메뉴 건너뛰기




Volumn 46, Issue 10, 2011, Pages 1204-1208

Pharmacokinetics of a fusion protein for human acidic fibroblast growth factor and transcriptional activator protein in rat and its penetration across blood-brain barrier

Author keywords

Acidic fibroblast growth factor; Alzheimer's disease; Blood brain barrier; Pharmacokinetics; Transcriptional activator protein

Indexed keywords

FIBROBLAST GROWTH FACTOR 1; HYBRID PROTEIN; TAT HAFGF HYBRID PROTEIN; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 83455258046     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (17)
  • 1
    • 40949161757 scopus 로고    scopus 로고
    • Nerve repair using acidic fibroblast growth factor in human cervical spinal cord injury: A preliminary Phase I clinical study
    • [J]
    • Wu JC, Huang WC, Tsai YA, et al. Nerve repair using acidic fibroblast growth factor in human cervical spinal cord injury: a preliminary Phase I clinical study [J]. J Neurosurg Spine, 2008, 8: 208-214.
    • (2008) J Neurosurg Spine , vol.8 , pp. 208-214
    • Wu, J.C.1    Huang, W.C.2    Tsai, Y.A.3
  • 2
    • 0141742631 scopus 로고    scopus 로고
    • Fibroblast growth factors and their receptors in the central nervous system
    • [J]
    • Reuss B, von Bohlenund Halbach O. Fibroblast growth factors and their receptors in the central nervous system [J]. Cell Tissue Res, 2003, 313: 139-157.
    • (2003) Cell Tissue Res , vol.313 , pp. 139-157
    • Reuss, B.1    Von Bohlenund Halbach, O.2
  • 3
    • 22144432277 scopus 로고    scopus 로고
    • Biological markers of Alzheimer's disease and mild cognitive impairment
    • [J]
    • Maccioni RB, Lavados M, Maccioni CB, et al. Biological markers of Alzheimer's disease and mild cognitive impairment [J]. Curr Alzheimer Res, 2004, 1: 307-314.
    • (2004) Curr Alzheimer Res , vol.1 , pp. 307-314
    • Maccioni, R.B.1    Lavados, M.2    Maccioni, C.B.3
  • 4
    • 78650950140 scopus 로고    scopus 로고
    • TAT-mediated delivery of neuroglobin protects against focal cerebral ischemia in mice
    • [J]
    • Cai B, Lin Y, Xue XH, et al. TAT-mediated delivery of neuroglobin protects against focal cerebral ischemia in mice [J]. Exp Neurol, 2011, 227: 224-231.
    • (2011) Exp Neurol , vol.227 , pp. 224-231
    • Cai, B.1    Lin, Y.2    Xue, X.H.3
  • 6
    • 0036663014 scopus 로고    scopus 로고
    • In vivo delivery of a Bcl-xL fusion protein containing the TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis
    • Cao G, Pei W, Ge H, et al. In vivo delivery of a Bcl-xL fusion protein containing the TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis [J]. J Neurosci, 2002, 22: 5423-5431. (Pubitemid 35386464)
    • (2002) Journal of Neuroscience , vol.22 , Issue.13 , pp. 5423-5431
    • Cao, G.1    Pei, W.2    Ge, H.3    Liang, Q.4    Luo, Y.5    Sharp, F.R.6    Lu, A.7    Ran, R.8    Graham, S.H.9    Chen, J.10
  • 7
    • 0038304351 scopus 로고    scopus 로고
    • Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice
    • DOI 10.1161/01.STR.0000066869.45310.50
    • Kilic U, Kilic E, Dietz G, et al. Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice [J]. Stroke, 2003, 34: 1304-1310. (Pubitemid 36547533)
    • (2003) Stroke , vol.34 , Issue.5 , pp. 1304-1310
    • Kilic, U.1    Kilic, E.2    Dietz, G.P.H.3    Bahr, M.4
  • 8
    • 30444455324 scopus 로고    scopus 로고
    • In vivo delivery of a XIAP (BIR3-RING) fusion protein containing the protein transduction domain protects against neuronal death induced by seizures
    • DOI 10.1016/j.expneurol.2005.08.021, PII S0014488605003043
    • Li T, Fan Y, Luo Y, et al. In vivo delivery of a XIAP (BIR3-RING) fusion protein containing the protein transduction domain protects against neuronal death induced by seizures [J]. Exp Neurol, 2006, 197: 301-308. (Pubitemid 43077137)
    • (2006) Experimental Neurology , vol.197 , Issue.2 , pp. 301-308
    • Li, T.1    Fan, Y.2    Luo, Y.3    Xiao, B.4    Lu, C.5
  • 10
    • 84878391548 scopus 로고    scopus 로고
    • Expression, purification and bioassay of Tat-aFGF fusion protein in Escherichia coli
    • [J]
    • Lin JC, Zhang MJ, Su ZJ, et al. Expression, purification and bioassay of Tat-aFGF fusion protein in Escherichia coli [J]. China Biotechnol, 2010, 30: 11-17.
    • (2010) China Biotechnol , vol.30 , pp. 11-17
    • Lin, J.C.1    Zhang, M.J.2    Su, Z.J.3
  • 11
    • 77950625113 scopus 로고    scopus 로고
    • Development of cell-penetrating peptides as vectors for drug delivery
    • [J]
    • Ren J, Qin CG, Xu CL, et al. Development of cell-penetrating peptides as vectors for drug delivery [J]. Acta Pharm Sin, 2010, 45: 17-25.
    • (2010) Acta Pharm Sin , vol.45 , pp. 17-25
    • Ren, J.1    Qin, C.G.2    Xu, C.L.3
  • 12
    • 83455201955 scopus 로고    scopus 로고
    • The methodology and experimental design in pharmacokinetics study of biotechnological drugs
    • [J]
    • Wang XF, Zheng Q. The methodology and experimental design in pharmacokinetics study of biotechnological drugs [J]. China Biotechnol, 2004, 24: 80-83.
    • (2004) China Biotechnol , vol.24 , pp. 80-83
    • Wang, X.F.1    Zheng, Q.2
  • 14
    • 0034595111 scopus 로고    scopus 로고
    • 1H NMR structural characterization of a nonmitogenic, vasodilatory, ischemia-protector and neuromodulatory acidic fibroblast growth factor
    • [J]
    • 1H NMR structural characterization of a nonmitogenic, vasodilatory, ischemia-protector and neuromodulatory acidic fibroblast growth factor [J]. Biochemistry, 2000, 39: 4982-4993.
    • (2000) Biochemistry , vol.39 , pp. 4982-4993
    • Lozano, R.M.1    Pineda-Lucena, A.2    Gonzalez, C.3
  • 15
    • 33745009995 scopus 로고    scopus 로고
    • A novel therapeutic approach to 6-OHDA-induced Parkinson's disease in rats via supplementation of PTD-conjugated tyrosine hydroxylase
    • DOI 10.1016/j.bbrc.2006.03.247, PII S0006291X06007261
    • Wu SP, Fu AL, Wang YX, et al. A novel therapeutic approach to 6-OHDA-induced Parkinson's disease in rats via supplementation of PTD-conjugated tyrosine hydroxylase [J]. Biochem Biophys Res Commun, 2006, 346: 1-6. (Pubitemid 43865960)
    • (2006) Biochemical and Biophysical Research Communications , vol.346 , Issue.1 , pp. 1-6
    • Wu, S.P.1    Fu, A.L.2    Wang, Y.X.3    Yu, L.P.4    Jia, P.Y.5    Li, Q.6    Jin, G.Z.7    Sun, M.J.8
  • 16
    • 0642337937 scopus 로고    scopus 로고
    • Pharmacokinetic study of recombinant human acidic fibroblast growth factor in rabbits by skin external use
    • [J]
    • Li XK, Xu H, Zhao W, et al. Pharmacokinetic study of recombinant human acidic fibroblast growth factor in rabbits by skin external use [J]. Acta Pharm Sin, 2002, 37: 424-427.
    • (2002) Acta Pharm Sin , vol.37 , pp. 424-427
    • Li, X.K.1    Xu, H.2    Zhao, W.3
  • 17
    • 34250835903 scopus 로고    scopus 로고
    • A comprehensive model for the cellular uptake of cationic cell-penetrating peptides
    • DOI 10.1111/j.1600-0854.2007.00572.x
    • Duchardt F, Fotin-Mleczek M, Schwarz H, et al. A comprehensive model for the cellular uptake of cationic cell-penetrating peptides [J]. Traffic, 2007, 8: 848-866. (Pubitemid 46971632)
    • (2007) Traffic , vol.8 , Issue.7 , pp. 848-866
    • Duchardt, F.1    Fotin-Mleczek, M.2    Schwarz, H.3    Fischer, R.4    Brock, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.