Quantifying the contribution of the liver to glucose homeostasis: A detailed kinetic model of human hepatic glucose metabolism

PLoS Computational Biology

Volumn 8, Issue 6, 2012, Pages

  König, Matthias ^a   Bulik, Sascha ^a   Holzhütter, Hermann Georg ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIGITAL STORAGE; INSULIN; KINETIC PARAMETERS; KINETIC THEORY; METABOLISM; PATHOLOGY; PHYSIOLOGICAL MODELS; PHYSIOLOGY;

DETAILED KINETIC MODELLING; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE PRODUCTION; GLYCOGEN METABOLISM; HORMONAL CONTROL; HUMAN HEPATOCYTES; HYPERGLYCAEMIA; HYPOGLYCAEMIA;

GLUCOSE;

ADRENALIN; GLUCAGON; GLUCOSE; INSULIN;

ARTICLE; ENZYME PHOSPHORYLATION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE UTILIZATION; GLYCOGEN ANALYSIS; GLYCOGEN LIVER LEVEL; GLYCOGEN STORAGE DISEASE; GLYCOGEN SYNTHESIS; GLYCOGENOLYSIS; GLYCOLYSIS; HORMONAL REGULATION; HORMONE METABOLISM; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPOGLYCEMIA; LIMIT OF QUANTITATION; LIVER METABOLISM; MATHEMATICAL ANALYSIS; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR MODEL; POSTPRANDIAL STATE; QUANTITATIVE ANALYSIS; SIMULATION; VALIDATION PROCESS;

EID: 84875076718     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002577     Document Type: Article

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