Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome

Journal of Hypertension

Volumn 29, Issue 11, 2011, Pages 2126-2137

  Gebhard, Simon ^a   Steil, Leif ^b   Peters, Barbara ^c   Gesell Salazar, Manuela ^b   Hammer, Elke ^b   Kuttler, Beate ^c   Clemetson, Kenneth J ^d   Scharf, Christian ^b,c   Peters, Jörg ^c   Völker, Uwe ^b   Rettig, Rainer ^c   Greinacher, Andreas ^a  

^a Institut fur Immunologie und Transfusionsmedizin   (Germany)

^b Interfakultäres Institut für Genetik und Funktionelle Genomforschung   (Germany)

^c UNIVERSITY OF GREIFSWALD   (Germany)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

angiotensin II; hypertension; platelets; proteome; rats

Indexed keywords

3 INDOLEMETHANOL; ANGIOTENSIN II; APOLIPOPROTEIN E; FIBRINOGEN; FILAMIN A; HEAT SHOCK PROTEIN 90; KHELLIN; PLECKSTRIN; TALIN; THROMBOPOIETIN RECEPTOR; THROMBOSPONDIN; THROMBOSPONDIN 1; TRANSGELIN; VINCULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; HYPERTENSION; MALE; MEGAKARYOPOIESIS; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; PROTEOMICS; RAT; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE;

EID: 80054104931     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0b013e32834b1991     Document Type: Article

References (29)

1. Ruggeri ZM. Platelets in atherothrombosis. Nat Med 2002; 8:1227-1234. (Pubitemid 35373553)
2. Chen J, Lopez JA. Interactions of platelets with subendothelium and endothelium. Microcirculation 2005; 12:235-246. (Pubitemid 40691821)
3. Gawaz M, Langer H, May AE. Platelets in inflammation and atherogenesis. J Clin Invest 2005; 115:3378-3384. (Pubitemid 43121822)
4. Langer HF, Bigalke B, Seizer P, Stellos K, Fateh-Moghadam S, Gawaz M. Interaction of platelets and inflammatory endothelium in the development and progression of coronary artery disease. Semin Thromb Hemost 2010; 36:131-138.
5. Schafer A, Bauersachs J. Endothelial dysfunction, impaired endogenous platelet inhibition and platelet activation in diabetes and atherosclerosis. Curr Vasc Pharmacol 2008; 6:52-60.
6. Koller A. Signaling pathways of mechanotransduction in arteriolar endothelium and smooth muscle cells in hypertension. Microcirculation 2002; 9:277-294. (Pubitemid 135685863)
7. Macaulay IC, Carr P, Gusnanto A, Ouwehand WH, Fitzgerald D, Watkins NA. Platelet genomics and proteomics in human health and disease. J Clin Invest 2005; 115:3370-3377. (Pubitemid 43121821)
8. Senzel L, Gnatenko DV, Bahou WF. The platelet proteome. Curr Opin Hematol 2009; 16:329-333.
9. Liumbruno G, D'Alessandro A, Grazzini G, Zolla L. Blood-related proteomics. J Proteomics 2010; 73:483-507.
10. Polkinghorne VR, Standeven KF, Schroeder V, Carter AM. Role of proteomic technologies in understanding risk of arterial thrombosis. Expert Rev Proteomics 2009; 6:539-550.
11. UnluM, Morgan ME, Minden JS. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis 1997; 18:2071-2077. (Pubitemid 27501267)
12. Thiele T, Steil L, Gebhard S, Scharf C, Hammer E, Brigulla M, et al. Profiling of alterations in platelet proteins during storage of platelet concentrates. Transfusion 2007; 47:1221-1233. (Pubitemid 46934314)
13. Kantachuvesiri S, Fleming S, Peters J, Peters B, Brooker G, Lammie AG, et al. Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease. J Biol Chem 2001; 276:36727-36733.
14. Peters B, Grisk O, Becher B, Wanka H, Kuttler B, Ludemann J, et al. Dose-dependent titration of prorenin and blood pressure in cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis. J Hypertens 2008; 26:102-109. (Pubitemid 350301935)
15. Grisk O, Kloting I, Exner J, Spiess S, Schmidt R, Junghans D, et al. Long-term arterial pressure in spontaneously hypertensive rats is set by the kidney. J Hypertens 2002; 20:131-138. (Pubitemid 34913412)
16. Brigulla M, Thiele T, Scharf C, Breitner-Ruddock S, Venz S, Volker U, Greinacher A. Proteomics as a tool for assessment of therapeutics in transfusion medicine: evaluation of prothrombin complex concentrates. Transfusion 2006; 46:377-385. (Pubitemid 43334090)
17. Eymann C, Dreisbach A, Albrecht D, Bernhardt J, Becher D, Gentner S, et al. A comprehensive proteome map of growing bacillus subtilis cells. Proteomics 2004; 4:2849-2876. (Pubitemid 39372373)
18. Handagama PJ, Feldman BF, Jain NC, Farver TB, Kono CS. Circulating proplatelets: isolation and quantitation in healthy rats and in rats with induced acute blood loss. Am J Vet Res 1987; 48:962-965.
19. Hobisch-Hagen P, Jelkmann W, Mayr A, Wiedermann FJ, Fries D, Herold M, et al. Low platelet count and elevated serum thrombopoietin after severe trauma. Eur J Haematol 2000; 64:157-163. (Pubitemid 30158047)
20. Rodgers KE, Xiong S, Steer R, diZerega GS. Effect of angiotensin ii on hematopoietic progenitor cell proliferation. Stem Cells 2000; 18:287-294. (Pubitemid 30602276)
21. Lande K, Os I, Kjeldsen SE, Westheim A, Hjermann I, Eide I, Gjesdal K. Increased platelet size and release reaction in essential hypertension. J Hypertens 1987; 5:401-406. (Pubitemid 17126232)
22. Nadar SK, Blann AD, Kamath S, Beevers DG, Lip GY. Platelet indexes in relation to target organ damage in high-risk hypertensive patients: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). J Am Coll Cardiol 2004; 44:415-422. (Pubitemid 38950604)
23. Nityanand S, Pande I, Bajpai VK, Singh L, Chandra M, Singh BN. Platelets in essential hypertension. Thromb Res 1993; 72:447-454. (Pubitemid 23345334)
24. Li YS, Haga JH, Chien S. Molecular basis of the effects of shear stress on vascular endothelial cells. J Biomech 2005; 38:1949-1971. (Pubitemid 41111740)
25. DielisAW,SmidM,SpronkHM,Hamulyak K, Kroon AA, tenCate H,deLeeuw PW. The prothrombotic paradox of hypertension: role of the renin-angiotensin and kallikrein-kinin systems. Hypertension 2005; 46:1236-1242. (Pubitemid 43189713)
26. Crabos M, Bertschin S, Buhler FR, Rogg H, Evequoz D, Eberhard M, Erne P. Identification of at1 receptors on human platelets and decreased angiotensin ii binding in hypertension. J Hypertens Suppl 1993; 11:S230-S231. (Pubitemid 24024783)
27. Larsson PT, Schwieler JH, Wallen NH. Platelet activation during angiotensin ii infusion in healthy volunteers. Blood Coagul Fibrinolysis 2000; 11:61-69. (Pubitemid 30090905)
28. Aoki S, Osada M, Kaneko M, Ozaki Y, Yatomi Y. Fluid shear stress enhances the sphingosine 1-phosphate responses in cell-cell interactions between platelets and endothelial cells. Biochem Biophys Res Commun 2007; 358:1054-1057. (Pubitemid 46828994)
29. Mrug M, Stopka T, Julian BA, Prchal JF, Prchal JT. Angiotensin ii stimulates proliferation of normal early erythroid progenitors. J Clin Invest 1997; 100:2310-2314. (Pubitemid 27500154)