-
1
-
-
62849092993
-
Effects of the mycotoxin fumonisin B(1) on cell death in human kidney cells and human lung fibroblasts in primary culture
-
Schwerdt, G., Konigs, M., Holzinger, H., Humpf, H. U. et al., Effects of the mycotoxin fumonisin B(1) on cell death in human kidney cells and human lung fibroblasts in primary culture. J. Appl. Toxicol. 2009, 29, 174-182.
-
(2009)
J. Appl. Toxicol.
, vol.29
, pp. 174-182
-
-
Schwerdt, G.1
Konigs, M.2
Holzinger, H.3
Humpf, H.U.4
-
2
-
-
0035009801
-
An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme
-
Voss, K. A., Riley, R. T., Norred, W. P., Bacon, C. W. et al., An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. Environ. Health Persp. 2001, 109, 259-266.
-
(2001)
Environ. Health Persp.
, vol.109
, pp. 259-266
-
-
Voss, K.A.1
Riley, R.T.2
Norred, W.P.3
Bacon, C.W.4
-
3
-
-
33746734266
-
Fumonisin concentration and ceramide synthase inhibitory activity of corn, masa, and tortilla chips
-
Voss, K. A., Norred, W. P., Meredith, F. I., Riley, R. T. et al., Fumonisin concentration and ceramide synthase inhibitory activity of corn, masa, and tortilla chips. J. Toxicol. Env. Health A 2006, 69, 1387-1397.
-
(2006)
J. Toxicol. Env. Health A
, vol.69
, pp. 1387-1397
-
-
Voss, K.A.1
Norred, W.P.2
Meredith, F.I.3
Riley, R.T.4
-
4
-
-
74049147153
-
Mycotoxins and human disease: a largely ignored global health issue
-
Wild, C. P., Gong, Y. Y., Mycotoxins and human disease: a largely ignored global health issue. Carcinogenesis 2009, 31, 71-82.
-
(2009)
Carcinogenesis
, vol.31
, pp. 71-82
-
-
Wild, C.P.1
Gong, Y.Y.2
-
5
-
-
0026317132
-
Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme
-
Wang, E., Norred, W. P., Bacon, C. W., Riley, R. T. et al., Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. J. Biol. Chem. 1991, 266, 14486-14490.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 14486-14490
-
-
Wang, E.1
Norred, W.P.2
Bacon, C.W.3
Riley, R.T.4
-
6
-
-
64149110203
-
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals
-
Zitomer, N. C., Mitchell, T., Voss, K. A., Bondy, G. S. et al., Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals. J. Biol. Chem. 2009, 284, 4786-4795.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 4786-4795
-
-
Zitomer, N.C.1
Mitchell, T.2
Voss, K.A.3
Bondy, G.S.4
-
7
-
-
66349108431
-
Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease
-
Merrill, A. H., Jr., Stokes, T. H., Momin, A., Park, H. et al., Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease. J. Lipid Res. 2009, 50, S97-S102.
-
(2009)
J. Lipid Res.
, vol.50
-
-
Merrill Jr, A.H.1
Stokes, T.H.2
Momin, A.3
Park, H.4
-
8
-
-
11144357212
-
Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize
-
Marasas, W. F., Riley, R. T., Hendricks, K. A., Stevens, V. L. et al., Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize. J. Nutr. 2004, 134, 711-716.
-
(2004)
J. Nutr.
, vol.134
, pp. 711-716
-
-
Marasas, W.F.1
Riley, R.T.2
Hendricks, K.A.3
Stevens, V.L.4
-
9
-
-
33748746334
-
When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: insights into the regulation of ceramide synthesis
-
Pewzner-Jung, Y., Ben-Dor, S., Futerman, A. H., When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: insights into the regulation of ceramide synthesis. J. Biol. Chem. 2006, 281, 25001-25005.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 25001-25005
-
-
Pewzner-Jung, Y.1
Ben-Dor, S.2
Futerman, A.H.3
-
10
-
-
77953561361
-
Mammalian ceramide synthases
-
Levy, M., Futerman, A. H., Mammalian ceramide synthases. IUBMB Life 62, 347-356.
-
IUBMB Life
, vol.62
, pp. 347-356
-
-
Levy, M.1
Futerman, A.H.2
-
11
-
-
7244244035
-
Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas
-
Koybasi, S., Senkal, C. E., Sundararaj, K., Spassieva, S. et al., Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas. J. Biol. Chem. 2004, 279, 44311-44319.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44311-44319
-
-
Koybasi, S.1
Senkal, C.E.2
Sundararaj, K.3
Spassieva, S.4
-
12
-
-
4444309565
-
The complex life of simple sphingolipids
-
Futerman, A. H., Hannun, Y. A., The complex life of simple sphingolipids. EMBO Rep. 2004, 5, 777-782.
-
(2004)
EMBO Rep.
, vol.5
, pp. 777-782
-
-
Futerman, A.H.1
Hannun, Y.A.2
-
13
-
-
33847376437
-
Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas
-
Senkal, C. E., Ponnusamy, S., Rossi, M. J., Bialewski, J. et al., Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas. Mol. Cancer Ther. 2007, 6, 712-722.
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 712-722
-
-
Senkal, C.E.1
Ponnusamy, S.2
Rossi, M.J.3
Bialewski, J.4
-
14
-
-
72949118520
-
Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression
-
Erez-Roman, R., Pienik, R., Futerman, A. H., Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression. Biochem. Biophys. Res. Commun. 2010, 391, 219-223.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 219-223
-
-
Erez-Roman, R.1
Pienik, R.2
Futerman, A.H.3
-
15
-
-
65549143292
-
Ceramide synthases and ceramide levels are increased in breast cancer tissue
-
Schiffmann, S., Sandner, J., Birod, K., Wobst, I. et al., Ceramide synthases and ceramide levels are increased in breast cancer tissue. Carcinogenesis 2009, 30, 745-752.
-
(2009)
Carcinogenesis
, vol.30
, pp. 745-752
-
-
Schiffmann, S.1
Sandner, J.2
Birod, K.3
Wobst, I.4
-
16
-
-
0032563093
-
Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor
-
Humpf, H. U., Schmelz, E. M., Meredith, F. I., Vesper, H. et al., Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. J. Biol. Chem. 1998, 273, 19060-19064.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19060-19064
-
-
Humpf, H.U.1
Schmelz, E.M.2
Meredith, F.I.3
Vesper, H.4
-
17
-
-
34948900878
-
Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites
-
Seiferlein, M., Humpf, H. U., Voss, K. A., Sullards, M. C. et al., Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites. Mol. Nutr. Food Res. 2007, 51, 1120-1130.
-
(2007)
Mol. Nutr. Food Res.
, vol.51
, pp. 1120-1130
-
-
Seiferlein, M.1
Humpf, H.U.2
Voss, K.A.3
Sullards, M.C.4
-
18
-
-
41949140023
-
Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
-
Laviad, E. L., Albee, L., Pankova-Kholmyansky, I., Epstein, S. et al., Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J. Biol. Chem. 2008, 283, 5677-5684.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5677-5684
-
-
Laviad, E.L.1
Albee, L.2
Pankova-Kholmyansky, I.3
Epstein, S.4
-
19
-
-
33751499576
-
Isolation of the Fumonisin Mycotoxins - a quantitative approach
-
Cawood, M. E., Gelderblom, W. C. A., Vleggaar, R., Behrend, Y. et al., Isolation of the Fumonisin Mycotoxins - a quantitative approach. J. Agr. Food Chem. 1991, 39, 1958-1962.
-
(1991)
J. Agr. Food Chem.
, vol.39
, pp. 1958-1962
-
-
Cawood, M.E.1
Gelderblom, W.C.A.2
Vleggaar, R.3
Behrend, Y.4
-
20
-
-
0018247640
-
Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor
-
Wigler, M., Pellicer, A., Silverstein, S., Axel, R., Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor. Cell 1978, 14, 725-731.
-
(1978)
Cell
, vol.14
, pp. 725-731
-
-
Wigler, M.1
Pellicer, A.2
Silverstein, S.3
Axel, R.4
-
21
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K. et al., Measurement of protein using bicinchoninic acid. Anal. Biochem. 1985, 150, 76-85.
-
(1985)
Anal. Biochem.
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
-
22
-
-
23944483995
-
Mammalian Lass6 and its related family members regulate synthesis of specific ceramides
-
Mizutani, Y., Kihara, A., Igarashi, Y., Mammalian Lass6 and its related family members regulate synthesis of specific ceramides. Biochem. J. 2005, 390, 263-271.
-
(2005)
Biochem. J.
, vol.390
, pp. 263-271
-
-
Mizutani, Y.1
Kihara, A.2
Igarashi, Y.3
-
23
-
-
33748747214
-
LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity
-
Mizutani, Y., Kihara, A., Igarashi, Y., LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity. Biochem. J. 2006, 398, 531-538.
-
(2006)
Biochem. J.
, vol.398
, pp. 531-538
-
-
Mizutani, Y.1
Kihara, A.2
Igarashi, Y.3
-
24
-
-
41949140023
-
Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
-
Laviad, E. L., Albee, L., Pankova-Kholmyansky, I., Epstein, S. et al., Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J. Biol. Chem. 2008, 283, 5677-5684.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5677-5684
-
-
Laviad, E.L.1
Albee, L.2
Pankova-Kholmyansky, I.3
Epstein, S.4
-
25
-
-
10644246050
-
Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells
-
Sharma, N., He, Q., Sharma, R. P., Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells. Chem. Biol. Interact. 2004, 151, 33-42.
-
(2004)
Chem. Biol. Interact.
, vol.151
, pp. 33-42
-
-
Sharma, N.1
He, Q.2
Sharma, R.P.3
-
26
-
-
0033558227
-
Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells
-
Hung, W. C., Chang, H. C., Chuang, L. Y., Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells. Biochem. J. 1999, 338, 161-166.
-
(1999)
Biochem. J.
, vol.338
, pp. 161-166
-
-
Hung, W.C.1
Chang, H.C.2
Chuang, L.Y.3
-
27
-
-
0036133167
-
DNA damage in human fibroblasts exposed to fumonisin B(1)
-
Galvano, F., Russo, A., Cardile, V., Galvano, G. et al., DNA damage in human fibroblasts exposed to fumonisin B(1). Food Chem. Toxicol. 2002, 40, 25-31.
-
(2002)
Food Chem. Toxicol.
, vol.40
, pp. 25-31
-
-
Galvano, F.1
Russo, A.2
Cardile, V.3
Galvano, G.4
-
28
-
-
0025323466
-
Effects of Fusarium moniliforme and corn associated with equine leukoencephalomalacia on rat neurotransmitters and metabolites
-
Porter, J. K., Voss, K. A., Bacon, C. W., Norred, W. P., Effects of Fusarium moniliforme and corn associated with equine leukoencephalomalacia on rat neurotransmitters and metabolites. Proc. Soc. Exp. Biol. Med. 1990, 194, 265-269.
-
(1990)
Proc. Soc. Exp. Biol. Med.
, vol.194
, pp. 265-269
-
-
Porter, J.K.1
Voss, K.A.2
Bacon, C.W.3
Norred, W.P.4
-
29
-
-
0024194145
-
Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme
-
Marasas, W. F., Kellerman, T. S., Gelderblom, W. C., Coetzer, J. A. et al., Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme. Onderstepoort. J. Vet. Res. 1988, 55, 197-203.
-
(1988)
Onderstepoort. J. Vet. Res.
, vol.55
, pp. 197-203
-
-
Marasas, W.F.1
Kellerman, T.S.2
Gelderblom, W.C.3
Coetzer, J.A.4
-
30
-
-
0024605622
-
Hepatotoxicity and renal toxicity in rats of corn samples associated with field cases of equine leukoencephalomalacia
-
Voss, K. A., Norred, W. P., Plattner, R. D., Bacon, C. W., Hepatotoxicity and renal toxicity in rats of corn samples associated with field cases of equine leukoencephalomalacia. Food Chem. Toxicol. 1989, 27, 89-96.
-
(1989)
Food Chem. Toxicol.
, vol.27
, pp. 89-96
-
-
Voss, K.A.1
Norred, W.P.2
Plattner, R.D.3
Bacon, C.W.4
-
31
-
-
0027511687
-
Programmed cell death induced by ceramide
-
Obeid, L. M., Linardic, C. M., Karolak, L. A., Hannun, Y. A., Programmed cell death induced by ceramide. Science 1993, 259, 1769-1771.
-
(1993)
Science
, vol.259
, pp. 1769-1771
-
-
Obeid, L.M.1
Linardic, C.M.2
Karolak, L.A.3
Hannun, Y.A.4
-
32
-
-
0034470251
-
Ceramide as an activator lipid of cathepsin D
-
Heinrich, M., Wickel, M., Winoto-Morbach, S., Schneider-Brachert, W. et al., Ceramide as an activator lipid of cathepsin D. Adv. Exp. Med. Biol. 2000, 477, 305-315.
-
(2000)
Adv. Exp. Med. Biol.
, vol.477
, pp. 305-315
-
-
Heinrich, M.1
Wickel, M.2
Winoto-Morbach, S.3
Schneider-Brachert, W.4
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