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Volumn 23, Issue 3, 2013, Pages 160-168

The role of gut microbiota in human obesity: Recent findings and future perspectives

Author keywords

Bacterial strains; Gut microbiota; Obesity; Overweight

Indexed keywords

ADIPOSE TISSUE; ANIMAL; GASTROINTESTINAL TRACT; HUMAN; LIPID DIET; METABOLISM; METAGENOME; MICROBIOLOGY; OBESITY; REVIEW; WEIGHT GAIN;

EID: 84875233230     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2012.09.002     Document Type: Review
Times cited : (98)

References (48)
  • 1
    • 84875264647 scopus 로고    scopus 로고
    • World health Organization - Obesity and overweight - Fact sheet N°311-updated March 2011.
    • World health Organization - Obesity and overweight - Fact sheet N°311-updated March 2011. http://www.who.int/mediacentre/factsheets/fs311/en/index.html.
  • 5
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley R.E., Turnbaugh P.J., Klein S., Gordon J.I. Microbial ecology: human gut microbes associated with obesity. Nature 2006, 444:1009-1010.
    • (2006) Nature , vol.444 , pp. 1009-1010
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 6
    • 83755222630 scopus 로고    scopus 로고
    • Microbial eukaryotes in the human microbiome: ecology, evolution, and future directions
    • Parfrey L.W., Walters W.A., Knight R. Microbial eukaryotes in the human microbiome: ecology, evolution, and future directions. Front Microbiol 2011, 2:1-6.
    • (2011) Front Microbiol , vol.2 , pp. 1-6
    • Parfrey, L.W.1    Walters, W.A.2    Knight, R.3
  • 7
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • Frank D.N., St Amand A.L., Feldman R.A., Boedeker E.C., Harpaz N., Pace N.R. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A 2007, 104:13780-13785.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13780-13785
    • Frank, D.N.1    St Amand, A.L.2    Feldman, R.A.3    Boedeker, E.C.4    Harpaz, N.5    Pace, N.R.6
  • 8
    • 44649118583 scopus 로고    scopus 로고
    • Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases
    • Peterson D.A., Frank D.N., Pace N.R., Gordon J.I. Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe 2008, 3:417-427.
    • (2008) Cell Host Microbe , vol.3 , pp. 417-427
    • Peterson, D.A.1    Frank, D.N.2    Pace, N.R.3    Gordon, J.I.4
  • 12
    • 77954254522 scopus 로고    scopus 로고
    • Improvement of the representation of bifidobacteria in fecal microbiota metagenomic libraries by application of the cpn60 universal primer cocktail
    • Hill J.E., Ursla Fernando W.M., Zello G.A., Tyler R.T., Dahl W.J., Van Kessel A.J. Improvement of the representation of bifidobacteria in fecal microbiota metagenomic libraries by application of the cpn60 universal primer cocktail. Appl Environ Microbiol 2010, 76(13):4550-4552.
    • (2010) Appl Environ Microbiol , vol.76 , Issue.13 , pp. 4550-4552
    • Hill, J.E.1    Ursla Fernando, W.M.2    Zello, G.A.3    Tyler, R.T.4    Dahl, W.J.5    Van Kessel, A.J.6
  • 14
    • 84859014125 scopus 로고    scopus 로고
    • Improved detection of bifidobacteria with optimised 16S rRNA-gene based pyrosequencing
    • Sim K., Cox M.J., Wopereis H., Martin R., Knol J., Li M.S., et al. Improved detection of bifidobacteria with optimised 16S rRNA-gene based pyrosequencing. PLoS One 2012, 7(3):e32543. 10.1371/journal.pone.0032543.
    • (2012) PLoS One , vol.7 , Issue.3
    • Sim, K.1    Cox, M.J.2    Wopereis, H.3    Martin, R.4    Knol, J.5    Li, M.S.6
  • 15
    • 80054111810 scopus 로고    scopus 로고
    • Fermentation in the human large intestine its physiologic consequences and the potential contribution of prebiotics
    • Macfarlane G.T., Macfarlane S. Fermentation in the human large intestine its physiologic consequences and the potential contribution of prebiotics. J Clin Gastroenterol 2011, 45:S120-S127.
    • (2011) J Clin Gastroenterol , vol.45
    • Macfarlane, G.T.1    Macfarlane, S.2
  • 16
    • 33847233644 scopus 로고    scopus 로고
    • Reduced dietary intake of carbohydrate, by obese subjects, results in decreased concentrations of butyrate and butyrate-producing bacteria in feces
    • Duncan S.H., Belenguer A., Holtrop G., Johnstone A.M., Flint H.J., Lobley G.E. Reduced dietary intake of carbohydrate, by obese subjects, results in decreased concentrations of butyrate and butyrate-producing bacteria in feces. Appl Environ Microbiol 2007, 73:1073-1078.
    • (2007) Appl Environ Microbiol , vol.73 , pp. 1073-1078
    • Duncan, S.H.1    Belenguer, A.2    Holtrop, G.3    Johnstone, A.M.4    Flint, H.J.5    Lobley, G.E.6
  • 17
    • 12344249654 scopus 로고    scopus 로고
    • Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial
    • Furrie E., Macfarlane S., Kennedy A., Cummings J.H., Walsh S.V., O'Neill D.A., et al. Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial. Gut 2005, 54:242-249.
    • (2005) Gut , vol.54 , pp. 242-249
    • Furrie, E.1    Macfarlane, S.2    Kennedy, A.3    Cummings, J.H.4    Walsh, S.V.5    O'Neill, D.A.6
  • 18
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh P.J., Ley R.E., Mahowald M.A., Magrini V., Mardis E.R., Gordon J.I. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444:1027-1031.
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 19
    • 0021349077 scopus 로고
    • The contribution of the large intestine to energy supplies in man
    • McNeil N.I. The contribution of the large intestine to energy supplies in man. Am J Clin Nutr 1984, 39:338-342.
    • (1984) Am J Clin Nutr , vol.39 , pp. 338-342
    • McNeil, N.I.1
  • 23
    • 84916629303 scopus 로고    scopus 로고
    • World Cancer Research Fund and American Institute for Cancer Research Food
    • 336-338, AIRC, Washington DC
    • World Cancer Research Fund and American Institute for Cancer Research Food Nutrition, physical activity and the prevention of cancer: a global perspective 2007, 336-338, AIRC, Washington DC. http://www.wcrf.org/research/policy_report/recommendations.php.
    • (2007) Nutrition, physical activity and the prevention of cancer: a global perspective
  • 24
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 25
    • 34347399563 scopus 로고    scopus 로고
    • Metabolic endotoxemia initiates obesity and insulin resistance
    • Cani P., Amar J., Iglesias M.A., Poggi M., Knauf C., Bastelica D., et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007, 56:1761-1772.
    • (2007) Diabetes , vol.56 , pp. 1761-1772
    • Cani, P.1    Amar, J.2    Iglesias, M.A.3    Poggi, M.4    Knauf, C.5    Bastelica, D.6
  • 30
    • 70349631208 scopus 로고    scopus 로고
    • Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and methanogens in anorexic patients
    • Armougom F., Henry M., Vialettes B., Raccah D., Raoult D. Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and methanogens in anorexic patients. PLoS One 2009, 4:e7125.
    • (2009) PLoS One , vol.4
    • Armougom, F.1    Henry, M.2    Vialettes, B.3    Raccah, D.4    Raoult, D.5
  • 32
    • 78650037263 scopus 로고    scopus 로고
    • Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss links with metabolic and low-grade inflammation markers
    • Furet J.P., Kong L.C., Tap J., Poitou C., Basdevant A., Bouillot J.L., et al. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss links with metabolic and low-grade inflammation markers. Diabetes 2010, 59:3049-3057.
    • (2010) Diabetes , vol.59 , pp. 3049-3057
    • Furet, J.P.1    Kong, L.C.2    Tap, J.3    Poitou, C.4    Basdevant, A.5    Bouillot, J.L.6
  • 33
    • 53849104768 scopus 로고    scopus 로고
    • Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women
    • Collado M.C., Isolauri E., Laitinen K., Salminen S. Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women. Am J Clin Nutr 2008, 88:894-899.
    • (2008) Am J Clin Nutr , vol.88 , pp. 894-899
    • Collado, M.C.1    Isolauri, E.2    Laitinen, K.3    Salminen, S.4
  • 34
    • 79955938052 scopus 로고    scopus 로고
    • Gut bacteria alteration in obese people and its relationship with gene polymorphism
    • Zuo H.J., Xie Z.M., Zhang W.W., Li Y.R., Wang W., Ding X.B., et al. Gut bacteria alteration in obese people and its relationship with gene polymorphism. World J Gastroenterol 2011, 17:1076-1081.
    • (2011) World J Gastroenterol , vol.17 , pp. 1076-1081
    • Zuo, H.J.1    Xie, Z.M.2    Zhang, W.W.3    Li, Y.R.4    Wang, W.5    Ding, X.B.6
  • 35
    • 84862230115 scopus 로고    scopus 로고
    • Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii
    • Million M., Maraninchi M., Henry M., Armougom F., Raoult D. Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii. Int J Obes (Lond) 2011, 10.1038/ijo.2011.153.
    • (2011) Int J Obes (Lond)
    • Million, M.1    Maraninchi, M.2    Henry, M.3    Armougom, F.4    Raoult, D.5
  • 37
    • 72449190581 scopus 로고    scopus 로고
    • Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers
    • Mai V., McCrary Q.M., Sinha R., Glei M. Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers. Nutr J 2009, 8:49.
    • (2009) Nutr J , vol.8 , pp. 49
    • Mai, V.1    McCrary, Q.M.2    Sinha, R.3    Glei, M.4
  • 38
    • 79959467647 scopus 로고    scopus 로고
    • Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans
    • Jumpertz R., Le D.S., Turnbaugh P.J., Trinidad C., Bogardus C., Gordon J.I., et al. Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. Am J Clin Nutr 2011, 94:58-65.
    • (2011) Am J Clin Nutr , vol.94 , pp. 58-65
    • Jumpertz, R.1    Le, D.S.2    Turnbaugh, P.J.3    Trinidad, C.4    Bogardus, C.5    Gordon, J.I.6
  • 39
    • 78751580602 scopus 로고    scopus 로고
    • Dominant and diet-responsive groups of bacteria within the human colonic microbiota
    • Walker A.W., Ince J., Duncan S.H., Webster L.M., Holtrop G., Ze X., et al. Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME J 2011, 5:220-230.
    • (2011) ISME J , vol.5 , pp. 220-230
    • Walker, A.W.1    Ince, J.2    Duncan, S.H.3    Webster, L.M.4    Holtrop, G.5    Ze, X.6
  • 40
    • 67650445962 scopus 로고    scopus 로고
    • Shifts in clostridia, bacteroides and immunoglobulincoating fecal bacteria associated with weight loss in obese adolescents
    • Nadal I., Santacruz A., Marcos A., Warnberg J., Garagorri M., Moreno L.A., et al. Shifts in clostridia, bacteroides and immunoglobulincoating fecal bacteria associated with weight loss in obese adolescents. Int J Obes 2009, 33:758-767.
    • (2009) Int J Obes , vol.33 , pp. 758-767
    • Nadal, I.1    Santacruz, A.2    Marcos, A.3    Warnberg, J.4    Garagorri, M.5    Moreno, L.A.6
  • 41
    • 79955383693 scopus 로고    scopus 로고
    • High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health
    • Russell W.R., Gratz S.W., Duncan S.H., Holtrop G., Ince J., Scobbie L., et al. High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health. Am J Clin Nutr 2011, 93:1062-1072.
    • (2011) Am J Clin Nutr , vol.93 , pp. 1062-1072
    • Russell, W.R.1    Gratz, S.W.2    Duncan, S.H.3    Holtrop, G.4    Ince, J.5    Scobbie, L.6
  • 42
    • 70349502267 scopus 로고    scopus 로고
    • Interplay between weight loss and gut microbiota composition in overweight adolescents
    • Santacruz A., Marcos A., Wärnberg J., Martí A., Martin-Matillas M., Campoy C., et al. Interplay between weight loss and gut microbiota composition in overweight adolescents. Obesity 2009, 17:1906-1915.
    • (2009) Obesity , vol.17 , pp. 1906-1915
    • Santacruz, A.1    Marcos, A.2    Wärnberg, J.3    Martí, A.4    Martin-Matillas, M.5    Campoy, C.6
  • 43
    • 79955016294 scopus 로고    scopus 로고
    • Diabetes resolution and hyperinsulinaemia after metabolic Roux-en-Y gastric bypass
    • Ashrafian H., Athanasiou T., Li J.V., Bueter M., Ahmed K., Nagpal K., et al. Diabetes resolution and hyperinsulinaemia after metabolic Roux-en-Y gastric bypass. Obes Rev 2011, 12:e257-e272.
    • (2011) Obes Rev , vol.12
    • Ashrafian, H.1    Athanasiou, T.2    Li, J.V.3    Bueter, M.4    Ahmed, K.5    Nagpal, K.6
  • 44
    • 74249119678 scopus 로고    scopus 로고
    • Obesity and the human microbiome
    • Ley R.E. Obesity and the human microbiome. Curr Op Gastroenterol 2010, 26:5-11.
    • (2010) Curr Op Gastroenterol , vol.26 , pp. 5-11
    • Ley, R.E.1
  • 46
    • 77957075815 scopus 로고    scopus 로고
    • Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
    • De Filippo C., Cavalieria D., Di Paola M., Ramazzotti M., Poullet J.B., Massart S., et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A 2010, 107:14691-14696.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14691-14696
    • De Filippo, C.1    Cavalieria, D.2    Di Paola, M.3    Ramazzotti, M.4    Poullet, J.B.5    Massart, S.6
  • 48
    • 79959212036 scopus 로고    scopus 로고
    • Vagal afferent neurons in high fat diet-induced obesity; intestinal microflora, gut inflammation and cholecystokinin
    • De Lartigue G., Barbier de La Serre C., Raybould H.E. Vagal afferent neurons in high fat diet-induced obesity; intestinal microflora, gut inflammation and cholecystokinin. Physiol Behav 2011, 105:100-105.
    • (2011) Physiol Behav , vol.105 , pp. 100-105
    • De Lartigue, G.1    Barbier de La Serre, C.2    Raybould, H.E.3


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