An update on pharmaceutical film coating for drug delivery

Expert Opinion on Drug Delivery

Volumn 10, Issue 4, 2013, Pages 421-435

  Felton, Linda A ^a   Porter, Stuart C ^b  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b ASHLAND INC   (United States)

Author keywords

Coating formulation; Continuous coating; Modified drug release; Polymeric film coating, process analytical technologies

Indexed keywords

ACETYLSALICYLIC ACID; ACETYLTRIBUTYL CITRATE; ACETYLTRIETHYL CITRATE; ACRYLIC ACID ETHYL ESTER; CELLACEFATE; CITRIC ACID; CITRIC ACID TRIBUTYL ESTER; CITRIC ACID TRIETHYL ESTER; COPOLYMER; DRUG ADDITIVE; ETHYL CELLULOSE; GLYCEROL STEARATE; GLYCOL; HYDROXYPROPYLMETHYLCELLULOSE; MACROGOL; METHACRYLIC ACID; PHTHALIC ACID DERIVATIVE; PIGMENT; PLASTICIZER; POLYMER; POLYMETHACRYLIC ACID; POLYVINYL ACETATE PHTHALATE; POLYVINYL ALCOHOL; POVIDONE; PROTON PUMP INHIBITOR; SEBACIC ACID; SURFACTANT; TITANIUM DIOXIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINYL ACETATE;

ANALYTIC METHOD; BIOCHEMICAL EQUIPMENT; BIOFILM; CHEMICAL COMPOSITION; CHEMICAL INTERACTION; CHEMICAL PROCEDURES; CONTROLLED DRUG RELEASE; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; REVIEW;

CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EXCIPIENTS; PHARMACEUTICAL PREPARATIONS; POLYMERS; TABLETS, ENTERIC-COATED; TECHNOLOGY, PHARMACEUTICAL;

EID: 84875124544     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2013.763792     Document Type: Review

References (132)

1. Bechard SR, Quraishi O, Kwong E. Film coating: Effect of titanium dioxide concentration and film thickness on the photostability of nifedipine. Int J Pharm 1992;87:133-9
2. Felton LA, Timmins GS. A nondestructive technique to determine the rate of oxygen permeation into solid dosage forms. Pharm Dev Technol 2006;11:1-7
3. Mwesigwa E, Buckton G, Basit AW. The hygroscopicity of moisture barrier film coatings. Drug Dev Ind Pharm 2005;31:959-68
4. Cerea M, Zheng W, Young CR, McGinity JW. A novel powder coating process for attaining taste masking and moisture protective films applied to tablets. InT J Pharm 2004;279:127-39
5. Dashevsky A, Mohamad A. Development of pulsatile multiparticulate drug delivery system coated with aqueous dispersion Aquacoat(R) ECD. InT J Pharm 2006;318:124-31
6. Dashevsky A, Wagner K, Kolter K, Bodmeier R. Physicochemical and release properties of pellets coated with Kollicoat SR 30 D, a new aqueous polyvinyl acetate dispersion for extended release. Int J Pharm 2005;290:15-23
7. Siepmann F, Wahle C, Leclercq B, et al. pH-sensitive film coatings. Towards a better understanding and facilitated optimization. eur j pharm biopharm 2008;68:2-10
8. Felton LA, Haase MM, Shah NH, et al. Physical and enteric properties of soft gelatin capsules coated with Eudragit L 30 D-55. InT J Pharm 1995;113:17-24
9. Liu Y, Sun YH, Sun J, et al. Preparation and in vitro/in vivo evaluation of sustained-release venlafaxine hydrochloride pellets. InT J Pharm 2012;426:21-8
10. Farag Y, Leopold CS. Development of shellac-coated sustained release pellet formulations. eur J pharm biopharm 2011;42:400-5
11. Reix N, Guhmann P, Bietiger W, et al. Duodenum-specific drug delivery. In vivo assessment of a pharmaceutically developed enteric-coated capsule for a broad applicability in rat studies. Int J Pharm 2012;422:338-40
12. Carlin B, Li J-X, Felton LA. Pseudolatex dispersions for controlled drug delivery. In: McGinity JW, Felton LA, editors. Aqueous polymeric coatings for pharmaceutical dosage forms. Informa Healthcare, New York; 2008
13. Kiil S. Drying of latex films and coatings: Reconsidering the fundamental mechanisms. Progr Org Coat 2006;57(3):236-50
14. Felton LA. Mechanisms of polymeric film formation. Int J Pharm 2013; In press
15. Muschert S, Siepmann F, Leclercq B, Siepmann J. Dynamic and static curing of ethylcellulose:PVA-PEG graft copolymer film coatings. Eur J Pharm Biopharm 2011;78:455-61
16. Farag Y, Leopold CS. Influence of the inlet air temperature in a fluid bed coating process on drug release from shellac-coated pellets. Drug Dev Ind Pharm 2011;37:319-27
17. Yang QW, Flament MP, Siepmann F, et al. Curing of aqueous polymeric film coatings: Importance of the coating level and type of plasticizer. Eur J Pharm Biopharm 2010;74:362-70
18. Bodmeier R, Paeratakul O. The effect of curing on drug release and morpholoigal properties of ethylcellulose pseudolatex-coated beads. Drug Dev Ind Pharm 1994;20(9):1517-33
19. Tabasi SH, Fahmy R, Bensley D, et al. Quality by design, part III: Study of curing process of sustained release coated products using NIR spectroscopy. J Pharm Sci 2008;97:4067-86
20. Zheng W, McGinity JW. Influence of Eudragit NE 30 D blended with Eudragit L 30 D-55 on the release of phenylpropanolamine hydrochloride from coated pellets. Drug Dev Ind Pharm 2003;29(3):357-66
21. Williams RO III, Liu J. The influence of plasticizer on heat-humidity curing of cellulose acetate phthalate coated beads. Pharm Dev Technol 2001;6(4):607-19
22. Williams RO III, Liu J. Influence of processing and curing conditions on beads coated with an aqueous dispersion of cellulose acetate phthalate. Eur J Pharm Biopharm 2000;49:243-52
23. Wesseling M, Bodmeier R. Influence of plasticization time, curing conditions, storage time, and core properties on the drug release from aquacoat-coated pellets. Pharm Dev Technol 2001;6(3):325-31
24. Bhattacharjya S, Wurster DE. Investigation of the drug release and surface morphological properties of film-coated pellets, and physical, thermal and mechanical properties of free films as a function of various curing conditions. AAPS PharmSciTech 2008;9:449-57
25. Fadda HM, Mohamed MA, Basit AW. Impairment of the in vitro drug release behaviour of oral modified release preparations in the presence of alcohol. Int J Pharm 2008;360:171-6
26. Freire C, Podczeck F, Veiga F, Sousa J. Influence of the coating formulation on enzymatic digestibility and drug release from 5-aminosalicylic acid pellets coated with mixtures of high-amylose starch and Surelease(R) intended for colon-specific drug delivery. Drug Dev Ind Pharm 2010;36:161-72
27. Ensslin S, Moll KP, Metz H, et al. Modulating pH-independent release from coated pellets: Effect of coating composition on solubilization processes and drug release. Eur J Pharm Biopharm 2009;72:111-18
28. Rohera BD, Parikh NH. Influence of plasticizer type and coat level on Surelease film properties. Pharm Dev Technol 2002;7(4):407-20
29. Sadeghi F, Ford JL, Rajabi-Siahboomi A. The influence of drug type on the release profiles from Surelease-coated pellets. Int J Pharm 2003;254:123-35
30. Struebing S, Metz H, Maeder K. Mechanistic analysis of drug release from tablets with membrane controlled drug delivery. Eur J Pharm Biopharm 2007;66:113-19
31. Sadeghi F, Ford JL, Rubinstein MH, Rajabi-Siahboomi AR. Study of drug release from pellets coated with surelease containing hydroxypropyl methylcellulose. Drug Dev Ind Pharm 2001;27(5):419-30
32. Verma RK, Mishra B, Garg S. Osmotically controlled oral drug delivery. Drug Dev Ind Pharm 2000;26:695-708
33. Binschaedler C, Gurny R, Doelker E. Osmotic water transport through cellulose acetate membranes produced from a latex system. J Pharm Sci 1987;76(6):455-60
34. Sastry SV, Khan MA. Aqueous based polymeric dispersion: Plackett-Burman design for screening of formulation variables of atenolol gastrointestinal therapeutic system. Pharm Acta Helv 1998;73:105-12
35. Ramakrishna N, Mishra B. Plasticizer effect and comparative evaluation of cellulose acetate and ethylcellulose-HPMC combination coatings as semipermeable membranes for oral osmotic pumps of naproxen sodium. Drug Dev Ind Pharm 2002;28(4):403-12
36. Verma RK, Kaushal AM, Garg S. Development and evaluation of extended release formulations of isosorbide mononitrate based on osmotic technology. Int J Pharm 2003;263:9-24
37. Thombre AG, Cardinal JR, DeNoto AR, et al. Asymmetric membrane capsules for osmotic drug delivery I. Development of a manufacturing process. J Control Rel 1999;57(1):55-64
38. Patel V, Chudasama A, Nivsarkar M, et al. Push-pull osmotic pump for zero order delivery of lithium carbonate: Development and in vitro characterization. 2012;17:375-82
39. Cole ET, Scott RA, Connor AL, et al. Enteric coated HPMC capsules designed to achieve intestinal targeting. Int J Pharm 2002;231:83-95
40. Thoma K, Bechtold K. Influence of aqueous coatings on the stability of enteric coated pellets and tablets. Eur J Pharm Biopharm 1999;47(1):39-50
41. Lecomte F, Siepmann J, Walther M, et al. pH-sensitive polymer blends used as coating materials to control drug release from spherical beads: Elucidation of the underlying mass transport mechanisms. Pharm Res 2005;22(7):1129-41
42. Karrout Y, Neut C, Wils D, et al. Characterization of ethylcellulose: Starch-based film coatings for colon targeting. Drug Dev Ind Pharm 2009;35:1190-200
43. Koerber M, Ciper M, Hoffart V, et al. Enteric polymers as acidifiers for the pH-independent sustained delivery of a weakly basic drug salt from coated pellets. Eur J Pharm Biopharm 2011;78:447-54
44. Gupta VK, Beckert T, Deusch N, et al. Investigation of potential ionic interactions between anionic and cationic polymethacrylates of multiple coatings of novel colonic delivery system. Drug Dev Ind Pharm 2002;28(2):207-15
45. Amighi K, Moes A. Influence of plasticizer concentration and storage conditions on the drug release rate from Eudragit RD30D film-coated sustainedrelease Theophylline pellets. Eur J Pharm Biopharm 1996;42(1):29-35
46. Bodmeier R, Paeratakul O. Process and formulation variables affecting the drug release from chlorpheniramine maleate-loaded beads coated with commercial and self-prepared aqueous ethyl cellulose pseudolatexes. Int J Pharm 1991;70:59-68
47. Wu T, Pan W, Chen J, Zhang R. Studies of the drug permeability and mechanical properties of free films prepared by cellulose acetate pseudolatex coating system. Drug Dev Ind Pharm 2000;26(1):95-102
48. Felton LA, Shah NH, Zhang G, et al. Compaction properties of individual non-pareil beads coated with an acrylic resin copolymer. STP Pharm Sci 1997;7(6):457-62
49. Felton LA, McGinity JW. Influence of plasticizers on the adhesive properties of an acrylic resin copolymer to hydrophilic and hydrophobic tablet compacts. Int J Pharm 1997;154:167-78
50. Rowe RC. Adhesion of film coatings to tablet surfaces-a theoretical approach based on solubility parameters. Int J Pharm 1988;41:219-22
51. Felton LA, Shah NH, Zhang G, et al. Physical-mechanical properties of film-coated soft gelatin capsules. Int J Pharm 1996;127:203-11
52. Bodmeier R, Paeratakulb O. Plasticizer uptake by aqueous colloidal polymer dispersions used for the coating of solid dosage forms. Int J Pharm 1997;152(1):17-26
53. Gutierrez-Rocca JC, McGinity JW. Influence of water soluble and insoluble plasticizers on the physical and mechanical properties of acrylic resin copolymers. Int J Pharm 1994;103:293-301
54. Bodmeier R, Paeratakul O. The distribution of plasticizers between aqueous and polymer phases in aqueous colloidal polymer dispersions. Int J Pharm 1994;103:47-54
55. Siepmann J, Paeratakul O, Bodmeier R. Modeling plasticizer uptake in aqueous polymer dispersions. Int J Pharm 1998;165:191-200
56. Porter SC, Felton LA. Techniques to assess film coatings and evaluate film-coated products. Drug Dev Ind Pharm 2010;36(2):128-42
57. Felton LA. Characterization of coating systems. AAPS Pharm Sci Tech 2007;8(4):112
58. Felton LA, O'Donnell PB, McGinity JW. Mechanical properties of polymeric films prepared from aqueous dispersions. In: McGinity JW, Felton LA, editors. Aqueous polymeric coatings for pharmaceutical dosage forms. Informa Healthcare; New York City: 2008
59. Felton LA. Coating systems for oral controlled release formulations. In: Wen H, Park K, editors. Oral controlled release formulation design and drug delivery. John Wiley & Sons, Inc; Hoboken, NJ: 2010
60. Fassihi RA, McPhillips AM, Uraizee SA, Sakr AM. Potential use of magnesium stearate and talc as dissolution retardants in the development of controlled drug delivery systems. Pharm Ind 1994;56(6):579-83
61. Maejima T, McGinity JW. Influence of film additives on stabilizing drug release rates from pellets coated with acrylic polymers. Pharm Dev Technol 2001;6(2):211-21
62. Okhamafe AO, York P. Relationship between stress, interaction and the mechanical properties of some pigmented tablet coating films. Drug Dev Ind Pharm 1985;11(1):131-46
63. Gibson SHM, Rowe RC, White ET. Mechanical properites of pigmented tablet coating formulations and their resistance to cracking. I. Static mechanical measurement. Int J Pharm 1988;48:63-77
64. Okhamafe AO, York P. Effect of solids-polymer interactions on the properties of some aqueous-based tablet film coating formulations. II. Mechanical characteristics. Int J Pharm 1984;22:273-81
65. Nimkulrat S, Suchiva K, Phinyocheep P, Puttipipathachorn S. Influence of selected surfactants on the tackiness of acrylic polymer films. Int J Pharm 2004;287:27-37
66. Rowe RC, Sheskey PJ, Owen S. Handbook of pharmaceutical excipients. Pharmaceutical Press; London: 2006
67. Felton LA, McGinity JW. Influence of insoluble excipients on film coating systems. Drug Dev Ind Pharm 2002;28(3):225-43
68. Felton LA, McGinity JW. Influence of pigment concentration and particle size on adhesion of an acrylic resin copolymer to tablet compacts. Drug Dev Ind Pharm 1999;25(5):599-606
69. Maul KA, Schmidt PC. Influence of different-shaped pigments on bisacodyl release from Eudragit L 30 D. InT J Pharm 1995;118:103-12
70. Maul KA, Schmidt PC. Influence of different-shaped pigments and plasticizers on theophylline release from Eudragit RS30D and Aquacoat ECD30 coated pellets. STP Pharm Sci 1997;7(6):498-506
71. Nyamweya N, Mehta KA, Hoag SW. Characterization of the interactions between polymethacrylate-based aqueous polymeric dispersions and aluminum lakes. J Pharm Sci 2001;90:1-11
72. Rowe RC. Modulus enhancement in pigmented tablet film coating formulations. Int J Pharm 1983;14:355-9
73. Felton LA, Austin-Forbes T, Moore TA. Influence of surfactants in aqueous-based polymeric dispersions on the thermo-mechanical and adhesive properties of acrylic films. Drug Dev Ind Pharm 2000;26(2):205-10
74. Lindholm T, Juslin M, Lindholm B-A, et al. Properties of free ethyl cellulose films containing surfactant and particulate matter. Pharm Ind 1987;49(7):740-6
75. Lindholm T, Lindholm B-A, Niskanen M, Koskiniemi J. Polysorbate 20 as a drug release regulator in ethyl cellulose film coatings. J Pharm Pharmacol 1986;38:686-8
76. Heinicke G, Schwartz JB. The influence of Surfactants and additives on drug release from a cationic Eudragit coated multiparticulate diltiazem formulation. Pharm Dev Technol 2007;12:381-9
77. Mehta AM. Processing and equipment considerations for aqueous coatings. In: McGinity JW, Felton LA, editors. Aqueous polymeric coatings for pharmaceutical dosage forms. Informa Healthcare, New York City; 2008
78. Barbash D, Fulghum JE, Yang J, Felton LA. A novel imaging technique to investigate the influence of atomization air pressure on film-tablet interfacial thickness. Drug Dev Ind Pharm 2009;35(4):480-6
79. Tobiska S, Kleinebudde P. Coating uniformity: Influence of atomizing air pressure. Pharm Dev Technol 2003;8(1):39-46
80. Felton LA, Perry WL. A novel technique to quantify film-tablet interfacial thickness. Pharm Dev Technol 2002;7(1):1-5
81. Bodmeier R, Paeratakul O. Evaluation of drug-containing polymer films prepared from aqueous latexes. Pharm Res 1989;6(8):725-30
82. Bruce LD, Petereit HU, Beckert T, McGinity JW. Properties of enteric coated sodium valproate pellets. Int J Pharm 2003;264:85-96
83. Bruce LD, Koleng JJ, McGinity JW. The influence of polymeric subcoats and pellet formulation on the release of chlorpheniramine maleate from enteric coated pellets. Drug Dev Ind Pharm 2003;29(8):909-24
84. Cunningham C, Kinsey BR, Scattergood LK, Turnbull N. The effect of tablet shape on the application of an enteric film coating. American Association of Pharmaceutical Scientists; Toronto, Canada: 2002
85. Felton LA, McGinity JW. Adhesion of polymeric films to pharmaceutical solids. Eur J Pharm Biopharm 1999;47(1):1-14
86. Bodmeier R. Tableting of coated pellets. Eur J Pharm Biopharm 1997;43:1-8
87. Dashevsky A, Kolter K, Bodmeier R. Compression of pellets coated with various aqueous polymer dispersions. Int J Pharm 2004;279:19-26
88. Sarisuta N, Punpreuk K. In vitro properties of film-coated diltiazem hydrochloride pellets compressed into tablets. J Control Release 1994;31:215-22
89. Lopez-Rodriguez FJ, Torrado JJ, Torrado S, et al. Compression behavior of acetylsalicyclic acid pellets. Drug Dev Ind Pharm 1993;19(12):1369-77
90. Felton LA, Friar AL. Enteric coating of gelatin and cellulosic capsules using an aqueous-based acrylic polymer. American Association of Pharmaceutical Scientists; Toronto, Canada: 2002
91. Felton LA, McGinity JW. Adhesion of polymeric films. In: McGinity JW, Felton LA, editors. Aqueous polymeric coatings for pharmaceutical dosage forms. Informa Healthcare, New york City; 2008
92. Rowe RC. The measurement of the adhesion of film coatings to tablet surfaces: The effect of tablet porosity, surface roughness, and film thickness. J Pharm Pharmacol 1978;30:343-6
93. Felton LA, McGinity JW. Influence of tablet hardness and hydrophobicity on the adhesive properties of an acrylic resin copolymer. Pharm Dev Technol 1996;1(4):381-9
94. Johnson BA, Zografi G. Adhesion of hydroxypropyl cellulose films to low energy solid substrates. J Pharm Sci 1986;75(6):529-33
95. Rowe RC. The adhesion of film coatings to tablet surfaces-measurement on biconvex tablets. J Pharm Pharmacol 1977;29:58-9
96. Rowe RC. A reappraisal of the equations used to predict the internal stresses in film coatings applied to tablet substrates. J Pharm Pharmacol 1983;35:112-13
97. Croll SG. The origin of residual internal stress in solvent-cast thermoplastic coatings. J Appl Polym Sci 1979;23:847-58
98. Sato K. The internal stress of coating films. Prog Org Coating 1980;8:143-60
99. Okutgen E, Hogan JE, Aulton ME. Effects of tablet core dimensional instability on the generation of internal stresses within film coats. Part 1. Influence of temperature changes during the film coating process. Drug Dev Ind Pharm 1991;17(9):1177-89
100. Lehtola V-M, Heinamaki JT, Nikupaavo P, Yliruusi JK. Effect of some excipients and compression pressure on the adhesion of aqueous-based hydroxypropyl methylcellulose film coatings to tablet surface. Drug Dev Ind Pharm 1995;21(12):1365-75
101. Khan H, Fell JT, Macleod GS. The influence of additives on the spreading coefficient and adhesion of a film coating formulation to a model tablet surface. InT J Pharm 2001;227:113-19
102. Felton LA, Baca ML. Influence of curing on the adhesive and mechanical properties of an applied acrylic polymer. Pharm Dev Technol 2001;6(1):1-9
103. Page S, Baumann KH, Kleinebudde P. Mathematical modeling of an aqueous film coating process in a Bohle Lab-Coater: Part 2: Application of the model. AAPS PharmSciTech 2006;7(2):E87-94
104. Pandey P, Katakdaunde M, Turton R. Modeling weight variability in a pan coating process using Monte Carlo simulations. AAPS PharmSciTech 2006;7(4):E2-E11
105. Pandey P, Turton R. Movement of different shaped particles in a pan-coating device using novel video-imaging techniques. AAPS PharmSci 2005;6(2):E237-44; Article 34
106. Ketterhagen WR. Modeling the motion and orientation of various pharmaceutical tablet shapes in a film coating pan using DEM. Int J Pharm 2011;409:137-49
107. Romer M, Heinamaki J, Strachan C, et al. Prediction of tablet film-coating thickness using a rotating plate coating system and NIR spectroscopy. AAPS PharmSciTech 2008;9(4):1047-53
108. Choi M. Applications of process thermodynamics in pharmaceutical coating. Tablets Capsules 2007;4:1-10
109. Kalbag A, Wassgren C, Penumetcha SS, Perez-Ramos J. Inter-tablet coating variability: Residence times in a horizontal pan coater. Chem Eng Sci 2008;63:2881-94
110. Perez-Ramos J, Wassgren C, Hoon V, Morris KR. Modeling and monitoring of tablet bed dynamics in a side-vented pan coater by digital video analysis. American Association of Pharmaceutical Scientists, Nashville, TN (Conference presentation); 2005
111. Chen W, Chang S-Y, Kiang S, et al. Modeling of pan coating processes: Prediction of tablet content uniformity and determination of critical process parameters. J Pharm Sci 2010;99(7):3213-25
112. Turton R. Challenges in the modeling and prediction of coating of pharmaceutical dosage forms. Powd Tech 2008;181:186-94
113. Lee MJ, Seo DY, Lee HE, et al. In line NIR quantification of film thickness on pharmaceutical pellets during a fluid bed coating process. Int J Pharm 2011;403:66-72
114. May RK, Evans MJ, Zhong S, et al. Terahertz in-line sensor for direct coating thickness measurement of individual tablets during film coating in real-time. J Pharm Sci 2011;100(4):1535-44
115. Muller J, Knop K, Thies J, et al. Feasibility of raman spectroscopy as PAT tool in active coating. Drug Dev Ind Pharm 2010;36(2):234-43
116. Wang J, Hemenway J, Chen W, et al. An evaluation of process parameters to improve coating efficiency of an active tablet film-coating process. Int J Pharm 2012;427:163-9
117. Porter SC. Scale-up of film coating. In: Levin M, editor. Pharmaceutical process scale-up. Informa Healthcare, New York 2011; p. 444-489
118. Siepmann F, Le Brun V, Siepmann J. Drugs acting as plasticizers in polymeric systems: A quantitative treatment. J Control Release 2006;115:298-306
119. Wu C, McGinity JW. Non-traditional plasticization of polymeric films. Int J Pharm 1999;177:15-27
120. Porter SC, Terzian L, Hadfield PJ, et al. Examination of the benefits of the use of high-solids film coating systems as a means of reducing the costs of aqueous coating processes. American Association of Pharmaceutical Scientists, Washington, DC; 2011
121. Terzian L, Menchon M, Porter SC. The application of an aqueous high-solids coating system at low bed temperatures. American Association of Pharmaceutical Scientists; Washington, DC: 2011
122. Mancoff WO. Film coating compressed tablets in a continuous process. Pharm Tech 1998;22(Suppl):12-18
123. Porter SC. Continuous film coating processes: A review. Tablets Capsules 2007;4:26-9
124. Marjeram J. Advantages of continuous pharmaceutical tablet coating. Tablets Capsules 2011;4:14-17
125. Cahyadi C, Heng PW, Chan LW. Optimization of process parameters for a quasi-continuous tablet coating system using design of experiments. AAPS Pharm Sci Tech 2011;12:119-31
126. Houlton S. Electrostatics in continuous tablet coating. Manuf Chem 1998;69:13; 16
127. Qiao MX, Luo YF, Zhang LQ, et al. Sustained release coating of tablets with Eudragit(R) RS/RL using a novel electrostatic dry powder coating process. Int J Pharm 2010;399:37-43
128. Porter SC. Coating of pharmaceutical dosage forms. In: DeraMarderosian A, Hanson GR, Medwick T, Popovich NG, Schnaare RL, Schwartz JB, White HS, editors. Remington: The science and practice of pharmacy. Lippincott Williams and Wilkins, Philadelphia; 2006
129. Pearnchob N, Bodmeier R. Dry polymer powder coating and comparison with conventional liquid-based coatings for Eudragit RS, ethyl cellulose, and shellac. Eur J Pharm Biopharm 2003;56:363-9
130. Bodmeier R, McGinity JW. Powder-coating systems. Drug Del Technol 2005;5(9):70-3
131. Obara S, Maruyama N, Nishiyama Y, Kokubo H. Dry coating: An innovative enteric coating method using a cellulose derivative. Eur J Pharm Biopharm 1999;47:51-9
132. Sauer D, Zheng W, Coots LB, Mcginity JW. Influence of processing parameters and formulation factors on the drug release from tablets powder-coated with eudragit/l 100-55. Eur J Pharm Biopharm 2007;67:464-75