메뉴 건너뛰기




Volumn 216, Issue 3, 2013, Pages 297-305

Mitotane induces CYP3A4 expression via activation of the steroid and xenobiotic receptor

Author keywords

Adrenocortical carcinoma; CYP3A4; Mitotane; SXR

Indexed keywords

CYTOCHROME P450 3A4; LUCIFERASE; MESSENGER RNA; MITOTANE; STEROID RECEPTOR; STEROID RECEPTOR COACTIVATOR 1; XENOBIOTIC AGENT;

EID: 84875068550     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-12-0297     Document Type: Article
Times cited : (13)

References (26)
  • 1
    • 33744952176 scopus 로고    scopus 로고
    • Clinical review: adrenocortical carcinoma: clinical update
    • (doi:10.1210/jc.2005-2639)
    • Allolio B & Fassnacht M 2006 Clinical review: adrenocortical carcinoma: clinical update. Journal of Clinical Endocrinology and Metabolism 91 2027-2037. (doi:10.1210/jc.2005-2639)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , pp. 2027-2037
    • Allolio, B.1    Fassnacht, M.2
  • 2
    • 0034465602 scopus 로고    scopus 로고
    • The nuclear corepressors recognize distinct nuclear receptor complexes
    • (doi:10.1210/me.14.6.900)
    • Cohen RN, Putney A, Wondisford FE & Hollenberg AN 2000 The nuclear corepressors recognize distinct nuclear receptor complexes. Molecular Endocrinology 14 900-914. (doi:10.1210/me.14.6.900)
    • (2000) Molecular Endocrinology , vol.14 , pp. 900-914
    • Cohen, R.N.1    Putney, A.2    Wondisford, F.E.3    Hollenberg, A.N.4
  • 3
    • 0022685096 scopus 로고
    • Influence of mitotane on the hypoprothrombinemic effect of warfarin
    • (doi:10.1097/00007611-198603000-00037)
    • Cuddy PG & Loftus LS 1986 Influence of mitotane on the hypoprothrombinemic effect of warfarin. Southern Medical Journal 79 387-388. (doi:10.1097/00007611-198603000-00037)
    • (1986) Southern Medical Journal , vol.79 , pp. 387-388
    • Cuddy, P.G.1    Loftus, L.S.2
  • 6
    • 0015008520 scopus 로고
    • Effects of o,p0-DDD on cortisol and 6-beta-hydroxycortisol secretion and metabolism in man
    • (doi:10.1210/jcem-32-2-192)
    • Fukushima DK, Bradlow HL & Hellman L 1971 Effects of o,p0-DDD on cortisol and 6-beta-hydroxycortisol secretion and metabolism in man. Journal of Clinical Endocrinology and Metabolism 32 192-200. (doi:10.1210/jcem-32-2-192)
    • (1971) Journal of Clinical Endocrinology and Metabolism , vol.32 , pp. 192-200
    • Fukushima, D.K.1    Bradlow, H.L.2    Hellman, L.3
  • 7
    • 78649576502 scopus 로고    scopus 로고
    • Pregnane X receptor and constitutive androstane receptor at the crossroads of drug metabolism and energy metabolism
    • (doi:10.1124/dmd.110. 035568)
    • Gao J & Xie W 2010 Pregnane X receptor and constitutive androstane receptor at the crossroads of drug metabolism and energy metabolism. Drug Metabolism and Disposition 38 2091-2095. (doi:10.1124/dmd.110. 035568)
    • (2010) Drug Metabolism and Disposition , vol.38 , pp. 2091-2095
    • Gao, J.1    Xie, W.2
  • 8
    • 0032702726 scopus 로고    scopus 로고
    • The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module
    • Goodwin B, Hodgson E & Liddle C 1999 The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module. Molecular Pharmacology 56 1329-1339.
    • (1999) Molecular Pharmacology , vol.56 , pp. 1329-1339
    • Goodwin, B.1    Hodgson, E.2    Liddle, C.3
  • 9
    • 0024390153 scopus 로고
    • Hepatic microsomal enzyme induction and adrenal crisis due to o,p'DDD therapy for metastatic adrenocortical carcinoma
    • (doi:10.1111/j.1365-2265.1989.tb00453.x)
    • Hague RV, May W & Cullen DR 1989 Hepatic microsomal enzyme induction and adrenal crisis due to o,p'DDD therapy for metastatic adrenocortical carcinoma. Clinical Endocrinology 31 51-57. (doi:10.1111/j.1365-2265.1989.tb00453.x)
    • (1989) Clinical Endocrinology , vol.31 , pp. 51-57
    • Hague, R.V.1    May, W.2    Cullen, D.R.3
  • 10
    • 37549004782 scopus 로고    scopus 로고
    • HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans
    • (doi:10.1124/dmd.107.017418)
    • Kanebratt KP & Andersson TB 2008 HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans. Drug Metabolism and Disposition 36 137-145. (doi:10.1124/dmd.107.017418)
    • (2008) Drug Metabolism and Disposition , vol.36 , pp. 137-145
    • Kanebratt, K.P.1    Andersson, T.B.2
  • 11
    • 0036799870 scopus 로고    scopus 로고
    • The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism
    • (doi:10.1210/er.2001-0038)
    • Kliewer SA, Goodwin B & Willson TM 2002 The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocrine Reviews 23 687-702. (doi:10.1210/er.2001-0038)
    • (2002) Endocrine Reviews , vol.23 , pp. 687-702
    • Kliewer, S.A.1    Goodwin, B.2    Willson, T.M.3
  • 12
    • 80054769146 scopus 로고    scopus 로고
    • Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma
    • (doi:10.1111/j.1365-2265.2011.04214.x)
    • Kroiss M, Quinkler M, Lutz WK, Allolio B & Fassnacht M 2011 Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma. Clinical Endocrinology 75 585-591. (doi:10.1111/j.1365-2265.2011.04214.x)
    • (2011) Clinical Endocrinology , vol.75 , pp. 585-591
    • Kroiss, M.1    Quinkler, M.2    Lutz, W.K.3    Allolio, B.4    Fassnacht, M.5
  • 14
    • 15744384408 scopus 로고    scopus 로고
    • Transcriptional induction of CYP3A4 by o,p0-DDT in HepG2 cells
    • (doi:10.1016/ j.toxlet.2005.01.003)
    • Medina-Diaz IM & Elizondo G 2005 Transcriptional induction of CYP3A4 by o,p0-DDT in HepG2 cells. Toxicology Letters 157 41-47. (doi:10.1016/ j.toxlet.2005.01.003)
    • (2005) Toxicology Letters , vol.157 , pp. 41-47
    • Medina-Diaz, I.M.1    Elizondo, G.2
  • 18
    • 1442351143 scopus 로고    scopus 로고
    • Coregulator function: a key to understanding tissue specificity of selective receptor modulators
    • (doi:10.1210/er.2003-0023)
    • Smith CL & O'Malley BW 2004 Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocrine Reviews 25 45-71. (doi:10.1210/er.2003-0023)
    • (2004) Endocrine Reviews , vol.25 , pp. 45-71
    • Smith, C.L.1    O'Malley, B.W.2
  • 19
    • 33749860753 scopus 로고    scopus 로고
    • The endocrine disrupting chemical, diethylhexyl phthalate, activates MDR1 gene expression in human colon cancer LS174T cells
    • (doi:10.1677/joe.1.06664)
    • Takeshita A, Inagaki K, Igarashi-Migitaka J, Ozawa Y & Koibuchi N 2006 The endocrine disrupting chemical, diethylhexyl phthalate, activates MDR1 gene expression in human colon cancer LS174T cells. Journal of Endocrinology 190 897-902. (doi:10.1677/joe.1.06664)
    • (2006) Journal of Endocrinology , vol.190 , pp. 897-902
    • Takeshita, A.1    Inagaki, K.2    Igarashi-Migitaka, J.3    Ozawa, Y.4    Koibuchi, N.5
  • 20
    • 80053437888 scopus 로고    scopus 로고
    • Acetyl tributyl citrate, the most widely used phthalate substitute plasticizer, induces cytochrome p450 3a through steroid and xenobiotic receptor
    • (doi:10.1093/ toxsci/kfr178)
    • Takeshita A, Igarashi-Migitaka J, Nishiyama K, Takahashi H, Takeuchi Y & Koibuchi N 2011 Acetyl tributyl citrate, the most widely used phthalate substitute plasticizer, induces cytochrome p450 3a through steroid and xenobiotic receptor. Toxicological Sciences 123 460-470. (doi:10.1093/ toxsci/kfr178)
    • (2011) Toxicological Sciences , vol.123 , pp. 460-470
    • Takeshita, A.1    Igarashi-Migitaka, J.2    Nishiyama, K.3    Takahashi, H.4    Takeuchi, Y.5    Koibuchi, N.6
  • 21
    • 78650175257 scopus 로고    scopus 로고
    • Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR
    • (doi:10.1016/j.addr.2010.08.006)
    • Tolson AH & Wang H 2010 Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR. Advanced Drug Delivery Reviews 62 1238-1249. (doi:10.1016/j.addr.2010.08.006)
    • (2010) Advanced Drug Delivery Reviews , vol.62 , pp. 1238-1249
    • Tolson, A.H.1    Wang, H.2
  • 22
    • 52449133102 scopus 로고    scopus 로고
    • CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme
    • (doi:10.2174/138920008785821710)
    • Wang H & Tompkins LM 2008 CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. Current Drug Metabolism 9 598-610. (doi:10.2174/138920008785821710)
    • (2008) Current Drug Metabolism , vol.9 , pp. 598-610
    • Wang, H.1    Tompkins, L.M.2
  • 24
    • 61549104490 scopus 로고    scopus 로고
    • PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics
    • (doi:10.2217/14622416.9.11.1695)
    • Zhang B, XieW& KrasowskiMD 2008 PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics. Pharmacogenomics 9 1695-1709. (doi:10.2217/14622416.9.11.1695)
    • (2008) Pharmacogenomics , vol.9 , pp. 1695-1709
    • Zhang, B.1    Xie, W.2    Krasowski, M.D.3
  • 25
    • 65349091444 scopus 로고    scopus 로고
    • The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism
    • (doi:10.1621/nrs.07001)
    • Zhou C, Verma S & Blumberg B 2009 The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. Nuclear Receptor Signaling 7 e001. (doi:10.1621/nrs.07001)
    • (2009) Nuclear Receptor Signaling , vol.7
    • Zhou, C.1    Verma, S.2    Blumberg, B.3
  • 26
    • 23444453717 scopus 로고    scopus 로고
    • Regulation of Bcl-2 and Bcl-xL anti-apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes
    • (doi:10.1016/ j.bbamcr.2005.02.005)
    • Zucchini N, de Sousa G, Bailly-Maitre B, Gugenheim J, Bars R, Lemaire G & Rahmani R 2005 Regulation of Bcl-2 and Bcl-xL anti-apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes. Biochimica et Biophysica Acta 1745 48-58. (doi:10.1016/ j.bbamcr.2005.02.005)
    • (2005) Biochimica et Biophysica Acta , vol.1745 , pp. 48-58
    • Zucchini, N.1    De Sousa, G.2    Bailly-Maitre, B.3    Gugenheim, J.4    Bars, R.5    Lemaire, G.6    Rahmani, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.