Regulating the ARNT/TACC3 axis: Multiple approaches to manipulating protein/protein interactions with small molecules

ACS Chemical Biology

Volumn 8, Issue 3, 2013, Pages 626-635

  Guo, Yirui ^a,b   Partch, Carrie L ^a,b,d   Key, Jason ^a,b   Card, Paul B ^a,b   Pashkov, Victor ^b   Patel, Anjana ^c   Bruick, Richard K ^b   Wurdak, Heiko ^c   Gardner, Kevin H ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1BETA; TRANSCRIPTION FACTOR; TRANSFORMING ACIDIC COILED COIL CONTAINING PROTEIN 3; UNCLASSIFIED DRUG; ARNT PROTEIN, HUMAN; KHS101; MICROTUBULE ASSOCIATED PROTEIN; MOLECULAR LIBRARY; PROTEIN BINDING; TACC3 PROTEIN, HUMAN; THIAZOLE DERIVATIVE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SPACE; LIGAND BINDING; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; STEM CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; HEK293 CELL LINE; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; RAT; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, MOLECULAR; PROTEIN BINDING; RATS; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 84875201642     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300604u     Document Type: Article

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