Divergent expression of L-type amino acid transporter 1 during uterine cervical carcinogenesis

Human Pathology

Volumn 42, Issue 11, 2011, Pages 1660-1666

  Uno, Kaname ^a   Kuwabara, Haruki ^a   Terado, Yuichi ^a   Kojima, Kaoruko ^a   Kawakami, Tomohiro ^b   Kamma, Hiroshi ^a   Sakurai, Hiroyuki ^a   Sakamoto, Atsuhiko ^a   Kurata, Atsushi ^a  

^a KYORIN UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

Author keywords

Differential diagnosis; Human papillomavirus; L type amino acid transporter 1; Uterine cervical neoplasm

Indexed keywords

BIOLOGICAL MARKER; EXCITATORY AMINO ACID TRANSPORTER 1; I TYPE AMINO ACID TRANSPORTER 1; KI 67 ANTIGEN; PROTEIN P16; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INVASIVE CARCINOMA; PAPILLOMAVIRUS INFECTION; PROTEIN EXPRESSION; UTERINE CERVIX CARCINOMA; UTERINE CERVIX DYSPLASIA; UTERINE CERVIX MUCOSA;

ADENOCARCINOMA; CARCINOMA, SQUAMOUS CELL; CERVICAL INTRAEPITHELIAL NEOPLASIA; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; LARGE NEUTRAL AMINO ACID-TRANSPORTER 1; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS;

EID: 80054693918     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2011.01.013     Document Type: Article

References (34)

1. Kanai Y., Segawa H., and Miyamoto K. Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98) J Biol Chem 273 1998 23629 23632 (Pubitemid 28435687)
2. Yoon J.H., Kim Y.B., and Kim M.S. Expression and functional characterization of the system L amino acid transporter in KB human oral epidermoid carcinoma cells Cancer Lett 205 2004 215 226 (Pubitemid 38230129)
3. Storey B.T., Fugere C., and Lesieur-Brooks A. Adenoviral modulation of the tumor-associated system L amino acid transporter, LAT1, alters amino acid transport, cell growth and 4F2/CD98 expression with cell-type specific effects in cultured hepatic cells Int J Cancer 117 2005 387 397 (Pubitemid 41429562)
4. Yanagida O., Kanai Y., and Chairoungdua A. Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines Biochim Biophys Acta 1514 2001 291 302 (Pubitemid 32831016)
5. Kobayashi H., Ishii Y., and Takayama T. Expression of L-type amino acid transporter 1 (LAT1) in esophageal carcinoma J Surg Oncol 90 2005 233 238 (Pubitemid 40770938)
6. Kim D.K., Ahn S.G., and Park J.C. Expression of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in oral squamous cell carcinoma and its precusor lesions Anticancer Res 24 2004 1671 1675 (Pubitemid 38954693)
7. Park K.J., and Soslow R.A. Current concepts in cervical pathology Arch Pathol Lab Med 133 2009 729 738
8. Kalof A.N., and Cooper K. Our approach to squamous intraepithelial lesions of the uterine cervix J Clin Pathol 60 2007 449 455 (Pubitemid 46867149)
9. Wells M., Ostor A.G., and Crum C.P. Epithelial tumours F.A. Tavassoli, World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs 2003 IARC Press Lyon 260 279
10. Chairoungdua A., Segawa H., and Kim J.Y. Identification of an amino acid transporter associated with the cystinuria-related type II membrane glycoprotein J Biol Chem 274 1999 28845 28848
11. Nawashiro H., Otani N., and Shinomiya N. L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors Int J Cancer 119 2006 484 492 (Pubitemid 43955699)
12. Sakata T., Ferdous G., and Tsuruta T. L-type amino-acid transporter 1 as a novel biomarker for high-grade malignancy in prostate cancer Pathol Int 59 2009 7 18
13. Iaconis L., Hyjek E., and Ellenson L.H. p16 and Ki-67 immunostaining in atypical immature squamous metaplasia of the uterine cervix: correlation with human papillomavirus detection Arch Pathol Lab Med 131 2007 1343 1349 (Pubitemid 47427587)
14. Yoon J.H., Kim I.J., and Kim H. Amino acid transport system L is differently expressed in human normal oral keratinocytes and human oral cancer cells Cancer Lett 222 2005 237 245 (Pubitemid 40603651)
15. Benevolo M., Terrenato I., and Mottolese M. Comparative evaluation of nm23 and p16 expression as biomarkers of high-risk human papillomavirus infection and cervical intraepithelial neoplasia 2(+) lesions of the uterine cervix Histopathology 57 2010 580 586
16. Ganapathy V., Thangaraju M., and Prasad P.D. Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond Pharmacol Ther 121 2009 29 40
17. Kaira K., Oriuchi N., and Imai H. Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I-III nonsmall cell lung cancer Br J Cancer 98 2008 742 748 (Pubitemid 351272621)
18. Kaira K., Oriuchi N., and Imai H. Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma Lung Cancer 66 2009 120 126
19. Yamauchi K., Sakurai H., and Kimura T. System L amino acid transporter inhibitor enhances anti-tumor activity of cisplatin in a head and neck squamous cell carcinoma cell line Cancer Lett 276 2009 95 101
20. Ohkame H., Masuda H., and Ishii Y. Expression of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in liver tumor lesions of rat models J Surg Oncol 78 2001 265 272
21. Singh R.K., and Siegal G.P. Amino acid transport systems modulate human tumor cell growth and invasion: a working hypothesis Med Hypotheses 44 1995 195 201
22. Shikano N., Ogura M., and Okudaira H. Uptake of 3-[125I]iodo-alpha- methyl-L-tyrosine into colon cancer DLD-1 cells: characterization and inhibitory effect of natural amino acids and amino acid-like drugs Nucl Med Biol 37 2010 197 204
23. Kaira K., Oriuchi N., and Imai H. l-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms Cancer Sci 99 2008 2380 2386
24. Imai H., Kaira K., and Oriuchi N. L-type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non-small cell lung cancer Histopathology 54 2009 804 813
25. Kaira K., Oriuchi N., and Shimizu K. Evaluation of thoracic tumors with (18)F-FMT and (18)F-FDG PET-CT: a clinicopathological study Int J Cancer 124 2009 1152 1160
26. Travers M.T., Gow I.F., and Barber M.C. Indoleamine 2,3-dioxygenase activity and L-tryptophan transport in human breast cancer cells Biochim Biophys Acta 1661 2004 106 112 (Pubitemid 38201576)
27. Nakanishi K., Ogata S., and Matsuo H. Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract Virchows Arch 451 2007 681 690 (Pubitemid 47340986)
28. Tamai S., Masuda H., and Ishii Y. Expression of L-type amino acid transporter 1 in a rat model of liver metastasis: positive correlation with tumor size Cancer Detect Prev 25 2001 439 445
29. Kaira K., Oriuchi N., and Imai H. L-type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas J Surg Oncol 99 2009 433 438
30. Nawashiro H., Otani N., and Uozumi Y. High expression of L-type amino acid transporter 1 in infiltrating glioma cells Brain Tumor Pathol 22 2005 89 91 (Pubitemid 44576318)
31. Kobayashi K., Ohnishi A., and Promsuk J. Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells Neurosurgery 62 2008 493 504
32. Shennan D.B., and Thomson J. Inhibition of system L (LAT1/CD98hc) reduces the growth of cultured human breast cancer cells Oncol Rep 20 2008 885 889
33. Baniasadi S., Chairoungdua A., and Iribe Y. Gene expression profiles in T24 human bladder carcinoma cells by inhibiting an L-type amino acid transporter, LAT1 Arch Pharm Res 30 2007 444 452
34. Kaira K., Oriuchi N., and Otani Y. Fluorine-18-alpha-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer: a clinicopathologic study Clin Cancer Res 13 2007 6369 6378 (Pubitemid 350075026)