An ex vivo study of T lymphocytes recovered from the lungs of I/St mice infected with and susceptible to Mycobacterium tuberculosis

Infection and Immunity

Volumn 66, Issue 10, 1998, Pages 4981-4988

  Lyadova, Irina ^a   Yeremeev, Vladimir ^a   Majorov, Konstantin ^a   Nikonenko, Boris ^a   Khaidukov, Sergei ^b   Kondratieva, Tatiana ^a   Kobets, Natalia ^a   Apt, Alexander ^a  

^a CENTRAL TUBERCULOSIS RESEARCH INSTITUTE   (Russian Federation)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BACTERIAL GROWTH; COLONY FORMING UNIT; CONTROLLED STUDY; GROWTH INHIBITION; LUNG ALVEOLUS CELL; LYMPHOCYTE PROLIFERATION; MYCOBACTERIOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TUBERCULOSIS;

EID: 0031691929     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.10.4981-4988.1998     Document Type: Article

References (42)

1. Andersen, P. 1994. Effective vaccination of mice against Mycobacterium tuberculosis infection with a soluble mixture of secreted myeobacterial proteins. Infect. Immun, 62:2536-2544.
2. Apt, A. S., V. G. Avdienko, B. V. Nikonenko, A. M. Muroz, and E. Skamene. 1993. Distinct H-2 complex control of mortality, and immune responses to tuberculosis infection in virgin and BCG-vaccinated mice. Clin. Exp. Immunol. 94:322-329.
3. Apt, A. S., I. B. Kramnik, and A. M. Moroz. 1991. Regulation of T cell proliferative responses by cells from solid lung tissue of M. tuberculosis-infected mice. Immunology 73:73-179.
4. Apt, A. S., B. V. Nikunenko, A. M. Moroz, and M. M. Averbakh. 1982. Genetic analysis of factors determining susceptibility to tuberculosis. Bull. Exp. Biol. Med. 12:83-85. (In Russian.)
5. Avdienko, V. G., S. Y. Kondrashov. I. V. Shabunin, and V. I. Litvinov. Two distinct antigens from Mycobacterium tuberculosis and their use for detection of specific antibodies in sera of TB patients by ELISA. Probl. Tuberc., in press.
6. Boesen, H., B. N. Jensen, T. Wilcke, and P. Andersen. 1995. Human T-cell responses to secreted antigen fractions of Mycobacterculosis. Infect. Immun. 63:1491-1497.
7. Budd, R. C., J. Cerottini, C. Horvath, C. Bron, T. Pedrazzini, and R. C. MacDonald. 1987. Distinction of origin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation. J. Immunol. 138:3120-3129.
8. Buschman, E., A. S. Apt, B. V. Niknnenko, A. M. Moroz, M. M. Averbakh. and E. Skamene. 1988. Genetics aspects of innate resistance and acquired immunity to mycobacteria in inbred mice. Springer Semin. Immunopathol. 10:319-333.
9. + helper T lymphocytes identified by expression of Pgp-1. J. Exp. Med. 169:1461-1466.
10. Dannenberg, A. M., Jr, 1983. Pathogenesis of tuberculosis: native and acquired resistance in animals and humans, p. 344-354. In Immunology of tuberculosis and leprosy: a symposium. US-Japan Cooperative Medical Sciences Program. Bethesda. Md.
11. Dianzani, U., M. Luqman, J. Rojo, J. Yagi, J. L. Baron, A. Woods, C. Janeway, and K. Bottomly. 1990. Molecular associations on the T cell surface correlate with immunological memory. Eur. J. Immunol. 20:2249-2257.
12. Dunn, P. L., and R. J. North. 1995. Virulence ranking of some Mycobacterium tuberculosis and Mycobacterium bovis strains according to their ability to multiply in lungs, induce lung pathology, and cause mortality in mice. Infect. Immun. 63:3428-3437.
13. Flesch, I., and S. H. E. Kaufmann. 1987. Mycobacterial growth inhibition by interferon-γ-activated bone marrow macrophages and differential susceptibility among strains of Mycobacterium tuberculosis. J. Immunol. 138:4408-4413.
14. Flynn, J. L., J. Chan, K. J. Triebold, D. K. Dalton, T. A. Stewart, and B. A. Bloom. 1993. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249-2254.
15. + T-cell subsets following infection of naive and memory immune mice with Mycobacterium tuberculosis. Infect, Immun. 62:1683-1690.
16. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389:737-742.
17. Hernandez-Pando, R., E. H. Orozco, A. Sampieri, L. Pavon. C. Velasquillo, J. Larriva-Sahol, J. M. Alcocer, and M. V. Madrid 1996. Correlation between the kinetics of Th-1/Th-2 cells and pathology in a murine model of experimental pulmonary tuberculosis. Immunology 89:26-33.
18. Hernandez-Pando, R., L. Pavon, K. Arriaga, H. Orozco, V. Madrid-Marina, and G. Rook. 1997. Pathogenesis of tuberculosis in mice exposed to low and high doses of an environmental mycobacterial saprophyte before infection. Infect. Immun. 65:3317-3327.
19. Merry, I., M. Bonay, F. Bouchonnet, M. P. Schuller, D. Lecossier, A. Tazi, D. H. Lynch, and A. J. Hance. 1996. Extensive apoptosis of lung T-lymphocytes maintained in vitro. Am. J. Respir. Cell. Mol. Biol. 15:339-347.
20. Holt, P. G. 1986. Downregulation of immune responses in the lower respiratory tract: the role of alveolar macrophages. Clin. Exp. Immunol. 63:261-270.
21. Holt, P. G., A. Degebrodt, C. O'Leary, K. Krska. and T. Plozza. 1985. T cell activation by antigen-presenting cells from lung tissue digests: suppression by endogenous macrophages. Clin. Exp. Immunol. 62:586-591
22. Holt, P. G., U. R. Kees, M. A. Shon-Hegrad, A. Rose, J. Ford, J. Bilyk, N. Bilyk, R. Bowman, and B. W. S. Robinson. 1988. Limiting-dilution analysis of T cells extracted from solid human lung tissue: comparison of precursor frequencies for proliferative responses and lymphokine production between lung and blood T cells from individual donors. Immunology 64:649-654.
23. Kondratieva, T. K., N. V. Kobets, S. V. Khaidukov, V. V. Yeremeev, I. V. Lyadova, A. S. Apt, M. F. Tarn, and M. M. Stevenson. Characterisation of T-cell clones derived from lymph nodes and lungs of Pseudomonas aeruginosa-susceptible and resistant mouse strains. Submitted for publication.
24. Lee, W. T., and E. S. Vitetta. 1991. The differential expression of homing and adhesion molecules on virgin and memory T cells in the mouse. Cell. Immumol. 132:215-222.
25. + T cells. J. Immunol. 144:3288-3295.
26. Lenzini, L., P. Rottoli, and L. Rottoli. 1977. The spectrum of human tuberculosis. Clin. Exp. Immunol, 27:230-237.
27. Mbawuike, I. N., and H. B. Herseowitz. 1988. Role of activation in alveolar macrophage-mediated suppression of the plaque-forming cell response. Infect, Immun, 56:577-582.
28. McCombs, C. C., J. P. Michalski, B. T. Westerfleld, and R. W. Light. 1982. Human alveolar macrophages suppress the proliferate response of peripheral blood lymphocytes. Chest 82:266-271.
29. McLeod, R., E. Buschman, L. D. Arbuckle, and E. Skamene. 1995. Imnunogenetics in the analysis of resistance to intracellular pathogens. Curr. Opin. Immunol. 7:539-552.
30. Nikonenko, B. V., A. S. Apt, M. B. Mezhlumuva, V. G. Avdienko, V. V. Yeremeev, and A. M. Moroz. 1996. Influence of the mouse Beg, Tbc-1 and xid genes on resistance and immune responses to tuberculosis infection and efficacy of BCG vaccination, Clin. Exp. Immunol. 104:37-43.
31. Nikonenko. B. V., A. S. Apt, A. M. Moroz, and M. M. Averbakh. 1985. Genetic analysis of susceptibility of mice to H37Rv tuberculosis infection: sensitivity versus relative resistance, p. 291-298. In E. Skamene (ed.), Genetic control of host resistance to infection and malignancy. Alan R. Liss, Inc., New York, N.Y.
32. North, R. J., and A. A. Izzo. 1993. Mycobacterial virulence. Virulent strains of Mycobacterium tuberculosis have faster in vivo doubling times and are better equipped to resist growth-inhibiting functions of macrophages in the presence and absence of specific immunity. J. Exp. Med. 177:1723-1733.
33. Orme, I. M., P. Andersen, and W. H. Boom, 1993. T cell response to Mycobacterium tuberculosis. J. Infect. Dis. 167:1481-1497.
34. Rook, G. A. W., B. R. Champion, J. Steele, A. M. Varey, and J. L. Stanford. 1985. I-A restricted activation by T cell lines of anti-tuberculosis activity in murine macrophages. Clin. Exp. Immunol, 59:414-420.
35. Rook, G. A. W., and R. Hernandez-Pando. 1996. The pathogenesis of tuberculosis. Annu. Rev. Microbiol. 50:259-284.
36. Rook, G. A. W., J. Steele, M. Ainsworth, and B. R. Champion. 1986. Activation of macrophages to inhibit proliferation of Mycobacterium tuberculosis: comparison of the effects of recombinant gamma-interferon on human monocytes and murine peritoneal macrophages. Immunology 59:333-338.
37. Silva, C. L., M. F. Silva, R. C. L. R. Pietro, and D. B. Lowrie. 1996. Characterization of T cells that confer a high degree of protective immunity against tuberculosis in mice after vaccination with tumor cells expressing mycobacterial hsp65. Infect. Immun. 64:2400-2407.
38. Stach, J. L., P. Gros, A. Forget, and E. Skamene. 1984. Phenotypic expression of genetically controlled natural resistance to Mycobacterium bovis (BCG). J. Immunol. 132:883-892.
39. Stevenson, M. M., T. K. Kondratieva, A. S. Apt, M. F. Tam, and E. Skamene. 1995. In vitro and in vivo T cell responses in mice during bronchopulmonary infection with mucoid Pseudomonas aeruginosa. Clin. Exp. Immunol. 99:98-105.
40. Strickland, D., U. R. Kees, and P. G. Holt. 1996. Regulation of T-cell activation in the lung: isolated lung T cells exhibit surface phenotypic characteristics of recent activation including down-modulated T-cell receptors, but are locked into the G0/G1 phase of the cell cycle. Immunology 87:242-249.
41. Strickland, D., U. R. Kees, and P. G. Holt. 1996. Regulation of T-cell activation in the lung: alveolar macrophages induce reversible T-cell anergy in vitro associated with inhibition of interleukin-2 receptor signal transduction. Immunology 87:250-258.
42. Strickland, D., T. Thepen, U. R. Kees, G. Kraal and P. G. Holt. 1993. Regulation of T-cell function in lung tissue by pulmonary alveolar macrophages. Immunology 80:266-272.