Mechanistic basis of the inhibition of type II dehydroquinase by (2 S)- and (2 R)-2-benzyl-3-dehydroquinic acids

ACS Chemical Biology

Volumn 8, Issue 3, 2013, Pages 568-577

  Lence, Emilio ^a   Tizón, Lorena ^a   Otero, José M ^b   Peón, Antonio ^a   Prazeres, Verónica F V ^a   Llamas Saiz, Antonio L ^b   Fox, Gavin C ^c   Van Raaij, Mark J ^d   Lamb, Heather ^e   Hawkins, Alastair R ^e   González Bello, Concepción ^a  

^a s n   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c SYNCHROTRON SOLEIL   (France)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 METHOXY)BENZYL 2 PERFLUOROBENZYL 3 DEHYDROQUINIC ACID; 2 (BENZOTHIOPHEN 5 YL)METHYL 3 DEHYDROQUINIC ACID; 2 BENZYL 3 DEHYDROQUINIC ACID; ARGININE; ASPARAGINE; BENZYL DERIVATIVE; LEUCINE; LYASE; TRYPTOPHAN; TYPE II DEHYDROQUINASE; UNCLASSIFIED DRUG; 2-BENZYL-3-DEHYDROQUINIC ACID; 3-DEHYDROQUINATE DEHYDRATASE; ENZYME INHIBITOR; HYDROLYASE; QUINIC ACID;

ARTICLE; CATALYSIS; CRYSTALLIZATION; ELECTRON TRANSPORT; ENZYME INHIBITION; ENZYME STRUCTURE; HELICOBACTER PYLORI; HYDROGEN BOND; LIGAND BINDING; MOLECULAR DYNAMICS; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; SIMULATION; STATIC ELECTRICITY; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; METABOLISM; SYNTHESIS;

ENZYME INHIBITORS; HELICOBACTER PYLORI; HYDRO-LYASES; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; QUINIC ACID;

EID: 84875130798     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300493s     Document Type: Article

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