Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 7, 2013, Pages 2079-2087

  Mizuhara, Tsukasa ^a   Oishi, Shinya ^a   Ohno, Hiroaki ^a   Shimura, Kazuya ^a   Matsuoka, Masao ^a   Fujii, Nobutaka ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Anti HIV agents; PD 404182; Photoaffinity labeling; Pyrimidobenzothiazine

Indexed keywords

3,4 DIHYDRO 2H,6H PYRIMIDO[1,2 C][1,3]BENZOTHIAZIN 6 IMINE; ALKYNE DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BIOTIN DERIVATIVE; PD 404182; PYRIMIDOBENZOTHIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PHOTOAFFINITY LABELING; STRUCTURE ACTIVITY RELATION; SYNTHESIS; VIRUS CELL INTERACTION;

ALKYNES; ANTI-HIV AGENTS; BIOTIN; CELL LINE; HIV INFECTIONS; HIV-1; HUMANS; PHOTOAFFINITY LABELS; PROTEIN BINDING; VIRAL PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84875217288     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.01.016     Document Type: Article

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