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Volumn 38, Issue 4, 2013, Pages 542-551

Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice

Author keywords

5 reductase; D1 like receptors; D2 like receptors; Dopamine; Finasteride; Prepulse inhibition of the startle

Indexed keywords

3 ALLYL 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; APOMORPHINE; FINASTERIDE; QUINPIROLE; STEROID 5ALPHA REDUCTASE;

EID: 84875052255     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2012.07.014     Document Type: Article
Times cited : (36)

References (71)
  • 3
    • 0032448780 scopus 로고    scopus 로고
    • Neurosteroids: a novel function of the brain
    • Baulieu E.E. Neurosteroids: a novel function of the brain. Psychoneuroendocrinology 1998, 23:963-987.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 963-987
    • Baulieu, E.E.1
  • 4
    • 0025859189 scopus 로고
    • Behavioural differences between artificially selected aggressive and non-aggressive mice: response to apomorphine
    • Benus R.F., Bohus B., Koolhaas J.M., van Oortmerssen G.A. Behavioural differences between artificially selected aggressive and non-aggressive mice: response to apomorphine. Behav. Brain Res. 1991, 43:203-208.
    • (1991) Behav. Brain Res. , vol.43 , pp. 203-208
    • Benus, R.F.1    Bohus, B.2    Koolhaas, J.M.3    van Oortmerssen, G.A.4
  • 6
    • 0024810657 scopus 로고
    • 2 dopamine agonists in intact rats
    • 2 dopamine agonists in intact rats. Brain Res. 1989, 504:276-283.
    • (1989) Brain Res. , vol.504 , pp. 276-283
    • Bordi, F.1    Meller, E.2
  • 8
    • 38449090172 scopus 로고    scopus 로고
    • Treatment of Tourette's syndrome with finasteride
    • Bortolato M., Muroni A., Marrosu F. Treatment of Tourette's syndrome with finasteride. Am. J. Psychiatry 2007, 164:1914-1915.
    • (2007) Am. J. Psychiatry , vol.164 , pp. 1914-1915
    • Bortolato, M.1    Muroni, A.2    Marrosu, F.3
  • 10
    • 0025190458 scopus 로고
    • Sensorimotor gating and schizophrenia. Human and animal model studies
    • Braff D.L., Geyer M.A. Sensorimotor gating and schizophrenia. Human and animal model studies. Arch. Gen. Psychiatry 1990, 47:181-188.
    • (1990) Arch. Gen. Psychiatry , vol.47 , pp. 181-188
    • Braff, D.L.1    Geyer, M.A.2
  • 12
    • 0022994928 scopus 로고
    • 2 receptor interaction in the generation of dopamine agonist related behaviors
    • 2 receptor interaction in the generation of dopamine agonist related behaviors. Eur. J. Pharmacol. 1986, 131:301-306.
    • (1986) Eur. J. Pharmacol. , vol.131 , pp. 301-306
    • Braun, A.R.1    Chase, T.N.2
  • 17
    • 46249114635 scopus 로고    scopus 로고
    • Examining cortisol rhythmicity and responsivity to stress in children with Tourette syndrome
    • Corbett B.A., Mendoza S.P., Baym C.L., Bunge S.A., Levine S. Examining cortisol rhythmicity and responsivity to stress in children with Tourette syndrome. Psychoneuroendocrinology 2008, 33:810-820.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 810-820
    • Corbett, B.A.1    Mendoza, S.P.2    Baym, C.L.3    Bunge, S.A.4    Levine, S.5
  • 18
    • 0022545319 scopus 로고
    • Differential effects of dopamine agonists on acoustically and electrically elicited startle responses: comparison to effects of strychnine
    • Davis M., Commissaris R.L., Cassella J.V., Yang S., Dember L., Harty T.P. Differential effects of dopamine agonists on acoustically and electrically elicited startle responses: comparison to effects of strychnine. Brain Res. 1986, 371:58-69.
    • (1986) Brain Res. , vol.371 , pp. 58-69
    • Davis, M.1    Commissaris, R.L.2    Cassella, J.V.3    Yang, S.4    Dember, L.5    Harty, T.P.6
  • 19
    • 84865566076 scopus 로고    scopus 로고
    • Inhibition of 5alpha-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation
    • doi:10.1016/j.psyneuen.2011.09.018 in press
    • Devoto, P., Frau, R., Bini, V., Pillolla, G., Saba, P., Flore, G., Corona, M., Marrosu, F., Bortolato, M. Inhibition of 5alpha-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation. Psychoneuroendocrinology, , in press. doi:10.1016/j.psyneuen.2011.09.018.
    • Psychoneuroendocrinology
    • Devoto, P.1    Frau, R.2    Bini, V.3    Pillolla, G.4    Saba, P.5    Flore, G.6    Corona, M.7    Marrosu, F.8    Bortolato, M.9
  • 20
    • 0028258221 scopus 로고
    • Modulation of brain dopamine transmission by sex steroids
    • Di Paolo T. Modulation of brain dopamine transmission by sex steroids. Rev. Neurosci. 1994, 5:27-41.
    • (1994) Rev. Neurosci. , vol.5 , pp. 27-41
    • Di Paolo, T.1
  • 24
    • 34250847013 scopus 로고    scopus 로고
    • Neurosteroids, neuroactive steroids, and symptoms of affective disorders
    • Dubrovsky B. Neurosteroids, neuroactive steroids, and symptoms of affective disorders. Pharmacol. Biochem. Behav. 2006, 84:644-655.
    • (2006) Pharmacol. Biochem. Behav. , vol.84 , pp. 644-655
    • Dubrovsky, B.1
  • 25
    • 79956335023 scopus 로고    scopus 로고
    • 2 receptor subtypes in the dorsomedial striatum but not the nucleus accumbens core during behavioral inhibition in the stop-signal task in rats
    • 2 receptor subtypes in the dorsomedial striatum but not the nucleus accumbens core during behavioral inhibition in the stop-signal task in rats. J. Neurosci. 2011, 31:7349-7356.
    • (2011) J. Neurosci. , vol.31 , pp. 7349-7356
    • Eagle, D.M.1    Wong, J.C.2    Allan, M.E.3    Mar, A.C.4    Theobald, D.E.5    Robbins, T.W.6
  • 27
    • 70350337441 scopus 로고    scopus 로고
    • Infusions of anti-sense oligonucleotides for DARPP-32 to the ventral tegmental area reduce effects of progesterone- and a dopamine type 1-like receptor agonist to facilitate lordosis
    • Frye C.A., Walf A.A. Infusions of anti-sense oligonucleotides for DARPP-32 to the ventral tegmental area reduce effects of progesterone- and a dopamine type 1-like receptor agonist to facilitate lordosis. Behav. Brain Res. 2010, 206:286-292.
    • (2010) Behav. Brain Res. , vol.206 , pp. 286-292
    • Frye, C.A.1    Walf, A.A.2
  • 30
    • 0034917841 scopus 로고    scopus 로고
    • Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review
    • Geyer M.A., Krebs-Thomson K., Braff D.L., Swerdlow N.R. Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology 2001, 156:117-154.
    • (2001) Psychopharmacology , vol.156 , pp. 117-154
    • Geyer, M.A.1    Krebs-Thomson, K.2    Braff, D.L.3    Swerdlow, N.R.4
  • 31
    • 38049073282 scopus 로고    scopus 로고
    • The ventral striatum as an interface between the limbic and motor systems
    • Groenewegen H.J., Trimble M. The ventral striatum as an interface between the limbic and motor systems. CNS Spectr. 2007, 12:887-892.
    • (2007) CNS Spectr. , vol.12 , pp. 887-892
    • Groenewegen, H.J.1    Trimble, M.2
  • 32
    • 0037376939 scopus 로고    scopus 로고
    • Gender differences in schizophrenia
    • Häfner H. Gender differences in schizophrenia. Psychoneuroendocrinology 2003, (Suppl. 2):17-54.
    • (2003) Psychoneuroendocrinology , Issue.SUPPL. 2 , pp. 17-54
    • Häfner, H.1
  • 33
  • 34
    • 0028169945 scopus 로고
    • 2 dopamine receptor antagonists reverse prepulse inhibition deficits in an animal model of schizophrenia
    • 2 dopamine receptor antagonists reverse prepulse inhibition deficits in an animal model of schizophrenia. Psychopharmacology 1994, 115:447-453.
    • (1994) Psychopharmacology , vol.115 , pp. 447-453
    • Hoffman, D.C.1    Donovan, H.2
  • 36
    • 34548516132 scopus 로고    scopus 로고
    • Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice
    • Kalueff A.V., Jensen C.L., Murphy DL Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice. Brain Res. 2007, 1169:87-97.
    • (2007) Brain Res. , vol.1169 , pp. 87-97
    • Kalueff, A.V.1    Jensen, C.L.2    Murphy, D.L.3
  • 37
    • 0032714462 scopus 로고    scopus 로고
    • Gender differences in brain and behavior: hormonal and neural bases
    • Kelly S.J., Ostrowski N.L., Wilson M.A. Gender differences in brain and behavior: hormonal and neural bases. Pharmacol. Biochem. Behav. 1999, 64:655-664.
    • (1999) Pharmacol. Biochem. Behav. , vol.64 , pp. 655-664
    • Kelly, S.J.1    Ostrowski, N.L.2    Wilson, M.A.3
  • 38
    • 0033169096 scopus 로고    scopus 로고
    • Rat strain differences in the ability to disrupt sensorimotor gating are limited to the dopaminergic system, specific to prepulse inhibition, and unrelated to changes in startle amplitude or nucleus accumbens dopamine receptor sensitivity
    • Kinney G.G., Wilkinson L.O., Saywell K.L., Tricklebank M.D. Rat strain differences in the ability to disrupt sensorimotor gating are limited to the dopaminergic system, specific to prepulse inhibition, and unrelated to changes in startle amplitude or nucleus accumbens dopamine receptor sensitivity. J. Neurosci. 1999, 19:5644-5653.
    • (1999) J. Neurosci. , vol.19 , pp. 5644-5653
    • Kinney, G.G.1    Wilkinson, L.O.2    Saywell, K.L.3    Tricklebank, M.D.4
  • 39
    • 44849089776 scopus 로고    scopus 로고
    • Improvement of general symptoms in a chronic psychotic patient treated with finasteride: case report
    • Koethe D., Bortolato M., Piomelli D., Leweke F.M. Improvement of general symptoms in a chronic psychotic patient treated with finasteride: case report. Pharmacopsychiatry 2008, 41:115-116.
    • (2008) Pharmacopsychiatry , vol.41 , pp. 115-116
    • Koethe, D.1    Bortolato, M.2    Piomelli, D.3    Leweke, F.M.4
  • 42
    • 0033903439 scopus 로고    scopus 로고
    • 2 receptor agonist, does not reduce prepulse inhibition of the startle reflex in rats
    • 2 receptor agonist, does not reduce prepulse inhibition of the startle reflex in rats. Psychopharmacology 2000, 151:38-48.
    • (2000) Psychopharmacology , vol.151 , pp. 38-48
    • Martin-Iverson, M.T.1    Else, D.2
  • 43
    • 0027729679 scopus 로고
    • Androgen and progesterone metabolism in the central and peripheral nervous system
    • Martini L., Melcangi R.C., Maggi R. Androgen and progesterone metabolism in the central and peripheral nervous system. J. Steroid Biochem. Mol. Biol. 1993, 47:195-205.
    • (1993) J. Steroid Biochem. Mol. Biol. , vol.47 , pp. 195-205
    • Martini, L.1    Melcangi, R.C.2    Maggi, R.3
  • 44
    • 0030011874 scopus 로고    scopus 로고
    • Testosterone and progesterone metabolism in the central nervous system: cellular localization and mechanism of control of the enzymes involved
    • Martini L., Celotti F., Melcangi R.C. Testosterone and progesterone metabolism in the central nervous system: cellular localization and mechanism of control of the enzymes involved. Cell. Mol. Neurobiol. 1996, 16:271-282.
    • (1996) Cell. Mol. Neurobiol. , vol.16 , pp. 271-282
    • Martini, L.1    Celotti, F.2    Melcangi, R.C.3
  • 46
    • 0036184586 scopus 로고    scopus 로고
    • Are cognitive impairments associated with sensitivity to stress in schizophrenia? An experience sampling study
    • Myin-Germeys I., Krabbendam L., Jolles J., Delespaul P.A., van Os J. Are cognitive impairments associated with sensitivity to stress in schizophrenia? An experience sampling study. Am. J. Psychiatry. 2002, 159:443-449.
    • (2002) Am. J. Psychiatry. , vol.159 , pp. 443-449
    • Myin-Germeys, I.1    Krabbendam, L.2    Jolles, J.3    Delespaul, P.A.4    van Os, J.5
  • 48
    • 79953325748 scopus 로고    scopus 로고
    • Steroid 5α-reductase as a novel therapeutic target for schizophrenia and other neuropsychiatric disorders
    • Paba S., Frau R., Godar S.C., Devoto P., Marrosu F., Bortolato M. Steroid 5α-reductase as a novel therapeutic target for schizophrenia and other neuropsychiatric disorders. Curr. Pharm. Des. 2011, 17:151-167.
    • (2011) Curr. Pharm. Des. , vol.17 , pp. 151-167
    • Paba, S.1    Frau, R.2    Godar, S.C.3    Devoto, P.4    Marrosu, F.5    Bortolato, M.6
  • 49
    • 0036459963 scopus 로고    scopus 로고
    • Strain differences in sigma(1) receptor-mediated behaviours are related to neurosteroid levels
    • Phan V.L., Urani A., Romieu P., Maurice T. Strain differences in sigma(1) receptor-mediated behaviours are related to neurosteroid levels. Eur. J. Neurosci. 2002, 15:1523-1534.
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 1523-1534
    • Phan, V.L.1    Urani, A.2    Romieu, P.3    Maurice, T.4
  • 50
    • 33646580410 scopus 로고    scopus 로고
    • In the ventral tegmental area, G-proteins mediate progesterone's actions at dopamine type 1 receptors for lordosis of rats and hamsters
    • Petralia S.M., Frye C.A. In the ventral tegmental area, G-proteins mediate progesterone's actions at dopamine type 1 receptors for lordosis of rats and hamsters. Psychopharmacology (Berl.) 2006, 186:133-142.
    • (2006) Psychopharmacology (Berl.) , vol.186 , pp. 133-142
    • Petralia, S.M.1    Frye, C.A.2
  • 53
    • 13244295493 scopus 로고    scopus 로고
    • 2 agonist effects on prepulse inhibition and locomotion: comparison of Sprague-Dawley rats to Swiss-Webster, 129X1/SvJ, C57BL/6J, and DBA/2J mice
    • 2 agonist effects on prepulse inhibition and locomotion: comparison of Sprague-Dawley rats to Swiss-Webster, 129X1/SvJ, C57BL/6J, and DBA/2J mice. J. Pharmacol. Exp. Ther. 2005, 312:733-741.
    • (2005) J. Pharmacol. Exp. Ther. , vol.312 , pp. 733-741
    • Ralph, R.J.1    Caine, S.B.2
  • 54
    • 33847619835 scopus 로고    scopus 로고
    • 2-like agonists on prepulse inhibition of startle in inbred C3H/HeJ, SPRET/EiJ, and CAST/EiJ mice
    • 2-like agonists on prepulse inhibition of startle in inbred C3H/HeJ, SPRET/EiJ, and CAST/EiJ mice. Psychopharmacology 2007, 191:731-739.
    • (2007) Psychopharmacology , vol.191 , pp. 731-739
    • Ralph, R.J.1    Caine, S.B.2
  • 57
    • 79953645858 scopus 로고    scopus 로고
    • Dopamine receptor signaling: intracellular pathways to behavior
    • Humana, Totawa, K.A. Neve (Ed.)
    • Romanelli R.J., Williams J.T., Neve K.A. Dopamine receptor signaling: intracellular pathways to behavior. The Dopamine Receptors 2010, 137-173. Humana, Totawa. 2nd ed. K.A. Neve (Ed.).
    • (2010) The Dopamine Receptors , pp. 137-173
    • Romanelli, R.J.1    Williams, J.T.2    Neve, K.A.3
  • 58
    • 0035225999 scopus 로고    scopus 로고
    • Neuroactive steroids in neuropsychopharmacology
    • Rupprecht R., Holsboer F. Neuroactive steroids in neuropsychopharmacology. Int. Rev. Neurobiol. 2001, 46:461-477.
    • (2001) Int. Rev. Neurobiol. , vol.46 , pp. 461-477
    • Rupprecht, R.1    Holsboer, F.2
  • 59
    • 77952173252 scopus 로고    scopus 로고
    • Steroids-dopamine interactions in the pathophysiology and treatment of CNS disorders
    • Sánchez M.G., Bourque M., Morissette M., Di Paolo T. Steroids-dopamine interactions in the pathophysiology and treatment of CNS disorders. CNS Neurosci. Ther. 2010, 16:e43-e71.
    • (2010) CNS Neurosci. Ther. , vol.16
    • Sánchez, M.G.1    Bourque, M.2    Morissette, M.3    Di Paolo, T.4
  • 61
    • 0034212912 scopus 로고    scopus 로고
    • Toward understanding the biology of a complex phenotype: rat strain and substrain differences in the sensorimotor gating-disruptive effects of dopamine agonists
    • Swerdlow N.R., Martinez Z.A., Hanlon F.M., Platten A., Farid M., Auerbach P., Braff D.L., Geyer M.A. Toward understanding the biology of a complex phenotype: rat strain and substrain differences in the sensorimotor gating-disruptive effects of dopamine agonists. J. Neurosci. 2000, 20:4325-4336.
    • (2000) J. Neurosci. , vol.20 , pp. 4325-4336
    • Swerdlow, N.R.1    Martinez, Z.A.2    Hanlon, F.M.3    Platten, A.4    Farid, M.5    Auerbach, P.6    Braff, D.L.7    Geyer, M.A.8
  • 62
    • 0034927844 scopus 로고    scopus 로고
    • Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges
    • Swerdlow N.R., Geyer M.A., Braff D.L. Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berl.) 2001, 156:194-215.
    • (2001) Psychopharmacology (Berl.) , vol.156 , pp. 194-215
    • Swerdlow, N.R.1    Geyer, M.A.2    Braff, D.L.3
  • 64
    • 0026701781 scopus 로고
    • Four-amino acid segment in steroid 5 alpha-reductase 1 confers sensitivity to finasteride, a competitive inhibitor
    • Thigpen A.E., Russell D.W. Four-amino acid segment in steroid 5 alpha-reductase 1 confers sensitivity to finasteride, a competitive inhibitor. J. Biol. Chem. 1992, 267:8577-8583.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8577-8583
    • Thigpen, A.E.1    Russell, D.W.2
  • 66
    • 0027454169 scopus 로고
    • Intra-accumbens infusion of quinpirole impairs sensorimotor gating of acoustic startle in rats
    • Wan F.J., Swerdlow N.R. Intra-accumbens infusion of quinpirole impairs sensorimotor gating of acoustic startle in rats. Psychopharmacology 1993, 113:103-109.
    • (1993) Psychopharmacology , vol.113 , pp. 103-109
    • Wan, F.J.1    Swerdlow, N.R.2
  • 69
    • 1542563409 scopus 로고    scopus 로고
    • Initial sequencing and comparative analysis of the mouse genome
    • Waterston R.H., Lindblad-Toh K., Birney E., Rogers J., Abril J.F., et al. Initial sequencing and comparative analysis of the mouse genome. Nature 2002, 420:520-562.
    • (2002) Nature , vol.420 , pp. 520-562
    • Waterston, R.H.1    Lindblad-Toh, K.2    Birney, E.3    Rogers, J.4    Abril, J.F.5
  • 71
    • 0033377029 scopus 로고    scopus 로고
    • Neuroactive steroids: their mechanism of action and their function in the stress response
    • Zinder O., Dar D.E. Neuroactive steroids: their mechanism of action and their function in the stress response. Acta Physiol. Scand. 1999, 167:181-188.
    • (1999) Acta Physiol. Scand. , vol.167 , pp. 181-188
    • Zinder, O.1    Dar, D.E.2


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