Binding of multivalent anionic porphyrins to V3 loop fragments of an HIV-1 envelope and their antiviral activity

Chemistry - An Asian Journal

Volumn 5, Issue 4, 2010, Pages 825-834

  Watanabe, Kenji ^a   Negi, Shigeru ^b   Sugiura, Yukio ^b   Kiriyama, Akiko ^b   Honbo, Akino ^b   Iga, Katsumi ^b   Kodama, Eiichi N ^c   Naitoh, Takeshi ^c   Matsuoka, Masao ^c   Kano, Koji ^a  

^a DOSHISHA UNIVERSITY   (Japan)

^b DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Antiviral agents; Electrostatic interactions; Inhibitors; Porphyrinoids; Proteins

Indexed keywords

ANIONIC GROUPS; ANTI-HIV; ANTI-HIV ACTIVITY; ANTIVIRAL ACTIVITIES; ANTIVIRAL AGENTS; AQUEOUS SOLUTIONS; BINDING CONSTANT; CATIONIC PEPTIDES; CIRCULAR DICHROISM; COMPLEX STABILIZATION; ELECTROSTATIC INTERACTIONS; ENVELOPE PROTEINS; EPR SPECTROSCOPY; FERRIC COMPLEXES; GALACTOSIDASES; HALF LIVES; HIGH SELECTIVITY; INHIBITORS; IRON CENTERS; IRON PORPHYRIN; LOOP REGIONS; LOW CONCENTRATIONS; MICROCALORIMETRIC TITRATION; MODEL SYSTEM; NUCLEAR ACTIVATION; PHARMACOKINETIC STUDIES; PORPHYRINOIDS; SELF-AGGREGATES; SERUM ALBUMIN; STABLE COMPLEXES; STRONG INTERACTION; TETRAKIS; VAN DER WAALS INTERACTIONS; WISTAR RAT;

BARIUM; BODY FLUIDS; COORDINATION REACTIONS; DICHROISM; DYES; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTROSTATICS; IRON COMPOUNDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARAMAGNETIC RESONANCE; PEPTIDES; PORPHYRINS; TITRATION; VAN DER WAALS FORCES; VIRUSES;

COMPLEXATION;

ANION; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; COORDINATION COMPOUND; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; IRON; PORPHYRIN;

ANIMAL; ARTICLE; CHEMISTRY; HELA CELL; HUMAN; MALE; PROTEIN TERTIARY STRUCTURE; RAT; SYNTHESIS; THERMODYNAMICS; WISTAR RAT;

ANIMALS; ANIONS; ANTI-HIV AGENTS; COORDINATION COMPLEXES; HELA CELLS; HIV ENVELOPE PROTEIN GP120; HIV FUSION INHIBITORS; HUMANS; IRON; MALE; PORPHYRINS; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, WISTAR; THERMODYNAMICS;

EID: 77950827325     PISSN: 18614728     EISSN: 1861471X     Source Type: Journal    
DOI: 10.1002/asia.200900465     Document Type: Article

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