Complement-regulator factor H and related proteins in Otitis media with effusion

Clinical Immunology

Volumn 100, Issue 1, 2001, Pages 118-126

  Närkiö Mäkelä, Mervi ^a,b   Hellwage, Jens ^a,c   Tahkokallio, Olli ^d   Meri, Seppo ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c HANS KNÖLL INSTITUTE   (Germany)

^d JORVI HOSPITAL   (Finland)

Author keywords

Complement activation; Factor H; FHL 1; FHR 1; FHR 2; FHR 3; FHR 4; FHR 5; OME; Otitis media with effusion

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT FACTOR H;

ANIMAL CELL; ARTICLE; BINDING SITE; CHRONIC INFLAMMATION; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT SYSTEM; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMOLYSIS; MIDDLE EAR EFFUSION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; SECRETORY OTITIS MEDIA;

EID: 0034974922     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.2001.5043     Document Type: Article

References (27)

1. Otitis media with effusion in preschool children
2. Panel reports, definition and classification
3. Classification of otitis media
4. Chronic otitis media with effusion in infancy
5. The C3-activator system: An alternate pathway of complement activation
6. C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
7. The alternative pathway of complement
8. Complement activation and expression of membrane regulators in the middle ear mucosa in otitis media with effusion
9. Cytolytic complement activity in otitis media with effusion
10. Complement C3 cleavage and cytokines interleukin-1β and tumor necrosis-factor -α in otitis media with effusion
11. Structural analysis of human complement protein H: Homology with C4b binding protein, β2-glycoprotein I, and the Ba fragment of B
12. Factor H and disease: A complement regulator affects vital body functions
13. Fluid phase RCA proteins, factor H
14. FHL-1: A human complement and immune regulator with cell-adhesive function
15. Mapping of the domains required for decay acceleration activity of the human factor H-like protein 1 and factor H
16. Plasma lipopolysaccharide-binding proteins found associated with a particle containing apolipoprotein A-I, phospholipid, and factor H-related proteins
17. Functional properties of complement factor H-related proteins FHR-3 and FHR-4: Binding to the C3d region of C3b and differential regulation by heparin
18. Complement in chronic secretory otitis media
19. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4
20. Biochemical and functional characterization of the factor-H-related protein 4 (FHR-4)
21. The baculovirus expression vector pBSV-8His directs secretion of histidine-tagged proteins
22. The C-terminus of factor H: Monoclonal antibodies inhibit heparin binding and identify epitopes common to factor H and factor H-related proteins
23. Human factor H-related protein 5 (FHR-5): A new complement-associated protein
24. Identification of second heparin-binding domain in human complement factor H
25. The alternative pathway of complement - A system for host resistance to microbial infection
26. Each of the three binding sites on complement factor H interacts with a distinct site on C3b
27. PCR assay for detecting Streptococcus pneumoniae in middle ear of children with otitis media with effusion