Gender differences in the bronchoalveolar lavage cell proteome of patients with chronic obstructive pulmonary disease

Journal of Allergy and Clinical Immunology

Volumn 131, Issue 3, 2013, Pages

  Kohler, Maxie ^a   Sandberg, Annsofi ^a   Kjellqvist, Sanela ^b   Thomas, Andreas ^c   Karimi, Reza ^a   Nyrén, Sven ^a   Eklund, Anders ^a   Thevis, Mario ^c   Sköld, C Magnus ^a   Wheelock, Åsa M ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

Author keywords

alveolar macrophage; bronchoalveolar lavage; Chronic obstructive pulmonary disease; difference gel electrophoresis; gender; multivariate modeling; proteomics

Indexed keywords

CELL PROTEIN;

ADULT; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS MACROPHAGE; LYSOSOME; MACROAUTOPHAGY; MACROPHAGE; MALE; MASS SPECTROMETRY; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PRIORITY JOURNAL; PROTEOMICS; SEX DIFFERENCE; SMOKING; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS; UPREGULATION; WESTERN BLOTTING;

EID: 84875225719     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.09.024     Document Type: Article

References (62)

1. C.D. Mathers, T. Boerma, and D. Ma Fat Global and regional causes of death Br Med Bull 92 2009 7 32
2. A.D. Lopez, and C.C. Murray The global burden of disease, 1990-2020 Nat Med 4 1998 1241 1243
3. J. Ohar, L. Fromer, and J.F. Donohue Reconsidering sex-based stereotypes of COPD Prim Care Respir J 20 2011 370 378
4. B. Lundback, A. Lindberg, M. Lindstrom, E. Ronmark, A.C. Jonsson, and E. Jonsson Not 15 but 50% of smokers develop COPD? - report from the Obstructive Lung Disease in Northern Sweden studies Respir Med 97 2003 115 122
5. R.A. Stockley, D. Mannino, and P.J. Barnes Burden and pathogenesis of chronic obstructive pulmonary disease Proc Am Thorac Soc 6 2009 524 526
6. D.M. Mannino, D.M. Homa, L.J. Akinbami, E.S. Ford, and S.C. Redd Chronic obstructive pulmonary disease surveillance - United States, 1971-2000 MMWR Surveill Summ 51 2002 1 16
7. N.K. Jain, M.S. Thakkar, N. Jain, K.A. Rohan, and M. Sharma Chronic obstructive pulmonary disease: does gender really matter? Lung India 28 2011 258 262
8. P.G. Camp, H.O. Coxson, R.D. Levy, S.G. Pillai, W. Anderson, and J. Vestbo Sex differences in emphysema and airway disease in smokers Chest 136 2009 1480 1488
9. M.T. Dransfield, J.J. Davis, L.B. Gerald, and W.C. Bailey Racial and gender differences in susceptibility to tobacco smoke among patients with chronic obstructive pulmonary disease Respir Med 100 2006 1110 1116
10. T.B. Grydeland, A. Dirksen, H.O. Coxson, S.G. Pillai, S. Sharma, and G.E. Eide Quantitative computed tomography: emphysema and airway wall thickness by sex, age and smoking Eur Respir J 34 2009 858 865
11. E.A. Townsend, V.M. Miller, and Y.S. Prakash Sex Differences and Sex Steroids in Lung Health and Disease Endocr Rev 33 2012 1 47
12. W.Q. Gan, S.F. Man, D.S. Postma, P. Camp, and D.D. Sin Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis Respir Res 7 2006 52
13. I.C. Sorheim, A. Johannessen, A. Gulsvik, P.S. Bakke, E.K. Silverman, and D.L. DeMeo Gender differences in COPD: are women more susceptible to smoking effects than men? Thorax 65 2010 480 485
14. S. Ohlmeier, W. Mazur, A. Linja-Aho, N. Louhelainen, M. Ronty, and T. Toljamo Sputum proteomics identifies elevated PIGR levels in smokers and mild-to-moderate COPD J Proteome Res 11 2012 599 608
15. B. Casado, M. Luisetti, and P. Iadarola Advances in proteomic techniques for biomarker discovery in COPD Expert Rev Clin Immunol 7 2011 111 123
16. H. Chen, D. Wang, C. Bai, and X. Wang Proteomics-based biomarkers in chronic obstructive pulmonary disease J Proteome Res 9 2010 2798 2808
17. N. Waldburg, T. Kahne, A. Reisenauer, C. Rocken, T. Welte, and F. Buhling Clinical proteomics in lung diseases Pathol Res Pract 200 2004 147 154
18. N.M. Verrills, J.A. Irwin, X.Y. He, L.G. Wood, H. Powell, and J.L. Simpson Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease Am J Respir Crit Care Med 183 2011 1633 1643
19. A.K. Tewari, A. Popova-Butler, M.A. El-Mahdy, and J.L. Zweier Identification of differentially expressed proteins in blood plasma of control and cigarette smoke-exposed mice by 2-D DIGE/MS Proteomics 11 2011 2051 2062
20. B.L. Nicholas, C.D. O'Connor, and R. Djukanovic From proteomics to prescription-the search for COPD biomarkers COPD 6 2009 298 303
21. R. Hu, Q. Ouyang, A. Dai, S. Tan, Z. Xiao, and C. Tang Heat shock protein 27 and cyclophilin A associate with the pathogenesis of COPD Respirology 16 2011 983 993
22. B. Magi, E. Bargagli, L. Bini, and P. Rottoli Proteome analysis of bronchoalveolar lavage in lung diseases Proteomics 6 2006 6354 6369
23. T.P. York, E.J. van den Oord, T.B. Langston, J.S. Edmiston, W. McKinney, and B.T. Webb High-resolution mass spectrometry proteomics for the identification of candidate plasma protein biomarkers for chronic obstructive pulmonary disease Biomarkers 15 2010 367 377
24. A. Plymoth, C.G. Lofdahl, A. Ekberg-Jansson, M. Dahlback, P. Broberg, and M. Foster Protein expression patterns associated with progression of chronic obstructive pulmonary disease in bronchoalveolar lavage of smokers Clin Chem 53 2007 636 644
25. E.J. Lee, K.H. In, J.H. Kim, S.Y. Lee, C. Shin, and J.J. Shim Proteomic analysis in lung tissue of smokers and COPD patients Chest 135 2009 344 352
26. J.P. de Torres, C. Casanova, V. Pinto-Plata, N. Varo, P. Restituto, and E. Cordoba-Lanus Gender differences in plasma biomarker levels in a cohort of COPD patients: a pilot study PLoS One 6 2011 e16021
27. S. Larsson, A. Nordenson, P. Glader, S. Yoshihara, A. Linden, and F. Slinde A gender difference in circulating neutrophils in malnourished patients with COPD Int J Chron Obstruct Pulmon Dis 6 2011 83 88
28. P.J. Barnes Alveolar macrophages as orchestrators of COPD COPD 1 2004 59 70
29. J.B. Morjaria, M. Malerba, and R. Polosa Biologic and pharmacologic therapies in clinical development for the inflammatory response in COPD Drug Discov Today 15 2010 396 405
30. R. Shaykhiev, A. Krause, J. Salit, Y. Strulovici-Barel, B.G. Harvey, and T.P. O'Connor Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease J Immunol 183 2009 2867 2883
31. J.M. Lofdahl, J. Wahlstrom, and C.M. Skold Different inflammatory cell pattern and macrophage phenotype in chronic obstructive pulmonary disease patients, smokers and non-smokers Clin Exp Immunol 145 2006 428 437
32. J. Stocks, and P.H. Quanjer Reference values for residual volume, functional residual capacity and total lung capacity. ATS Workshop on Lung Volume Measurements. Official Statement of The European Respiratory Society Eur Respir J 8 1995 492 506
33. A. Eklund, and E. Blaschke Relationship between changed alveolar-capillary permeability and angiotensin converting enzyme-activity in serum in sarcoidosis Thorax 41 1986 629 634
34. J.M. Lofdahl, K. Cederlund, L. Nathell, A. Eklund, and C.M. Skold Bronchoalveolar lavage in COPD: fluid recovery correlates with the degree of emphysema Eur Respir J 25 2005 275 281
35. J. Storey A direct approach to false discovery rates J R Stat Soc B 64 2002 479 498
36. J.E. Jackson A user's guide to principal components 1991 John Wiley New York
37. J. Trygg, and S. Wold Orthogonal projections to latent structures (O-PLS) J Chemometrics 16 2002 119 128
38. J.X. Yan, R. Wait, T. Berkelman, R.A. Harry, J.A. Westbrook, and C.H. Wheeler A modified silver staining protocol for visualization of proteins compatible with matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry Electrophoresis 21 2000 3666 3672
39. J.K. Eng, A.L. Mccormack, and J.R. Yates An approach to correlate tandem mass-spectral data of peptides with amino-acid-sequences in a protein database J Am Soc Mass Spectrom 5 1994 976 989
40. G. Dennis Jr., B.T. Sherman, D.A. Hosack, J. Yang, W. Gao, and H.C. Lane DAVID: database for annotation, visualization, and integrated discovery Genome Biol 4 2003 P3
41. W. Huang da, B.T. Sherman, and R.A. Lempicki Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat Protoc 4 2009 44 57
42. W. Huang da, B.T. Sherman, and R.A. Lempicki Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists Nucleic Acids Res 37 2009 1 13
43. H. Ogata, S. Goto, K. Sato, W. Fujibuchi, H. Bono, and M. Kanehisa KEGG: Kyoto encyclopedia of genes and genomes Nucleic Acids Res 27 1999 29 34
44. M. Kanehisa, S. Goto, Y. Sato, M. Furumichi, and M. Tanabe KEGG for integration and interpretation of large-scale molecular data sets Nucleic Acids Res 40 Database issue 2012 D109 D114
45. S.I. Rennard, M. Ghafouri, A.B. Thompson, J. Linder, W. Vaughan, and K. Jones Fractional processing of sequential bronchoalveolar lavage to separate bronchial and alveolar samples Am Rev Respir Dis 141 1990 208 217
46. J. Schildge, C. Nagel, and C. Grun Bronchoalveolar lavage in interstitial lung diseases: does the recovery rate affect the results? Respiration 74 2007 553 557
47. E. Silva, M. O'Gorman, S. Becker, G. Auer, A. Eklund, and J. Grunewald In the eye of the beholder: does the master see the same spots as the novice? J Proteome Res 9 2010 1522 1532
48. J. Trygg, and S. Wold Orthogonal Projections to Latent Structures (OPLS) J Chemometrics 16 2002 119 128
49. E. Jain, A. Bairoch, S. Duvaud, I. Phan, N. Redaschi, and B.E. Suzek Infrastructure for the life sciences: design and implementation of the UniProt website BMC Bioinformatics 10 2009 136
50. Ongoing and future developments at the Universal Protein Resource Nucleic Acids Res 39 Database issue 2011 D214 D219
51. J.A. Haspel, and A.M. Choi Autophagy: a core cellular process with emerging links to pulmonary disease Am J Respir Crit Care Med 184 2011 1237 1246
52. M.M. Monick, L.S. Powers, K. Walters, N. Lovan, M. Zhang, and A. Gerke Identification of an autophagy defect in smokers' alveolar macrophages J Immunol 185 2010 5425 5435
53. F.J. Martinez, J.L. Curtis, F. Sciurba, J. Mumford, N.D. Giardino, and G. Weinmann Sex differences in severe pulmonary emphysema Am J Respir Crit Care Med 176 2007 243 252
54. M. Decramer, F. De Benedetto, A. Del Ponte, and S. Marinari Systemic effects of COPD Respir Med 99 suppl B 2005 S3 S10
55. H.J. Green, E. Bombardier, M. Burnett, S. Iqbal, C.L. D'Arsigny, and D.E. O'Donnell Organization of metabolic pathways in vastus lateralis of patients with chronic obstructive pulmonary disease Am J Physiol Regul Integr Comp Physiol 295 2008 R935 R941
56. T.L. Verhage, Y. Heijdra, J. Molema, J. Vercoulen, and R. Dekhuijzen Associations of muscle depletion with health status. Another gender difference in COPD? Clin Nutr 30 2011 332 338
57. M.A. Vermeeren, E.C. Creutzberg, A.M. Schols, D.S. Postma, W.R. Pieters, and A.C. Roldaan Prevalence of nutritional depletion in a large out-patient population of patients with COPD Respir Med 100 2006 1349 1355
58. A. Eklund, and E. Blaschke Relationship between changed alveolar-capillary permeability and angiotensin converting enzyme-activity in serum in sarcoidosis Thorax 41 1986 629 634
59. J.M. Lofdahl, K. Cederlund, L. Nathell, A. Eklund, and C.M. Skold Bronchoalveolar lavage in COPD: fluid recovery correlates with the degree of emphysema Eur Respir J 25 2005 275 281
60. J.X. Yan, R. Wait, T. Berkelman, R.A. Harry, J.A. Westbrook, and C.H. Wheeler A modified silver staining protocol for visualization of proteins compatible with matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry Electrophoresis 21 2000 3666 3672
61. F. Gharahdaghi, C.R. Weinberg, D.A. Meagher, B.S. Imai, and S.M. Mische Mass spectrometric identification of proteins from silver-stained polyacrylamide gel: a method for the removal of silver ions to enhance sensitivity Electrophoresis 20 1999 601 605
62. J.K. Eng, A.L. Mccormack, and J.R. Yates An approach to correlate tandem mass-spectral data of peptides with amino-acid-sequences in a protein database J Am Soc Mass Spectrom 5 1994 976 989