Sustained release coating of tablets with Eudragit® RS/RL using a novel electrostatic dry powder coating process

International Journal of Pharmaceutics

Volumn 399, Issue 1-2, 2010, Pages 37-43

  Qiao, Mingxi ^a,b   Luo, Yanfeng ^a   Zhang, Liqiang ^a   Ma, Yingliang ^a   Stephenson, Tyler Shawn ^a   Zhu, Jesse ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Electrostatic dry powder coating; Eudragit RL; Eudragit RS; Sustained release

Indexed keywords

EUDRAGIT; PLASTICIZER; POLYMER;

AEROSOL; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG COATING; DRY POWDER; ELECTRIC CONDUCTIVITY; GLASS TRANSITION TEMPERATURE; IN VITRO STUDY; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; STATIC ELECTRICITY; SUSTAINED DRUG RELEASE; TABLET;

ACRYLIC RESINS; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG COMPOUNDING; HOT TEMPERATURE; IBUPROFEN; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; PHASE TRANSITION; POLYMERS; POWDERS; SOLUBILITY; STATIC ELECTRICITY; SURFACE PROPERTIES; TABLETS, ENTERIC-COATED;

EID: 77956870894     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.07.047     Document Type: Article

References (22)

1. Amighi K., Moes A. Influence of plasticizer concentration and storage condition on the drug release rate from Eudragit RS30D film-coated sustained release theophylline pellets. Eur. J. Pharm. Biopharm. 1996, 42:29-35.
2. Bose S., Bogner R.H. Solventless pharmaceutical coating processes: a review. Pharm. Dev. Technol. 2007, 12:115-131.
3. Cerea M., Zheng W., Young C.R., McGinity J.W. A novel powder coating process for attaining taste masking and moisture protective films applied to tablets. Int. J. Pharm. 2004, 279:127-139.
4. Pharmaceutical Coating Technology 1995, 1-5. Taylor and Francis, London. G. Cole, J. Hogan, M. Aulton (Eds.).
5. Feather, D.H., Nelson, D.H., 2002. Electrostatic application of powder material to solid dosage forms in an electric field. WO Patent Publication 049771, 27 June.
6. Grosvenor M.P., Staniforth J.N. The influence of water on electrostatic charge retention and dissipation in pharmaceutical compacts for powder coating. Pharm. Res. 1996, 13:1725-1729.
7. Hallett, M.D., 2006. Method and apparatus for applying powder in a pattern to a substrate. US Patent Publication 20,060,099,350.
8. Kablitz C.D., Kapplb M., Urbanetza N.A. Parameters influencing polymer particle layering of the dry coating process. Eur. J. Pharm. Biopharm. 2008, 69:760-768.
9. Kablitz C.D., Urbanetz N.A. Characterization of the film formation of the dry coating process. Eur. J. Pharm. Biopharm. 2007, 67:449-457.
10. Klar F., Urbanetz N.A. The role of capillary force promoters in dry coating procedures - evaluation of acetylated monoglyceride, isopropyl myristate and palmitate. Eur. J. Pharm. Biopharm. 2009, 71:124-129.
11. Lecomte F., Siepmann J., Walther M., MacRae R.J., Bodmeier R. Blends of enteric and GIT-insoluble polymers used for film coating: physicochemical characterization and drug release patterns. J. Control. Release 2003, 89:457-471.
12. Lehman K. Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms 1997, 101-176. Marcel Dekker, New York. 2nd ed. J.W. McGinity (Ed.).
13. Obara S., Maruyama N., Nishiyama Y., Kokubo H. Dry coating: an innovative enteric coating method using a cellulose derivative. Eur. J. Pharm. Biopharm. 1999, 47:51-59.
14. Pearnchob N., Bodmeier R. Dry powder coating of pellets with micronized Eudragit RS for extended drug release. Pharm. Res. 2003, 20:1970-1976.
15. Pearnchob N., Bodmeier R. Dry polymer powder coating and comparison with conventional liquid-based coatings for Eudragit RS, ethylcellulose and shellac. Eur. J. Pharm. Biopharm. 2003, 56:363-369.
16. Pearnchob N., Bodmeier R. Coating of pellets with micronized ethylcellulose particles by a dry powder coating technique. Int. J. Pham. 2003, 268:1-11.
17. Plazier-Vercammen J.A., De Neve R.E. Evaluation of water and organic coating formulations for the protection of tablets against humidity. Pharmazie 1993, 48:441-446.
18. Sauer D., Zheng W., Coots L.B., McGinity J.W. Influence of processing parameters and formulation factors on the drug release from tablets powder-coated with Eudragit L 100-55. Eur. J. Pharm. Biopharm. 2007, 67:464-475.
19. Schultz P., Kleinebudde P. A new multiparticulate delayed release system. Part I: dissolution properties and release mechanism. J. Control. Release 1997, 47:181-189.
20. Whiteman, M., Hallett, M.D., Feather, D.H., Nelson, D.H., Gazza, J.M., 2003. Electrostatic application of powder material to solid dosage forms. WO Patent Publication 061841, 31 July.
21. Zheng W., Cerea M., Sauer D., Mcginity J.W. Properties of theophylline tablets powder-coated with methacrylate ester copolymers. J. Drug Deliv. Sci. 2004, 14:319-325.
22. Zhu, J., Luo, Y., Ma, Y., Zhang, H., 2007. Direct coating solid dosage forms using powdered materials. US Patent Publication 2007-0128274, June 7.