Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties

EMBO Journal

Volumn 32, Issue 5, 2013, Pages 756-769

  Cancellotti, Enrico ^a   Mahal, Sukhvir P ^b   Somerville, Robert ^a   Diack, Abigail ^a   Brown, Deborah ^a   Piccardo, Pedro ^a,c   Weissmann, Charles ^b   Manson, Jean C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b Department of Infectology Scripps Florida ^*  (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

glycosylation; phenotypic change; prion; transmissible spongiform encephalopathy

Indexed keywords

PRION PROTEIN;

AMINO ACID SEQUENCE; BRAIN STEM; GLYCOSYLATION; HUMAN; IN VIVO STUDY; MESENCEPHALON; PHENOTYPE; PRION DISEASE; PRIORITY JOURNAL; REVIEW; THALAMUS; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; BRAIN; CELLS, CULTURED; FEMALE; GLYCOSYLATION; IMMUNOENZYME TECHNIQUES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUROBLASTOMA; POLYSACCHARIDES; PRION DISEASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PRPSC PROTEINS; VIRUS REPLICATION;

MUS; MUS MUSCULUS;

EID: 84875229692     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.6     Document Type: Review

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