-
1
-
-
0014951784
-
Abnormal alpha-cell function in diabetes. Response to carbohydrate and protein ingestion
-
Muller WA, Faloona GR, Aguilar-Parada E, Unger RH (1970) Abnormal alpha-cell function in diabetes. Response to carbohydrate and protein ingestion. N Engl J Med 283:109-115
-
(1970)
N Engl J Med
, vol.283
, pp. 109-115
-
-
Muller, W.A.1
Faloona, G.R.2
Aguilar-Parada, E.3
Unger, R.H.4
-
2
-
-
0023109225
-
Documentation of hyperglucagonemia throughout the day in nonobese and obese patients with noninsulin-dependent diabetes mellitus
-
Reaven GM, Chen YD, Golay A, Swislocki AL, Jaspan JB (1987) Documentation of hyperglucagonemia throughout the day in nonobese and obese patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 64:106-110
-
(1987)
J Clin Endocrinol Metab
, vol.64
, pp. 106-110
-
-
Reaven, G.M.1
Chen, Y.D.2
Golay, A.3
Swislocki, A.L.4
Jaspan, J.B.5
-
3
-
-
0019861204
-
Glucagon and the A cell: Physiology and pathophysiology (first of two parts)
-
Unger RH, Orci L (1981) Glucagon and the A cell: physiology and pathophysiology (first of two parts). N Engl J Med 304:1518-1524
-
(1981)
N Engl J Med
, vol.304
, pp. 1518-1524
-
-
Unger, R.H.1
Orci, L.2
-
4
-
-
0019498093
-
Glucagon and the A cell: Physiology and pathophysiology (second of two parts)
-
Unger RH, Orci L (1981) Glucagon and the A cell: physiology and pathophysiology (second of two parts). N Engl J Med 304:1575-1580
-
(1981)
N Engl J Med
, vol.304
, pp. 1575-1580
-
-
Unger, R.H.1
Orci, L.2
-
5
-
-
0023589251
-
Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type-II diabetics
-
Baron AD, Schaeffer L, Shragg P, Kolterman OG (1987) Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type-II diabetics. Diabetes 36:274-283
-
(1987)
Diabetes
, vol.36
, pp. 274-283
-
-
Baron, A.D.1
Schaeffer, L.2
Shragg, P.3
Kolterman, O.G.4
-
6
-
-
0028883204
-
Failure of glucagon suppression contributes to postprandial hyperglycaemia in IDDM
-
Dinneen S, Alzaid A, Turk D, Rizza R (1995) Failure of glucagon suppression contributes to postprandial hyperglycaemia in IDDM. Diabetologia 38:337-343
-
(1995)
Diabetologia
, vol.38
, pp. 337-343
-
-
Dinneen, S.1
Alzaid, A.2
Turk, D.3
Rizza, R.4
-
7
-
-
0025066579
-
Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM
-
Mitrakou A, Kelley D, Veneman T et al (1990) Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM. Diabetes 39:1381-1390
-
(1990)
Diabetes
, vol.39
, pp. 1381-1390
-
-
Mitrakou, A.1
Kelley, D.2
Veneman, T.3
-
8
-
-
0034524938
-
Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus
-
Shah P, Vella A, Basu A, Basu R, Schwenk WF, Rizza RA (2000) Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab 85:4053-4059
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 4053-4059
-
-
Shah, P.1
Vella, A.2
Basu, A.3
Basu, R.4
Schwenk, W.F.5
Rizza, R.A.6
-
9
-
-
0034037931
-
Impaired glucose tolerance: The irrepressible alpha-cell?
-
Ipp E (2000) Impaired glucose tolerance: the irrepressible alpha-cell? Diabetes Care 23:569-570
-
(2000)
Diabetes Care
, vol.23
, pp. 569-570
-
-
Ipp, E.1
-
10
-
-
12244268666
-
On the physiology of GIP and GLP-1
-
Holst JJ (2004) On the physiology of GIP and GLP-1. Horm Metab Res 36:747-754
-
(2004)
Horm Metab Res
, vol.36
, pp. 747-754
-
-
Holst, J.J.1
-
11
-
-
0027248866
-
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
-
Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W (1993) Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 36:741-744
-
(1993)
Diabetologia
, vol.36
, pp. 741-744
-
-
Nauck, M.A.1
Kleine, N.2
Orskov, C.3
Holst, J.J.4
Willms, B.5
Creutzfeldt, W.6
-
12
-
-
0038574573
-
Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia
-
Meier JJ, Gallwitz B, Siepmann N et al (2003) Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia. Diabetologia 46:798-801
-
(2003)
Diabetologia
, vol.46
, pp. 798-801
-
-
Meier, J.J.1
Gallwitz, B.2
Siepmann, N.3
-
13
-
-
0022617246
-
Reduced incretin effect in type 2 (non-insulin-dependent) diabetes
-
Nauck M, Stockmann F, Ebert R, Creutzfeldt W (1986) Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia 29:46-52
-
(1986)
Diabetologia
, vol.29
, pp. 46-52
-
-
Nauck, M.1
Stockmann, F.2
Ebert, R.3
Creutzfeldt, W.4
-
14
-
-
0034880655
-
Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients
-
Toft-Nielsen MB, Damholt MB, Madsbad S et al (2001) Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients. J Clin Endocrinol Metab 86:3717-3723
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 3717-3723
-
-
Toft-Nielsen, M.B.1
Damholt, M.B.2
Madsbad, S.3
-
15
-
-
0001095690
-
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients
-
Vilsboll T, Krarup T, Deacon CF, Madsbad S, Holst JJ (2001) Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients. Diabetes 50:609-613
-
(2001)
Diabetes
, vol.50
, pp. 609-613
-
-
Vilsboll, T.1
Krarup, T.2
Deacon, C.F.3
Madsbad, S.4
Holst, J.J.5
-
16
-
-
0037312821
-
The influence of GLP-1 on glucose-stimulated insulin secretion - effects on beta-cell sensitivity in type 2 and nondiabetic subjects
-
Kjems LL, Holst JJ, Volund A, Madsbad S (2003) The influence of GLP-1 on glucose-stimulated insulin secretion - effects on beta-cell sensitivity in type 2 and nondiabetic subjects. Diabetes 52:380-386
-
(2003)
Diabetes
, vol.52
, pp. 380-386
-
-
Kjems, L.L.1
Holst, J.J.2
Volund, A.3
Madsbad, S.4
-
17
-
-
0036373430
-
Defective amplification of the late phase insulin response to glucose by GIP in obese type II diabetic patients
-
Vilsboll T, Krarup T, Madsbad S, Holst JJ (2002) Defective amplification of the late phase insulin response to glucose by GIP in obese type II diabetic patients. Diabetologia 45:1111-1119
-
(2002)
Diabetologia
, vol.45
, pp. 1111-1119
-
-
Vilsboll, T.1
Krarup, T.2
Madsbad, S.3
Holst, J.J.4
-
18
-
-
2342502454
-
Report of the expert committee on the diagnosis and classification of diabetes mellitus
-
No authors listed
-
No authors listed (2002) Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 25 (Suppl 1):S5-S20
-
(2002)
Diabetes Care
, vol.25
, Issue.SUPPL. 1
-
-
-
19
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications part 1: Diagnosis and classification of diabetes mellitus - Provisional report of a WHO consultation
-
Alberti KGMM, Zimmet PZ (1998) Definition, diagnosis and classification of diabetes mellitus and its complications part 1: Diagnosis and classification of diabetes mellitus - Provisional report of a WHO consultation. Diabet Med 15:539-553
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.M.M.1
Zimmet, P.Z.2
-
20
-
-
0028281773
-
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans
-
Orskov C, Rabenhoj L, Wettergren A, Kofod H, Holst JJ (1994) Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans. Diabetes 43:535-539
-
(1994)
Diabetes
, vol.43
, pp. 535-539
-
-
Orskov, C.1
Rabenhoj, L.2
Wettergren, A.3
Kofod, H.4
Holst, J.J.5
-
21
-
-
0037902984
-
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
-
Vilsboll T, Krarup T, Sonne J et al (2003) Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus. J Clin Endocrinol Metab 88:2706-2713
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 2706-2713
-
-
Vilsboll, T.1
Krarup, T.2
Sonne, J.3
-
22
-
-
0021211623
-
The heterogeneity of gastric inhibitory polypeptide in porcine and human gastrointestinal mucosa evaluated with five different antisera
-
Krarup T, Holst JJ (1984) The heterogeneity of gastric inhibitory polypeptide in porcine and human gastrointestinal mucosa evaluated with five different antisera. Regul Pept 9:35-46
-
(1984)
Regul Pept
, vol.9
, pp. 35-46
-
-
Krarup, T.1
Holst, J.J.2
-
23
-
-
0020511159
-
Diminished immunoreactive gastric inhibitory polypeptide response to a meal in newly diagnosed type I (insulin-dependent) diabetics
-
Krarup T, Madsbad S, Moody AJ et al (1983) Diminished immunoreactive gastric inhibitory polypeptide response to a meal in newly diagnosed type I (insulin-dependent) diabetics. J Clin Endocrinol Metab 56:1306-1312
-
(1983)
J Clin Endocrinol Metab
, vol.56
, pp. 1306-1312
-
-
Krarup, T.1
Madsbad, S.2
Moody, A.J.3
-
24
-
-
0033766716
-
Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide
-
Deacon CF, Nauck MA, Meier J, Hucking K, Holst JJ (2000) Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide. J Clin Endocrinol Metab 85:3575-3581
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3575-3581
-
-
Deacon, C.F.1
Nauck, M.A.2
Meier, J.3
Hucking, K.4
Holst, J.J.5
-
25
-
-
0034070572
-
Validation of methods for measurement of insulin secretion in humans in vivo
-
Kjems LL, Christiansen E, Volund A, Bergman RN, Madsbad S (2000) Validation of methods for measurement of insulin secretion in humans in vivo. Diabetes 49:580-588
-
(2000)
Diabetes
, vol.49
, pp. 580-588
-
-
Kjems, L.L.1
Christiansen, E.2
Volund, A.3
Bergman, R.N.4
Madsbad, S.5
-
26
-
-
0026027919
-
Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine
-
Orskov C, Jeppesen J, Madsbad S, Holst JJ (1991) Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine. J Clin Invest 87:415-423
-
(1991)
J Clin Invest
, vol.87
, pp. 415-423
-
-
Orskov, C.1
Jeppesen, J.2
Madsbad, S.3
Holst, J.J.4
-
27
-
-
0021362497
-
Glucagon-related peptides in the human gastrointestinal mucosa
-
Baldissera FGA, Holst JJ (1984) Glucagon-related peptides in the human gastrointestinal mucosa. Diabetologia 26:223-228
-
(1984)
Diabetologia
, vol.26
, pp. 223-228
-
-
Baldissera, F.G.A.1
Holst, J.J.2
-
29
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
30
-
-
0017641399
-
Immunoreactive glucagon (Irg) responses to intravenous glucose in prediabetes and diabetes among pima Indians and normal Caucasians
-
Aronoff SL, Bennett PH, Unger RH (1977) Immunoreactive glucagon (Irg) responses to intravenous glucose in prediabetes and diabetes among pima Indians and normal Caucasians. J Clin Endocrinol Metab 44:968-972
-
(1977)
J Clin Endocrinol Metab
, vol.44
, pp. 968-972
-
-
Aronoff, S.L.1
Bennett, P.H.2
Unger, R.H.3
-
31
-
-
0036227054
-
Intraislet hyperinsulinemia prevents the glucagon response to hypoglycemia despite an intact autonomic response
-
Banarer S, McGregor VP, Cryer PE (2002) Intraislet hyperinsulinemia prevents the glucagon response to hypoglycemia despite an intact autonomic response. Diabetes 51:958-965
-
(2002)
Diabetes
, vol.51
, pp. 958-965
-
-
Banarer, S.1
McGregor, V.P.2
Cryer, P.E.3
-
32
-
-
0015901935
-
Lack of glucagon response to hypoglycemia in diabetes - evidence for an intrinsic pancreatic alpha cell defect
-
Gerich JE, Langlois M, Noacco C, Karam JH, Forsham PH (1973) Lack of glucagon response to hypoglycemia in diabetes - evidence for an intrinsic pancreatic alpha cell defect. Science 182:171-173
-
(1973)
Science
, vol.182
, pp. 171-173
-
-
Gerich, J.E.1
Langlois, M.2
Noacco, C.3
Karam, J.H.4
Forsham, P.H.5
-
33
-
-
33745301045
-
Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion - further evidence for the intraislet insulin hypothesis
-
Meier JJ, Kjems LL, Veldhuis JD, Lefebvre P, Butler PC (2006) Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion - further evidence for the intraislet insulin hypothesis. Diabetes 55:1051-1056
-
(2006)
Diabetes
, vol.55
, pp. 1051-1056
-
-
Meier, J.J.1
Kjems, L.L.2
Veldhuis, J.D.3
Lefebvre, P.4
Butler, P.C.5
-
34
-
-
0023820363
-
The order of islet microvascular cellular perfusion is β-α-δ in the perfused rat pancreas
-
Samols E, Stagner JI, Ewart RBL, Marks V (1988) The order of islet microvascular cellular perfusion is β-α-δ in the perfused rat pancreas. J Clin Invest 82:350-353
-
(1988)
J Clin Invest
, vol.82
, pp. 350-353
-
-
Samols, E.1
Stagner, J.I.2
Ewart, R.B.L.3
Marks, V.4
-
35
-
-
2542532408
-
Regulation of alpha-cell function by the beta-cell during hypoglycemia in Wistar rats: The "switch-off" hypothesis
-
Zhou HR, Tran POT, Yang SL et al (2004) Regulation of alpha-cell function by the beta-cell during hypoglycemia in Wistar rats: the "switch-off" hypothesis. Diabetes 53:1482-1487
-
(2004)
Diabetes
, vol.53
, pp. 1482-1487
-
-
Zhou, H.R.1
Tran, P.O.T.2
Yang, S.L.3
-
36
-
-
0027391607
-
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
-
Nauck MA, Heimesaat MM, Orskov C, Holst JJ, Ebert R, Creutzfeldt W (1993) Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 91:301-307
-
(1993)
J Clin Invest
, vol.91
, pp. 301-307
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Orskov, C.3
Holst, J.J.4
Ebert, R.5
Creutzfeldt, W.6
-
37
-
-
0027248866
-
Normalization of fasting hyperglycemia by exogenous glucagon-like peptide-1 (7-36 amide) in type-2 (non-insulin-dependent) diabetic-patients
-
Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W (1993) Normalization of fasting hyperglycemia by exogenous glucagon-like peptide-1 (7-36 amide) in type-2 (non-insulin-dependent) diabetic-patients. Diabetologia 36:741-744
-
(1993)
Diabetologia
, vol.36
, pp. 741-744
-
-
Nauck, M.A.1
Kleine, N.2
Orskov, C.3
Holst, J.J.4
Willms, B.5
Creutzfeldt, W.6
-
38
-
-
30044441999
-
Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans
-
Meier JJ, Nauck MA, Pott A et al (2006) Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans. Gastroenterology 130:44-54
-
(2006)
Gastroenterology
, vol.130
, pp. 44-54
-
-
Meier, J.J.1
Nauck, M.A.2
Pott, A.3
-
39
-
-
0022389280
-
Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic-islets
-
Schmidt WE, Siegel EG, Creutzfeldt W (1985) Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic-islets. Diabetologia 28:704-707
-
(1985)
Diabetologia
, vol.28
, pp. 704-707
-
-
Schmidt, W.E.1
Siegel, E.G.2
Creutzfeldt, W.3
-
40
-
-
0242499995
-
No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects
-
Sorensen LB, Flint A, Raben A, Hartmann B, Holst JJ, Astrup A (2003) No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects. Int J Obes 27:450-456
-
(2003)
Int J Obes
, vol.27
, pp. 450-456
-
-
Sorensen, L.B.1
Flint, A.2
Raben, A.3
Hartmann, B.4
Holst, J.J.5
Astrup, A.6
-
41
-
-
0020596734
-
Hamster preproglucagon contains the sequence of glucagon and 2 related peptides
-
Bell GI, Santerre RF, Mullenbach GT (1983) Hamster preproglucagon contains the sequence of glucagon and 2 related peptides. Nature 302:716-718
-
(1983)
Nature
, vol.302
, pp. 716-718
-
-
Bell, G.I.1
Santerre, R.F.2
Mullenbach, G.T.3
-
42
-
-
0022971804
-
Glucagon-like peptides Glp-1 and Glp-2, predicted products of the glucagon gene, are secreted separately from pig small-intestine but not pancreas
-
Orskov C, Holst JJ, Khuhtsen S, Baldissera FGA, Poulsen SS, Nielsen OV (1986) Glucagon-like peptides Glp-1 and Glp-2, predicted products of the glucagon gene, are secreted separately from pig small-intestine but not pancreas. Endocrinology 119:1467-1475
-
(1986)
Endocrinology
, vol.119
, pp. 1467-1475
-
-
Orskov, C.1
Holst, J.J.2
Khuhtsen, S.3
Baldissera, F.G.A.4
Poulsen, S.S.5
Nielsen, O.V.6
-
43
-
-
0242383351
-
The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide - regardless of etiology and phenotype
-
Vilsboll T, Knop FK, Krarup T et al (2003) The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide - regardless of etiology and phenotype. J Clin Endocrinol Metab 88:4897-4903
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 4897-4903
-
-
Vilsboll, T.1
Knop, F.K.2
Krarup, T.3
|