Characterization of a binding site for template competitive inhibitors of HIV-1 reverse transcriptase using photolabeling derivatives

Bioorganic and Medicinal Chemistry

Volumn 10, Issue 12, 2002, Pages 4131-4141

  Lin, Weiying ^a   Li, Ke ^a   Doughty, Michael B ^a,b  

^a UNIVERSITY OF KANSAS   (United States)

^b SOUTHEASTERN LOUISIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3H DIAZEPINON 4 YL)THIO 1,N6 ETHENODEOXYADENOSINE PHOSPHATE; 2 (4 AZIDO 2,3,5,6 TETRAFLUOROPHENACYL)THIO 1,N6 ETHENO 2' DEOXYADENOSINE 5' TRIPHOSPHATE; 2 (4 AZIDOPHENACYL)THIO 1,N6 ETHENO 2' DEOXYADENOSINE 5' TRIPHOSPHATE; AMMONIUM 2 (3H DIAZEPINION 4 YL)THIO 1,N6 ETHENODEOXYADENOSINE PHOSPHATE; AMMONIUM 2 (4 AMINOPHENACYL)THIO 1,N6 ETHENODEOXYADENOSINE PHOSPHATE; DEOXYADENOSINE PHOSPHATE; DEOXYADENOSINE TRIPHOSPHATE; PHOSPHORUS 32; PROTEIN P66; PROTEIN SUBUNIT; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; HALF LIFE TIME; HUMAN IMMUNODEFICIENCY VIRUS 1; ISOTOPE LABELING; PHOTOAFFINITY LABELING; PHOTODEGRADATION; PHOTOLYSIS;

ADENOSINE TRIPHOSPHATE; BINDING SITES; BINDING, COMPETITIVE; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; PEPTIDE MAPPING; PHOTOAFFINITY LABELS; PHOTOLYSIS; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; ULTRAVIOLET RAYS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0036973291     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00259-6     Document Type: Article

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