West African Sorghum bicolor leaf sheaths have anti-inflammatory and immune-modulating properties in vitro

Journal of Medicinal Food

Volumn 16, Issue 3, 2013, Pages 230-238

  Benson, Kathleen F ^a   Beaman, Joni L ^a   Ou, Boxin ^b   Okubena, Ademola ^c   Okubena, Olajuwon ^c   Jensen, Gitte S ^a  

^a NIS Labs   (United States)

^b Dover Sciences   (United States)

^c Health Forever Products Inc   (Nigeria)

Author keywords

CD69; Leukotriene B4; Migration; Monocytes; Natural killer cells; Peripheral blood mononuclear cells; Polymorphonuclear cells; ROS formation; T cells

Indexed keywords

ALCOHOL; ANTIINFLAMMATORY AGENT; CD3 ANTIGEN; CD56 ANTIGEN; CD69 ANTIGEN; IMMUNOMODULATING AGENT; INTERLEUKIN 6; LEUKOTRIENE B4; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; POLYPHENOL DERIVATIVE; RANTES; REACTIVE OXYGEN METABOLITE; SORGHUM BICOLOR EXTRACT; UNCLASSIFIED DRUG;

AFRICA; ANTIINFLAMMATORY ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BIOLOGICAL ACTIVITY; CD3+ T LYMPHOCYTE; CELL ACTIVATION; CELL FUNCTION; CELL MIGRATION; CELL PROTECTION; CELL SUBPOPULATION; CELL SURFACE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOMODULATION; IN VITRO STUDY; LEAF SHEATH; LYMPHOCYTE; MONOCYTE; MONONUCLEAR CELL; NATURAL KILLER CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; SORGHUM; UPREGULATION;

AFRICA, WESTERN; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD; CELL MOVEMENT; CHEMOKINE CCL3; CHEMOKINE CCL4; CHEMOKINE CCL5; CHEMOTACTIC FACTORS; HUMANS; IMMUNOLOGIC FACTORS; INFLAMMATION; KILLER CELLS, NATURAL; LEUKOCYTES, MONONUCLEAR; LEUKOTRIENE B4; MONOCYTES; PLANT EXTRACTS; PLANT LEAVES; POLYPHENOLS; REACTIVE OXYGEN SPECIES; SORGHUM; T-LYMPHOCYTES; UP-REGULATION;

EID: 84875139190     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2012.0214     Document Type: Article

References (36)

1. Kanterman J, Sade-Feldman M, Baniyash M: New insights into chronic inflammation-induced immunosuppression. Semin Cancer Biol 2012;22: 307-318
2. Elenkov IJ, Iezzoni DG, Daly A, Harris AG, Chrousos GP: Cytokine dysregulation, inflammation and well-being. Neuroimmunomodulation 2005;12: 255-269 (Pubitemid 41318209)
3. Elenkov IJ: Neurohormonal-cytokine interactions: Implications for inflammation, common human diseases and well-being. Neurochem Intl 2008;52: 40-51 (Pubitemid 350235704)
4. de Heredia FP, Go'mez-Marti'nez S, Marcos A: Obesity, inflammation and the immune system. Proc Nutr Soc 2012;71: 332-338
5. Dall'Asta M, Derlindati E, Ardigo D, Zavaroni I, Brighenti F, Del Rio DM: Macrophage polarization: The answer to the diet/ inflammation conundrum? Nutr Metab Cardiovasc Dis 2012; 22: 387-392
6. Dykes L, Rooney LW: Sorghum and millet phenols and antioxidants. Review. J Cereal Sci 2006;44: 236-251 (Pubitemid 44693119)
7. Devi PS, Kumar MS, Das SM: Evaluation of antiproliferative activity of red sorghum bran anthocyanin on a human breast cancer cell line (mcf-7). Int J Breast Cancer 2011;2011: 891481
8. Bröhan M, Jerkovic V, Collin S: Potentiality of red sorghum for producing stilbenoid-enriched beers with high antioxidant activity. J Agric Food Chem 2011;59: 4088-4094
9. Mueller-Harvey I, Reed JD: Identification of phenolic compounds and their relationships to in-vitro digestibility of sorghum leaves from bird-resistant and non-bird-resistant varieties. J Sci Food Agric 1992;60: 179-196
10. Kayode APP, Nout MJR, Linnemann AR, Joseph D, Hounhouigan JD, Berghofer E, Siebenhandl-Ehn S: Uncommonly high levels of 3-deoxyanthocyanidins and antioxidant capacity in the leaf sheaths of dye sorghum. J Agric Food Chem 2011;59: 1178
11. Geera B, Ojwang LO, Awika JM: New highly stable dimeric 3- deoxyanthocyanidin pigments from Sorghum bicolor leaf sheath. J Food Sci 2012;77: C566-C572
12. Yang L, Browning JD, Awika JM: Sorghum 3-deoxyanthocyanins possess strong phase II enzyme inducer activity and cancer cell growth inhibition properties. J Agric Food Chem 2009;57: 1797
13. Shih C-H, Siu S-O, Ng R, Wong E, Chiu LCM, Chu IK, Lo C: Quantitative analysis of anticancer 3-deoxyanthocyanidins in infected sorghum seedlings. J Agric Food Chem 2007;55: 254
14. Ramesh HP, Tharanathan RN: Non-cellulosic mixed linkage beta-D-glucan in sorghum, Sorghum bicolor (L.) Moench -
15. localization and biological activity studies. Indian J Exp Biol 2000;38: 155-159
16. Camargo Filho I, Cortez DA, Ueda-Nakamura T, Nakamura CV, Dias Filho BP: Antiviral activity and mode of action of a peptide isolated from Sorghum bicolor. Phytomedicine 2008;15: 202
17. Erah Patrick O, AsonyeCanice C, Okhamaf Augustine O: Response of Trypanosoma brucei brucei-induced anaemia to a commercial herbal preparation. Afr J Biotechnol 2003;2: 307-311
18. Oladiji AT, Jacob TO, Yakubu MT: Anti-anaemic potentials of aqueous extract of Sorghum bicolor (L.) Moench stem bark in rats. J Ethnopharmacol 2007;111: 651-656 (Pubitemid 46621140)
19. Akande IS, Oseni AA, Biobaku OA: Effects of aqueous extract of Sorghum bicolor on hepatic, histological and haematological indices in rats. J Cell Animal Biol 2010;4: 137-142
20. Ogwumike OO: Hemopoietic effect of aqueous extract of the leaf sheath of Sorghum bicolor in albino rats. Afr J Biomed Res 2002;5: 69-71
21. Nwinyi FC, Kwanashie HO: Evaluation of aqueous methanolic extract of Sorghum bicolor leaf base for antinociceptive and antiinflammatory activities. Afr J Biotechnol 2009;8: 4642-4649
22. Honzel D, Carter SG, Redman KA, Schauss AG, Endres JR, Jensen GS: Comparison of chemical and cell-based antioxidant methods for evaluation of foods and natural products: Generating multifaceted data by parallel testing using erythrocytes and polymorphonuclear cells. J Agric Food Chem 2008;56: 8319-8325
23. Jensen GS, Patterson KM, Yoon I: Yeast culture has antiinflammatory effects and specifically activates NK cells. Comp Immunol Microbiol Infect Dis 2008;31: 487-500
24. Jensen GS, Benson KF, Carter SG, Endres JR: GanedenBC30 cell wall and metabolites: Anti-inflammatory and immune modulating effects in vitro. BMC Immunol 2010;24: 11: 15
25. Clausen J, Vergeiner B, Enk M, Petzer AL, Gastl G, Gunsilius E: Functional significance of the activation-associated receptors CD25 and CD69 on human NK-cells and NK-like T-cells. Immunobiology 2003;207: 85-93 (Pubitemid 36367381)
26. Burdette A, Garner PL, Mayer EP, Hargrove JL, Hartle DK, Greenspan P: Anti-inflammatory activity of select sorghum (Sorghum bicolor) brans J Med Food 2010;13: 879-887
27. USDA Database for the Oxygen Radical Absorbance Capacity (ORAC) of Selected Foods, Release 2, U.S. Department of Agriculture, 2010
28. Kang J, Li Z, Wu T, Jensen GS, Schauss AG, Wu X: Antioxidant capacities of flavonoid compounds isolated from acai pulp (Euterpe oleracea Mart.). Food Chem 2010;122: 610-617
29. Kang J, Thakali KM, Xie C, Kondo M, Tong Y, Ou B, Jensen GS, Medina MB, Schauss AG, Wu X: Bioactivities of açaí (Euterpe precatoria Mart.) fruit pulp, superior antioxidant and anti-inflammatory properties to Euterpe oleracea Mart. Food Chem 2012;133: 671-677
30. Park JH, Darvin P, Lim EJ, Joung YH, Hong DY, Park EU, Park SH, Choi SK, Moon ES, Cho BW, Park KD, Lee HK, Kim MJ, Park DS, Chung IM, Yang YM: Hwanggeumchal sorghum induces cell cycle arrest, and suppresses tumor growth and metastasis through jak2/stat pathways in breast cancer xenografts. PLoS One 2012;7: E40531
31. Wu L, Huang Z, Qin P, Yao Y, Meng X, Zou J, Zhu K, Ren G: Chemical characterization of a procyanidin-rich extract from sorghum bran and its effect on oxidative stress and tumor inhibition in vivo. J Agric Food Chem 2011;59: 8609-8615
32. Mesiano G, Todorovic M, Gammaitoni L, Leuci V, Giraudo Diego L, Carnevale-Schianca F, Fagioli F, Piacibello W, Aglietta M, Sangiolo D: Cytokine-induced killer (CIK) cells as feasible and effective adoptive immunotherapy for the treatment of solid tumors. Expert Opin Biol Ther 2012;12: 673-684
33. Saikh KU, Dyas B, Kissner T, Ulrich RG: CD56 + -T-cell responses to bacterial superantigens and immune recognition of attenuated vaccines. Clin Diagn Lab Immunol 2003;10: 1065
34. Delneste Y, Charbonnier P, Herbault N, Magistrelli G, Caron G, Bonnefoy JY, Jeannin P: Interferon-gamma switches monocyte differentiation from dendritic cells to macrophages. Blood 2003; 101: 143-150 (Pubitemid 36025900)
35. De Maria R, Cifone MG, Trotta R, Rippo MR, Festuccia C, Santoni A, Testi R: Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors. J Exp Med 1994;180: 1999-2004 (Pubitemid 24328594)
36. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P: Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8 + T cells. Science 1995;270: 1811-1815