Analysis of the lung transcriptome in Mycobacterium tuberculosis-infected mice reveals major differences in immune response pathways between TB-susceptible and resistant hosts

Tuberculosis

Volumn 93, Issue 2, 2013, Pages 263-269

  Shepelkova, Galina ^c   Pommerenke, Claudia ^a   Alberts, Rudi ^a   Geffers, Robert ^a   Evstifeev, Vladimir ^c   Apt, Alexander ^c   Schughart, Klaus ^a,b   Wilk, Esther ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^c CENTRAL TUBERCULOSIS RESEARCH INSTITUTE   (Russian Federation)

Author keywords

Cysteine protease inhibitors; Gene expression study; Host genetic factors; Mouse infection model

Indexed keywords

CYSTATIN; GAMMA INTERFERON; RANTES; TRANSCRIPTOME; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GRANULOCYTE; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNOREGULATION; INFECTION SENSITIVITY; LEUKOCYTE ACTIVATION; LUNG TUBERCULOSIS; LYMPHOCYTE PROLIFERATION; MAST CELL; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; UPREGULATION;

ANIMALS; ANTIGEN PRESENTATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GRANULOCYTES; LUNG; MALE; MICE; MICE, INBRED A; MICE, INBRED STRAINS; NEUTROPHIL INFILTRATION; SALIVARY CYSTATINS; SPECIES SPECIFICITY; TRANSCRIPTOME; TUBERCULOSIS, PULMONARY; UP-REGULATION;

EID: 84875221843     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2012.11.007     Document Type: Article

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