-
1
-
-
0028588064
-
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
-
Dec 16
-
Chang Y, Cesarman E, Pessin MS, et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science. 1994 Dec 16;266(5192):1865-1869.
-
(1994)
Science
, vol.266
, Issue.5192
, pp. 1865-1869
-
-
Chang, Y.1
Cesarman, E.2
Pessin, M.S.3
-
2
-
-
0034611717
-
Kaposi's sarcoma
-
Apr 6
-
Antman K, Chang Y. Kaposi's sarcoma. N Engl J Med. 2000 Apr 6;342(14):1027-1038.
-
(2000)
N Engl J Med.
, vol.342
, Issue.14
, pp. 1027-1038
-
-
Antman, K.1
Chang, Y.2
-
3
-
-
0029069445
-
Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas
-
May 4
-
Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med. 1995 May 4;332(18):1186-1191.
-
(1995)
N Engl J Med.
, vol.332
, Issue.18
, pp. 1186-1191
-
-
Cesarman, E.1
Chang, Y.2
Moore, P.S.3
Said, J.W.4
Knowles, D.M.5
-
4
-
-
0029166033
-
Kaposi's sarcomaassociated herpesvirus-like DNA sequences in multicentric Castleman's disease
-
Aug 15
-
Soulier J, Grollet L, Oksenhendler E, et al. Kaposi's sarcomaassociated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood. 1995 Aug 15;86(4):1276-1280.
-
(1995)
Blood
, vol.86
, Issue.4
, pp. 1276-1280
-
-
Soulier, J.1
Grollet, L.2
Oksenhendler, E.3
-
5
-
-
0028835074
-
Kaposi's sarcomaassociated herpesvirus infects endothelial and spindle cells
-
Dec
-
Boshoff C, Schulz TF, Kennedy MM, et al. Kaposi's sarcomaassociated herpesvirus infects endothelial and spindle cells. Nat Med. 1995 Dec;1(12):1274-1278.
-
(1995)
Nat Med.
, vol.1
, Issue.12
, pp. 1274-1278
-
-
Boshoff, C.1
Schulz, T.F.2
Kennedy, M.M.3
-
6
-
-
77951736609
-
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor: Lessons on dysregulated angiogenesis from a viral oncogene
-
May
-
Jham BC, Montaner S. The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor: lessons on dysregulated angiogenesis from a viral oncogene. J Cell Biochem. 2010 May; 110(1):1-9.
-
(2010)
J Cell Biochem.
, vol.110
, Issue.1
, pp. 1-9
-
-
Jham, B.C.1
Montaner, S.2
-
7
-
-
0031937076
-
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator
-
Jan 1, Erratum in: Nature. 1998 Mar 12;392(6672):210
-
Bais C, Santomasso B, Coso O, et al. G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature. 1998 Jan 1;391(6662):86-89 Erratum in: Nature. 1998 Mar 12;392(6672):210.
-
(1998)
Nature
, vol.391
, Issue.6662
, pp. 86-89
-
-
Bais, C.1
Santomasso, B.2
Coso, O.3
-
8
-
-
0037320031
-
Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse
-
Feb
-
Guo HG, Sadowska M, Reid W, Tschachler E, Hayward G, Reitz M. Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse. J Virol. 2003 Feb;77(4):2631-2639.
-
(2003)
J Virol.
, vol.77
, Issue.4
, pp. 2631-2639
-
-
Guo, H.G.1
Sadowska, M.2
Reid, W.3
Tschachler, E.4
Hayward, G.5
Reitz, M.6
-
9
-
-
0037772150
-
Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes
-
Jan
-
Montaner S, Sodhi A, Molinolo A, et al. Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell. 2003 Jan;3(1):23-36.
-
(2003)
Cancer Cell.
, vol.3
, Issue.1
, pp. 23-36
-
-
Montaner, S.1
Sodhi, A.2
Molinolo, A.3
-
10
-
-
0034614888
-
Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma
-
Feb 7
-
Yang TY, Chen SC, Leach MW, et al. Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma. J Exp Med. 2000 Feb 7;191(3):445-454.
-
(2000)
J Exp Med.
, vol.191
, Issue.3
, pp. 445-454
-
-
Yang, T.Y.1
Chen, S.C.2
Leach, M.W.3
-
11
-
-
0142213135
-
Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR
-
Feb
-
Bais C, Van Geelen A, Eroles P, et al. Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR. Cancer Cell. 2003 Feb;3(2):131-143.
-
(2003)
Cancer Cell.
, vol.3
, Issue.2
, pp. 131-143
-
-
Bais, C.1
van Geelen, A.2
Eroles, P.3
-
12
-
-
1542313867
-
Does dysregulated expression of a deregulated viral GPCR trigger Kaposi's sarcomagenesis?
-
Mar
-
Sodhi A, Montaner S, Gutkind JS. Does dysregulated expression of a deregulated viral GPCR trigger Kaposi's sarcomagenesis? FASEB J. 2004 Mar;18(3):422-427.
-
(2004)
FASEB J.
, vol.18
, Issue.3
, pp. 422-427
-
-
Sodhi, A.1
Montaner, S.2
Gutkind, J.S.3
-
13
-
-
0034282553
-
The Kaposi's sarcomaassociated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha
-
Sep 1
-
Sodhi A, Montaner S, Patel V, et al. The Kaposi's sarcomaassociated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha. Cancer Res. 2000 Sep 1;60(17):4873-4880.
-
(2000)
Cancer Res.
, vol.60
, Issue.17
, pp. 4873-4880
-
-
Sodhi, A.1
Montaner, S.2
Patel, V.3
-
14
-
-
0035866812
-
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B
-
Mar 15
-
Montaner S, Sodhi A, Pece S, Mesri EA, Gutkind JS. The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B. Cancer Res. 2001 Mar 15;61(6):2641-2648.
-
(2001)
Cancer Res.
, vol.61
, Issue.6
, pp. 2641-2648
-
-
Montaner, S.1
Sodhi, A.2
Pece, S.3
Mesri, E.A.4
Gutkind, J.S.5
-
15
-
-
1842687489
-
Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirusencoded G protein-coupled receptor
-
Apr 6 Epub 2004 Mar 26
-
Sodhi A, Montaner S, Patel V, et al. Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirusencoded G protein-coupled receptor. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4821-4826. Epub 2004 Mar 26.
-
(2004)
Proc Natl Acad Sci U S A.
, vol.101
, Issue.14
, pp. 4821-4826
-
-
Sodhi, A.1
Montaner, S.2
Patel, V.3
-
16
-
-
47949101732
-
Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cells
-
Jun 15
-
Wang L, Damania B. Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cells. Cancer Res. 2008 Jun 15;68(12):4640-4648.
-
(2008)
Cancer Res.
, vol.68
, Issue.12
, pp. 4640-4648
-
-
Wang, L.1
Damania, B.2
-
17
-
-
59749095009
-
Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer
-
Apr Epub 2008 Dec 7
-
Chin YR, Toker A. Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer. Cell Signal. 2009 Apr; 21(4):470-476. Epub 2008 Dec 7.
-
(2009)
Cell Signal.
, vol.21
, Issue.4
, pp. 470-476
-
-
Chin, Y.R.1
Toker, A.2
-
18
-
-
1342321750
-
PI 3-kinase, Akt and cell survival
-
Apr
-
Downward J. PI 3-kinase, Akt and cell survival. Semin Cell Dev Biol. 2004 Apr;15(2):177-182.
-
(2004)
Semin Cell Dev Biol.
, vol.15
, Issue.2
, pp. 177-182
-
-
Downward, J.1
-
19
-
-
0029665495
-
Immunohistochemical detection of Bcl-2 in AIDS-associated and classical Kaposi's sarcoma
-
Apr
-
Morris CB, Gendelman R, Marrogi AJ, et al. Immunohistochemical detection of Bcl-2 in AIDS-associated and classical Kaposi's sarcoma. Am J Pathol. 1996 Apr;148(4): 1055-1063.
-
(1996)
Am J Pathol.
, vol.148
, Issue.4
, pp. 1055-1063
-
-
Morris, C.B.1
Gendelman, R.2
Marrogi, A.J.3
-
20
-
-
35348961395
-
Kaposi's sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial cells
-
Sep 14
-
Shelby BD, LaMarca HL, McFerrin HE, et al. Kaposi's sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial cells. Virol J. 2007 Sep 14;4:87.
-
(2007)
Virol J.
, vol.4
, pp. 87
-
-
Shelby, B.D.1
LaMarca, H.L.2
McFerrin, H.E.3
-
21
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
Feb 18
-
Vlahos CJ, Matter WF, Hui KY, Brown RF. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem. 1994 Feb 18; 269(7):5241-5248.
-
(1994)
J Biol Chem.
, vol.269
, Issue.7
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
22
-
-
33746832011
-
The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor
-
Aug
-
Sodhi A, Chaisuparat R, Hu J, et al. The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. Cancer Cell. 2006 Aug;10(2):133-143.
-
(2006)
Cancer Cell.
, vol.10
, Issue.2
, pp. 133-143
-
-
Sodhi, A.1
Chaisuparat, R.2
Hu, J.3
-
23
-
-
0033871130
-
Expression of Bcl-2 in dysplastic and neoplastic cervical lesions in relation to cell proliferation and HPV infection
-
Brychtová S, Brychta T, Kotrsová L, et al. Expression of Bcl-2 in dysplastic and neoplastic cervical lesions in relation to cell proliferation and HPV infection. Neoplasma. 2000;47(3):143-147.
-
(2000)
Neoplasma
, vol.47
, Issue.3
, pp. 143-147
-
-
Brychtová, S.1
Brychta, T.2
Kotrsová, L.3
-
24
-
-
0031787643
-
Expression of Bcl-2 family of proteins in fresh myeloma cells
-
Nov
-
Harada N, Hata H, Yoshida M, et al. Expression of Bcl-2 family of proteins in fresh myeloma cells. Leukemia. 1998 Nov;12(11): 1817-1820.
-
(1998)
Leukemia
, vol.12
, Issue.11
, pp. 1817-1820
-
-
Harada, N.1
Hata, H.2
Yoshida, M.3
-
25
-
-
0029050465
-
High prevalence of bcl-2 oncoprotein expression in small cell lung cancer
-
Mar-Apr
-
Higashiyama M, Doi O, Kodama K, Yokouchi H, Tateishi R. High prevalence of bcl-2 oncoprotein expression in small cell lung cancer. Anticancer Res. 1995 Mar-Apr;15(2):503-505.
-
(1995)
Anticancer Res.
, vol.15
, Issue.2
, pp. 503-505
-
-
Higashiyama, M.1
Doi, O.2
Kodama, K.3
Yokouchi, H.4
Tateishi, R.5
-
26
-
-
0034062695
-
Antiapoptotic bcl-2 and bcl-xL in advanced malignant melanoma
-
May
-
Leiter U, Schmid RM, Kaskel P, Peter RU, Krähn G. Antiapoptotic bcl-2 and bcl-xL in advanced malignant melanoma. Arch Dermatol Res. 2000 May;292(5):225-232.
-
(2000)
Arch Dermatol Res.
, vol.292
, Issue.5
, pp. 225-232
-
-
Leiter, U.1
Schmid, R.M.2
Kaskel, P.3
Peter, R.U.4
Krähn, G.5
-
27
-
-
0021821903
-
Involvement of the bcl-2 gene in human follicular lymphoma
-
Jun 21
-
Tsujimoto Y, Cossman J, Jaffe E, Croce CM. Involvement of the bcl-2 gene in human follicular lymphoma. Science. 1985 Jun 21; 228(4706):1440-1443.
-
(1985)
Science
, vol.228
, Issue.4706
, pp. 1440-1443
-
-
Tsujimoto, Y.1
Cossman, J.2
Jaffe, E.3
Croce, C.M.4
-
28
-
-
54949132875
-
Bcl-2 family proteins and cancer
-
Oct 27
-
Yip KW, Reed JC. Bcl-2 family proteins and cancer. Oncogene. 2008 Oct 27;27(50):6398-6406.
-
(2008)
Oncogene
, vol.27
, Issue.50
, pp. 6398-6406
-
-
Yip, K.W.1
Reed, J.C.2
-
29
-
-
0031669402
-
Bax and Bcl-2 expressions predict response to radiotherapy in human cervical cancer
-
Harima Y, Harima K, Shikata N, Oka A, Ohnishi T, Tanaka Y. Bax and Bcl-2 expressions predict response to radiotherapy in human cervical cancer. J Cancer Res Clin Oncol. 1998;124(9):503-510.
-
(1998)
J Cancer Res Clin Oncol.
, vol.124
, Issue.9
, pp. 503-510
-
-
Harima, Y.1
Harima, K.2
Shikata, N.3
Oka, A.4
Ohnishi, T.5
Tanaka, Y.6
-
30
-
-
0027162207
-
Apoptosis of lung cancer cells caused by some anti-cancer agents (MMC, CPT-11, ADM) is inhibited by bcl-2
-
Apr 15
-
Ohmori T, Podack ER, Nishio K, et al. Apoptosis of lung cancer cells caused by some anti-cancer agents (MMC, CPT-11, ADM) is inhibited by bcl-2. Biochem Biophys Res Commun. 1993 Apr 15;192(1):30-36.
-
(1993)
Biochem Biophys Res Commun.
, vol.192
, Issue.1
, pp. 30-36
-
-
Ohmori, T.1
Podack, E.R.2
Nishio, K.3
-
31
-
-
69049084467
-
LANA-1, Bcl-2, Mcl-1 and HIF-1alpha protein expression in HIV-associated Kaposi sarcoma
-
Aug Epub 2009 May 30
-
Long E, Ilie M, Hofman V, et al. LANA-1, Bcl-2, Mcl-1 and HIF-1alpha protein expression in HIV-associated Kaposi sarcoma. Virchows Arch. 2009 Aug;455(2):159-170. Epub 2009 May 30.
-
(2009)
Virchows Arch.
, vol.455
, Issue.2
, pp. 159-170
-
-
Long, E.1
Ilie, M.2
Hofman, V.3
-
32
-
-
38549145044
-
Diagnosing and exploiting cancer's addiction to blocks in apoptosis
-
Feb
-
Letai AG. Diagnosing and exploiting cancer's addiction to blocks in apoptosis. Nat Rev Cancer. 2008 Feb;8(2):121-132.
-
(2008)
Nat Rev Cancer.
, vol.8
, Issue.2
, pp. 121-132
-
-
Letai, A.G.1
-
33
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Jun 2 Epub 2005 May 15
-
Oltersdorf T, Elmore SW, Shoemaker AR, et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature. 2005 Jun 2;435(7042):677-681. Epub 2005 May 15.
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
-
34
-
-
78649630259
-
Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: A phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity
-
Dec Epub 2010 Nov 18
-
Wilson WH, O'Connor OA, Czuczman MS, et al. Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity. Lancet Oncol. 2010 Dec;11(12):1149-1159. Epub 2010 Nov 18.
-
(2010)
Lancet Oncol.
, vol.11
, Issue.12
, pp. 1149-1159
-
-
Wilson, W.H.1
O'Connor, O.A.2
Czuczman, M.S.3
-
35
-
-
51649105949
-
Expanding circle of inhibition: Smallmolecule inhibitors of Bcl-2 as anticancer cell and antiangiogenic agents
-
Sep 1
-
Zeitlin BD, Zeitlin IJ, Nör JE. Expanding circle of inhibition: smallmolecule inhibitors of Bcl-2 as anticancer cell and antiangiogenic agents. J Clin Oncol. 2008 Sep 1;26(25):4180-4188.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.25
, pp. 4180-4188
-
-
Zeitlin, B.D.1
Zeitlin, I.J.2
Nör, J.E.3
-
36
-
-
77956817252
-
FRP inhibits ox-LDL-induced endothelial cell apoptosis through an Akt-NF-{kappa}B-Bcl-2 pathway and inhibits endothelial cell apoptosis in an apoEknockout mouse model
-
Sep Epub 2010 Jun 8
-
Liu S, Shen H, Xu M, et al. FRP inhibits ox-LDL-induced endothelial cell apoptosis through an Akt-NF-{kappa}B-Bcl-2 pathway and inhibits endothelial cell apoptosis in an apoEknockout mouse model. Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E351-E363. Epub 2010 Jun 8.
-
(2010)
Am J Physiol Endocrinol Metab.
, vol.299
, Issue.3
-
-
Liu, S.1
Shen, H.2
Xu, M.3
-
37
-
-
0034646644
-
Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response elementbinding protein
-
Apr 14
-
Pugazhenthi S, Nesterova A, Sable C, et al. Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response elementbinding protein. J Biol Chem. 2000 Apr 14;275(15):10761-10766.
-
(2000)
J Biol Chem.
, vol.275
, Issue.15
, pp. 10761-10766
-
-
Pugazhenthi, S.1
Nesterova, A.2
Sable, C.3
-
38
-
-
80052061573
-
Upregulation of cellular Bcl-2 by the KSHV encoded RTA promotes virion production
-
Epub 2011 Aug 25
-
Gao J, Cai Q, Lu J, Jha HC, Robertson ES. Upregulation of cellular Bcl-2 by the KSHV encoded RTA promotes virion production. PLoS One. 2011;6(8):e23892. Epub 2011 Aug 25.
-
(2011)
PLoS One.
, vol.6
, Issue.8
-
-
Gao, J.1
Cai, Q.2
Lu, J.3
Jha, H.C.4
Robertson, E.S.5
-
39
-
-
0038540963
-
United at last: The tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling
-
Jun
-
Manning BD, Cantley LC. United at last: the tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling. Biochem Soc Trans. 2003 Jun;31(Pt 3):573-578.
-
(2003)
Biochem Soc Trans.
, vol.31
, Issue.PART 3
, pp. 573-578
-
-
Manning, B.D.1
Cantley, L.C.2
-
40
-
-
18844409151
-
Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax: Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity
-
May 5
-
Tirado OM, Mateo-Lozano S, Notario V. Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax: Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity. Oncogene. 2005 May 5;24(20): 3348-3357.
-
(2005)
Oncogene
, vol.24
, Issue.20
, pp. 3348-3357
-
-
Tirado, O.M.1
Mateo-Lozano, S.2
Notario, V.3
|