RGS proteins: Swiss army knives in seven-transmembrane domain receptor signaling networks. Sci STKE 2007(370):pe2.
    • (2007) Sci STKE 2007(370):pe2
    • Heximer, S.P.1    Blumer, K.J.2
  • 17
    • 0035957996 scopus 로고    scopus 로고
    • Mechanisms governing subcellular localization and function of human RGS2
    • Heximer SP, Lim H, Bernard JL, and Blumer KJ (2001) Mechanisms governing subcellular localization and function of human RGS2. J Biol Chem 276:14195-14203.
    • (2001) J Biol Chem , vol.276 , pp. 14195-14203
    • Heximer, S.P.1    Lim, H.2    Bernard, J.L.3    Blumer, K.J.4
  • 19
    • 27144557281 scopus 로고    scopus 로고
    • The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators
    • Hu RG, Sheng J, Qi X, Xu Z, Takahashi TT, and Varshavsky A (2005) The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators. Nature 437:981-986.
    • (2005) Nature , vol.437 , pp. 981-986
    • Hu, R.G.1    Sheng, J.2    Qi, X.3    Xu, Z.4    Takahashi, T.T.5    Varshavsky, A.6
  • 21
    • 0036129270 scopus 로고    scopus 로고
    • RGS2: A multifunctional regulator of G-protein signaling
    • Kehrl JH and Sinnarajah S (2002) RGS2: a multifunctional regulator of G-protein signaling. Int J Biochem Cell Biol 34:432-438.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 432-438
    • Kehrl, J.H.1    Sinnarajah, S.2
  • 22
    • 0036015208 scopus 로고    scopus 로고
    • Additional 5′ exons in the RGS3 locus generate multiple mRNA transcripts, one of which accounts for the origin of human PDZ-RGS3
    • Kehrl JH, Srikumar D, Harrison K, Wilson GL, and Shi CS (2002) Additional 5′ exons in the RGS3 locus generate multiple mRNA transcripts, one of which accounts for the origin of human PDZ-RGS3. Genomics 79:860-868.
    • (2002) Genomics , vol.79 , pp. 860-868
    • Kehrl, J.H.1    Srikumar, D.2    Harrison, K.3    Wilson, G.L.4    Shi, C.S.5
  • 23
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
    • Kozak M (1986) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44:283-292.
    • (1986) Cell , vol.44 , pp. 283-292
    • Kozak, M.1
  • 24
    • 0026342613 scopus 로고
    • An analysis of vertebrate mRNA sequences: Intimations of translational control
    • Kozak M (1991) An analysis of vertebrate mRNA sequences: intimations of translational control. J Cell Biol 115:887-903.
    • (1991) J Cell Biol , vol.115 , pp. 887-903
    • Kozak, M.1
  • 27
    • 0031452563 scopus 로고    scopus 로고
    • Alternative translation of the proto-oncogene c-myc by an internal ribosome entry site
    • Nanbru C, Lafon I, Audigier S, Gensac MC, Vagner S, Huez G, and Prats AC (1997) Alternative translation of the proto-oncogene c-myc by an internal ribosome entry site. J Biol Chem 272:32061-32066.
    • (1997) J Biol Chem , vol.272 , pp. 32061-32066
    • Nanbru, C.1    Lafon, I.2    Audigier, S.3    Gensac, M.C.4    Vagner, S.5    Huez, G.6    Prats, A.C.7
  • 28
    • 0033783132 scopus 로고    scopus 로고
    • GTPase-activating proteins for heterotrimeric G proteins: Regulators of G protein signaling (RGS) and RGS-like proteins
    • Ross EM and Wilkie TM (2000) GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. Annu Rev Biochem 69:795-827.
    • (2000) Annu Rev Biochem , vol.69 , pp. 795-827
    • Ross, E.M.1    Wilkie, T.M.2
  • 30
    • 0041854353 scopus 로고    scopus 로고
    • Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions
    • Roy AA, Lemberg KE, and Chidiac P (2003) Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions. Mol Pharmacol 64:587-593.
    • (2003) Mol Pharmacol , vol.64 , pp. 587-593
    • Roy, A.A.1    Lemberg, K.E.2    Chidiac, P.3
  • 32
    • 0037162557 scopus 로고    scopus 로고
    • Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling
    • Saitoh O, Murata Y, Odagiri M, Itoh M, Itoh H, Misaka T, and Kubo Y (2002) Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling. Proc Natl Acad Sci U S A 99:10138-10143.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10138-10143
    • Saitoh, O.1    Murata, Y.2    Odagiri, M.3    Itoh, M.4    Itoh, H.5    Misaka, T.6    Kubo, Y.7
  • 33
    • 0037844848 scopus 로고    scopus 로고
    • Identification of RGS2 and type V adenylyl cyclase interaction sites
    • Salim S, Sinnarajah S, Kehrl JH, and Dessauer CW (2003) Identification of RGS2 and type V adenylyl cyclase interaction sites. J Biol Chem 278:15842-15849.
    • (2003) J Biol Chem , vol.278 , pp. 15842-15849
    • Salim, S.1    Sinnarajah, S.2    Kehrl, J.H.3    Dessauer, C.W.4
  • 37
    • 0029861143 scopus 로고    scopus 로고
    • The N-end rule: Functions, mysteries, uses
    • Varshavsky A (1996) The N-end rule: functions, mysteries, uses. Proc Natl Acad Sci U S A 93:12142-12149.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 12142-12149
    • Varshavsky, A.1
  • 39
    • 0029808079 scopus 로고    scopus 로고
    • RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits
    • Watson N, Linder ME, Druey KM, Kehrl JH, and Blumer KJ (1996) RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits. Nature 383:172-175.
    • (1996) Nature , vol.383 , pp. 172-175
    • Watson, N.1    Linder, M.E.2    Druey, K.M.3    Kehrl, J.H.4    Blumer, K.J.5
  • 41
    • 0033230684 scopus 로고    scopus 로고
    • Divergence of RGS proteins: Evidence for the existence of six mammalian RGS subfamilies
    • Zheng B, De Vries L, and Gist Farquhar M (1999) Divergence of RGS proteins: evidence for the existence of six mammalian RGS subfamilies. Trends Biochem Sci 24:411-414
    • (1999) Trends Biochem Sci , vol.24 , pp. 411-414
    • Zheng, B.1    De Vries, L.2    Gist Farquhar, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.