In situ rat intestine absorption of paclitaxel-loaded solid lipid nanoparticles modified with cell-penetrating peptides

Yaoxue Xuebao

Volumn 48, Issue 1, 2013, Pages 131-137

  Li, Cao Cao ^a   Zhang, Zhen Hai ^b   Zhang, Yin Long ^a   Lü, Hui Xia ^a   Zhou, Jian Ping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Jiangsu Province Academy of Traditional Chinese Medicine   (China)

Author keywords

Cell penetrating peptide; Intestinal absorption; Paclitaxel; Solid lipid nanoparticle

Indexed keywords

PACLITAXEL; SOLID LIPID NANOPARTICLE; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; DRUG ABSORPTION; DUODENUM; INTESTINE PERFUSION; NONHUMAN; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL-PENETRATING PEPTIDES; DRUG CARRIERS; INTESTINAL ABSORPTION; LIPIDS; MALE; NANOPARTICLES; OLIGOPEPTIDES; P-GLYCOPROTEIN; PACLITAXEL; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; STEARIC ACIDS; VERAPAMIL;

EID: 84875046577     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Zuylen LV, Verweij J, Sparreboom A. Role of formulation vehicles in taxane pharmacology [J]. Invest New Drugs, 2001, 19: 125-141. (Pubitemid 32423718)
2. Mo R, Jin X, Li N, et al. The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles [J]. Biomaterials, 2011, 32: 4609-4620.
3. Agueros M, Zabaleta V, Espuelas S, et al. Increased oral bioavailability of paclitaxel by its encapsulation through complex formation with cyclodextrins in poly(anhydride) nanoparticles [J]. J Control Release, 2010, 145: 2-8.
4. Liggins RT, Hunter WL, Burt HM, et al. Solid-state characterization of paclitaxel [J]. J Pham Sci, 1997, 86: 1458-1463.
5. Oostendorp RL, Buckle T, Lambert G, et al. Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice [J]. Invest New Drugs, 2011, 29: 768-776.
6. Malingre MM, Beijnen JH, Schellens JH. Oral delivery of taxanes [J]. Invest New Drugs, 2001, 19: 155-162. (Pubitemid 32423720)
7. Asperen JV, Tellingen OV, Valk MA, et al. Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A [J]. Clin Cancer Res, 1998, 4: 2293-2297. (Pubitemid 28477891)
8. Li R, Eun JS, Lee MK. Pharmacokinetics and biodistribution of paclitaxel loaded in pegylated solid lipid nanoparticles after intravenous administration [J]. Arch Pharm Res, 2011, 34: 331-337.
9. Yuan L. Study of Transport of Solid Lipid Nanoparticles as Oral Drug Carrier in Gastrointestinal Tract [D]. Hangzhou: Zhejiang University, 2008.
10. Liu XL, Zhang WJ, Wei G. Poly (arginine) 8 enhanced intestinal absorption of insulin-loaded nanoparticles [J]. Acta Pharm Sin, 2012, 47: 512-516.
11. Ren J, Qin CG, Xu CL, et al. Development of cell-penetrating peptides as vectors for drug delivery [J]. Acta Pharm Sin, 2010, 45: 17-25.
12. Chen W, Jin MJ, Gao ZG, et al. Preparation and in vitro evaluation of pH-sensitive TAT peptide conjugated micelles [J]. Acta Pharm Sin, 2011, 46: 599-604.
13. Yang PH, Xu H, Zhang QH, et al. Pharmacokinetics of a fusion protein for human acidic fibroblast growth factor and transcriptional activator protein in rat and its penetration across blood-brain barrier [J]. Acta Pharm Sin, 2011, 46: 1204-1208.
14. Zorko M, Langel U. Cell-penetrating peptides: mechanism and kinetics of cargo delivery [J]. Adv Drug Deliv Rev, 2005, 57: 529-545. (Pubitemid 40255559)
15. Nakase I, Konishi Y, Ueda M, et al. Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery [J]. J Control Release, 2012, 159: 181-188.
16. Anko M, Majhenc J, Kogej K, et al. Influence of stearyl and trifluoromethylquinoline modifications of the cell penetrating peptide TP10 on its interaction with a lipid membrane [J]. Biochem Biophys Acta, 2012, 1818: 915-924.
17. Katayama S, Hirose H, Takayama K, et al. Acylation of octaarginine: implication to the use of intracellular delivery vectors [J]. J Control Release, 2011, 149: 29-35.
18. Dubikovskaya EA, Thorne SH, Pillow TH, et al. Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters [J]. Proc Natl Acad Sci USA, 2008, 105: 12128-12133.
19. Zhang YL, Zhang ZH, Jiang TY, et al. Cell uptake of paclitaxel solid lipid nanoparticles modified by cell-penetrating peptides in A549 cells [J]. Pharmazie, 2012, 67: 1-7.
20. Jung T, Kamm W, Breitenbach A, et al. Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake [J]. Eur J Pharm Biopharm, 2000, 50: 147-160. (Pubitemid 30326694)
21. Zhang Y, Zhu HX, Guo LW. Intestinal absorption of berberine alone and in combinations by rats single pass intestinal perfusion in situ [J]. Acta Pharm Sin, 2012, 47: 233-238.
22. Pandita D, Ahuja A, Lather V, et al. Development of lipid-based nanoparticles for enhancing the oral bioavailability of paclitaxel [J]. AAPS PharmSciTech, 2011: 1-11.