-
1
-
-
0017115289
-
Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum
-
Yamasaki H: Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum. Acta Med Okayama 30: 1-20, 1976.
-
(1976)
Acta Med Okayama
, vol.30
, pp. 1-20
-
-
Yamasaki, H.1
-
2
-
-
55949101441
-
PH-dependent, stereoselective dimerization of sinomenine
-
Deng ZS, Zhao Y, He CC, Jin J, He YM and Li JX: pH-dependent, stereoselective dimerization of sinomenine. Org Lett 10: 3879-3882, 2008.
-
(2008)
Org Lett
, vol.10
, pp. 3879-3882
-
-
Deng, Z.S.1
Zhao, Y.2
He, C.C.3
Jin, J.4
He, Y.M.5
Li, J.X.6
-
3
-
-
52949088275
-
Sinomenine ameliorates arthritis via MMPs, TIMPs, and cytokines in rats
-
Zhou H, Wong YF, Wang J, Cai X and Liu L: Sinomenine ameliorates arthritis via MMPs, TIMPs, and cytokines in rats. Biochem Biophys Res Commun 376: 352-357, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 352-357
-
-
Zhou, H.1
Wong, Y.F.2
Wang, J.3
Cai, X.4
Liu, L.5
-
4
-
-
20344370314
-
Immunosuppressive effect of Sinomenine on ICAM-1 expression in rat renal allograft rejection
-
Dai YB, Huang X, Luo ZG, Li JF, Ou YG, Yang P and Qin JP: Immunosuppressive effect of Sinomenine on ICAM-1 expression in rat renal allograft rejection. Mod J Integr Tradit Chin West Med 12: 1358-1363, 2003.
-
(2003)
Mod J Integr Tradit Chin West Med
, vol.12
, pp. 1358-1363
-
-
Dai, Y.B.1
Huang, X.2
Luo, Z.G.3
Li, J.F.4
Ou, Y.G.5
Yang, P.6
Qin, J.P.7
-
5
-
-
20344387285
-
Effects of sinomenine on T lymphocyte subsets in rat renal allograft transplantation model
-
Yang P, Yang L and Luo Z: Effects of sinomenine on T lymphocyte subsets in rat renal allograft transplantation model. J Clin Urol 18: 620-622, 2003.
-
(2003)
J Clin Urol
, vol.18
, pp. 620-622
-
-
Yang, P.1
Yang, L.2
Luo, Z.3
-
6
-
-
39049140211
-
Effect of sinomenine on collagen-induced arthritis in mice
-
Feng H, Yamaki K, Takano H, Inoue K, Yanagisawa R and Yoshino S: Effect of sinomenine on collagen-induced arthritis in mice. Autoimmunity 40: 532-539, 2007.
-
(2007)
Autoimmunity
, vol.40
, pp. 532-539
-
-
Feng, H.1
Yamaki, K.2
Takano, H.3
Inoue, K.4
Yanagisawa, R.5
Yoshino, S.6
-
7
-
-
44949195816
-
T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis
-
Cohen RA, Bayliss G, Crispin JC, Kane-Wanger GF, Van Beek CA, Kyttaris VC, Avalos I, Yu CY, Tsokos GC and Stillman IE: T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis. Clin Immunol 128: 1-7, 2008.
-
(2008)
Clin Immunol
, vol.128
, pp. 1-7
-
-
Cohen, R.A.1
Bayliss, G.2
Crispin, J.C.3
Kane-Wanger, G.F.4
Van Beek, C.A.5
Kyttaris, V.C.6
Avalos, I.7
Yu, C.Y.8
Tsokos, G.C.9
Stillman, I.E.10
-
8
-
-
35948929764
-
Role of T cells and dendritic cells in glomerular immunopathology
-
Kurts C, Heymann F, Lukacs-Kornek V, Boor P and Floege J: Role of T cells and dendritic cells in glomerular immunopathology. Semin Immunopathol 29: 317-335, 2007.
-
(2007)
Semin Immunopathol
, vol.29
, pp. 317-335
-
-
Kurts, C.1
Heymann, F.2
Lukacs-Kornek, V.3
Boor, P.4
Floege, J.5
-
9
-
-
0036593175
-
Activation rules: The two-signal theories of immune activation
-
Baxter AG and Hodgkin PD: Activation rules: the two-signal theories of immune activation. Nat Rev Immunol 2: 439-446, 2002.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 439-446
-
-
Baxter, A.G.1
Hodgkin, P.D.2
-
10
-
-
54049104938
-
T-cell co-stimulatory pathways in autoimmunity
-
Goronzy JJ and Weyand CM: T-cell co-stimulatory pathways in autoimmunity. Arthritis Res Ther 10 (Suppl 1): S3, 2008.
-
(2008)
Arthritis Res Ther
, vol.10
, Issue.SUPPL. 1
-
-
Goronzy, J.J.1
Weyand, C.M.2
-
11
-
-
42649109659
-
Immuno-gene therapy approaches for cancer: From in vitro studies to clinical trials
-
Loisel-Meyer S, Foley R and Medin JA: Immuno-gene therapy approaches for cancer: from in vitro studies to clinical trials. Front Biosci 13: 3202-3214, 2008.
-
(2008)
Front Biosci
, vol.13
, pp. 3202-3214
-
-
Loisel-Meyer, S.1
Foley, R.2
Medin, J.A.3
-
12
-
-
20744432041
-
Tumor immunotherapy: Preclinical and clinical activity of anti-CTLA4 antibodies
-
Korman A, Yellin M and Keler T: Tumor immunotherapy: preclinical and clinical activity of anti-CTLA4 antibodies. Curr Opin Investig Drugs 6: 582-591, 2005.
-
(2005)
Curr Opin Investig Drugs
, vol.6
, pp. 582-591
-
-
Korman, A.1
Yellin, M.2
Keler, T.3
-
13
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
-
Nishimura H, Okazaki T, Tanaka Y, Nakatani K, Hara M, Matsumori A, Sasayama S, Mizoguchi A, Hiai H, Minato N and Honjo T: Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 291: 319-322, 2001.
-
(2001)
Science
, vol.291
, pp. 319-322
-
-
Nishimura, H.1
Okazaki, T.2
Tanaka, Y.3
Nakatani, K.4
Hara, M.5
Matsumori, A.6
Sasayama, S.7
Mizoguchi, A.8
Hiai, H.9
Minato, N.10
Honjo, T.11
-
14
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
Fife BT, Pauken KE, Eagar TN, Obu T, Wu J, Tang Q, Azuma M, Krummel MF and Bluestone JA: Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol 10: 1185-1192, 2009.
-
(2009)
Nat Immunol
, vol.10
, pp. 1185-1192
-
-
Fife, B.T.1
Pauken, K.E.2
Eagar, T.N.3
Obu, T.4
Wu, J.5
Tang, Q.6
Azuma, M.7
Krummel, M.F.8
Bluestone, J.A.9
-
15
-
-
3242677686
-
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells
-
Latchman YE, Liang SC, Wu Y, Chernova T, Sobel RA, Klemm M, Kuchroo VK, Freeman GJ and Sharpe AH: PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proc Natl Acad Sci USA 101: 10691-10696, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10691-10696
-
-
Latchman, Y.E.1
Liang, S.C.2
Wu, Y.3
Chernova, T.4
Sobel, R.A.5
Klemm, M.6
Kuchroo, V.K.7
Freeman, G.J.8
Sharpe, A.H.9
-
16
-
-
0032736029
-
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
-
Dong H, Zhu G, Tamada K and Chen L: B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med 5: 1365-1369, 1999.
-
(1999)
Nat Med
, vol.5
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Chen, L.4
-
17
-
-
85047690551
-
Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection
-
Subudhi SK, Zhou P, Yerian LM, Chin RK, Lo JC, Anders RA, Sun Y, Chen L, Wang Y, Alegre ML and Fu YX: Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection. J Clin Invest 113: 694-700, 2004.
-
(2004)
J Clin Invest
, vol.113
, pp. 694-700
-
-
Subudhi, S.K.1
Zhou, P.2
Yerian, L.M.3
Chin, R.K.4
Lo, J.C.5
Anders, R.A.6
Sun, Y.7
Chen, L.8
Wang, Y.9
Alegre, M.L.10
Fu, Y.X.11
-
18
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2[-Delta Delta C(T)] method
-
Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2[-Delta Delta C(T)] method. Methods 25: 402-408, 2001.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
19
-
-
33344454876
-
Expression of B7-H1 in inflammatory renal tubular epithelial cells
-
Chen Y, Zhang J, Li J, Zou L, Zhao T, Tang Y and Wu Y: Expression of B7-H1 in inflammatory renal tubular epithelial cells. Nephron Exp Nephrol 102: 81-92, 2006.
-
(2006)
Nephron Exp Nephrol
, vol.102
, pp. 81-92
-
-
Chen, Y.1
Zhang, J.2
Li, J.3
Zou, L.4
Zhao, T.5
Tang, Y.6
Wu, Y.7
-
20
-
-
67349086056
-
Immunoregulatory effects of sinomenine on the T-bet/GATA-3 ratio and Th1/Th2 cytokine balance in the treatment of mesangial proliferative nephritis
-
Cheng Y, Zhang J, Hou W, Wang D, Li F, Zhang Y and Yuan F: Immunoregulatory effects of sinomenine on the T-bet/GATA-3 ratio and Th1/Th2 cytokine balance in the treatment of mesangial proliferative nephritis. Int Immunopharmacol 9: 894-899, 2009.
-
(2009)
Int Immunopharmacol
, vol.9
, pp. 894-899
-
-
Cheng, Y.1
Zhang, J.2
Hou, W.3
Wang, D.4
Li, F.5
Zhang, Y.6
Yuan, F.7
-
21
-
-
53749092575
-
PD-1/PD-L1, PD-1/PD-L2, and other co-inhibitory signaling pathways in transplantation
-
del Rio ML, Buhler L, Gibbons C, Tian J and Rodriguez-Barbosa JI: PD-1/PD-L1, PD-1/PD-L2, and other co-inhibitory signaling pathways in transplantation. Transpl Int 21: 1015-1028, 2008.
-
(2008)
Transpl Int
, vol.21
, pp. 1015-1028
-
-
Del Rio, M.L.1
Buhler, L.2
Gibbons, C.3
Tian, J.4
Rodriguez-Barbosa, J.I.5
-
22
-
-
38849127548
-
Programmed death 1 ligand (PD-L) 1 and PD-L2 limit autoimmune kidney disease: Distinct roles
-
Menke J, Lucas JA, Zeller GC, Keir ME, Huang XR, Tsuboi N, Mayadas TN, Lan HY, Sharpe AH and Kelley VR: Programmed death 1 ligand (PD-L) 1 and PD-L2 limit autoimmune kidney disease: distinct roles. J Immunol 179: 7466-7477, 2007.
-
(2007)
J Immunol
, vol.179
, pp. 7466-7477
-
-
Menke, J.1
Lucas, J.A.2
Zeller, G.C.3
Keir, M.E.4
Huang, X.R.5
Tsuboi, N.6
Mayadas, T.N.7
Lan, H.Y.8
Sharpe, A.H.9
Kelley, V.R.10
-
23
-
-
0035869569
-
B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function
-
Tamura H, Dong H, Zhu G, Sica GL, Flies DB, Tamada K and Chen L: B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function. Blood 97: 1809-1816, 2001.
-
(2001)
Blood
, vol.97
, pp. 1809-1816
-
-
Tamura, H.1
Dong, H.2
Zhu, G.3
Sica, G.L.4
Flies, D.B.5
Tamada, K.6
Chen, L.7
-
24
-
-
0141889125
-
Blockade of B7-H1 suppresses the development of chronic intestinal inflammation
-
Kanai T, Totsuka T, Uraushihara K, et al: Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. J Immunol 171: 4156-4163, 2003.
-
(2003)
J Immunol
, vol.171
, pp. 4156-4163
-
-
Kanai, T.1
Totsuka, T.2
Uraushihara, K.3
-
25
-
-
34248523197
-
+ T-cell proliferation via apoptosis
-
+ T-cell proliferation via apoptosis. Cell Biol Int 31: 784-789, 2007.
-
(2007)
Cell Biol Int
, vol.31
, pp. 784-789
-
-
Shu, L.1
Yin, W.2
Zhang, J.3
Tang, B.4
Kang, Y.X.5
Ding, F.6
Hua, Z.C.7
-
26
-
-
15744402274
-
Requirement for ERK activation in sinomenine-induced apoptosis of macrophages
-
He X, Wang J, Guo Z, Liu Q, Chen T, Wang X and Cao X: Requirement for ERK activation in sinomenine-induced apoptosis of macrophages. Immunol Lett 98: 91-96, 2005.
-
(2005)
Immunol Lett
, vol.98
, pp. 91-96
-
-
He, X.1
Wang, J.2
Guo, Z.3
Liu, Q.4
Chen, T.5
Wang, X.6
Cao, X.7
-
27
-
-
14844320581
-
Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats
-
Wang Y, Fang Y, Huang W, Zhou X, Wang M, Zhong B and Peng D: Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats. J Ethnopharmacol 98: 37-43, 2005.
-
(2005)
J Ethnopharmacol
, vol.98
, pp. 37-43
-
-
Wang, Y.1
Fang, Y.2
Huang, W.3
Zhou, X.4
Wang, M.5
Zhong, B.6
Peng, D.7
-
28
-
-
20444444826
-
Effect of Sinomenine on IL-8, IL-6, IL-2 produced by peripheral blood mononuclear cells
-
Tu S, Hu Y and Lu F: Effect of Sinomenine on IL-8, IL-6, IL-2 produced by peripheral blood mononuclear cells. J Tongji Med Univ 19: 257-259, 1999.
-
(1999)
J Tongji Med Univ
, vol.19
, pp. 257-259
-
-
Tu, S.1
Hu, Y.2
Lu, F.3
-
29
-
-
2442551466
-
Effect of sinomenine on apoptosis of synoviocytes in CIA rats
-
In Chinese
-
Huang QC, Chen JF, Chen GX, et al: Effect of sinomenine on apoptosis of synoviocytes in CIA rats. Zhongguo Lin Chuang Kang Fu 6: 2541-2548, 2002 (In Chinese).
-
(2002)
Zhongguo Lin Chuang Kang Fu
, vol.6
, pp. 2541-2548
-
-
Huang, Q.C.1
Chen, J.F.2
Chen, G.X.3
-
30
-
-
33947395563
-
Sinomenine inhibits maturation of monocyte-derived dendritic cells through blocking activation of NF-kappa B
-
Zhao Y, Li J, Yu K, Liu Y and Chen X: Sinomenine inhibits maturation of monocyte-derived dendritic cells through blocking activation of NF-kappa B. Int Immunopharmacol 7: 637-645, 2007.
-
(2007)
Int Immunopharmacol
, vol.7
, pp. 637-645
-
-
Zhao, Y.1
Li, J.2
Yu, K.3
Liu, Y.4
Chen, X.5
|