Poly(arginine)8 enhanced intestinal absorption of insulin-loaded nanoparticles

Yaoxue Xuebao

Volumn 47, Issue 4, 2012, Pages 512-516

  Liu, Xiao Li ^a   Zhang, Wen Jian ^a   Wei, Gang ^a   Lu, Wei Yue ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Cell penetrating peptide; Insulin; Intestinal absorption; Nanoparticle; Poly(lactic co glycolic acid)

Indexed keywords

GLUCOSE; INSULIN; MACROGOL; NANOPARTICLE; POLYARGININE; POLYGLACTIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; FEASIBILITY STUDY; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; INTESTINE LOOP; NONHUMAN; PHARMACODYNAMICS; PHYSICOCHEMICAL MODEL; RADIOIMMUNOASSAY; RAT; SLOW RELEASE FORMULATION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; BLOOD GLUCOSE; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HYPOGLYCEMIC AGENTS; INSULIN; INTESTINAL ABSORPTION; LACTIC ACID; MALE; NANOPARTICLES; PARTICLE SIZE; PEPTIDES; POLYGLYCOLIC ACID; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84862221693     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Zheng CH, Liang WQ, Yu HY. Preparation of alginate-chitosan-poly (lactic-co-glycolic acid) composite microsphere and its regulation of protein release [J]. Acta Pharm Sin 2005, 40: 182-186. (Pubitemid 40445199)
2. Sarmento B, Martins S, Ferreira D, et al. Oral insulin delivery by means of solid lipid nanoparticles [J]. Int J Nanomed, 2007, 2: 743-749.
3. Chien YW, Banga AK. Potential developments in systemic delivery of insulin [J]. Drug Dev Ind Pharm, 1989, 15: 1601-1634. (Pubitemid 19202999)
4. Reis CP, Veiga FJ, Ribeiro AJ, et al. Nanoparticulate biopolymers deliver insulin orally eliciting pharmacological response [J]. J Pharm Sci, 2008, 97: 5290-5305.
5. Morris MC, Depollier J, Mery J, et al. A peptide carrier for the delivery of biologically active proteins into mammalian cells[J]. Nat Biotechnol, 2001, 19: 1173-1176. (Pubitemid 33115705)
6. Plapied L, Duhem N, Rieux AD, et al. Fate of polymeric nanocarriers for oral drug delivery [J]. Curr Opin Colloid Interface Sci, 2011, 16: 228-237.
7. Russell-Jones GJ. The potential use of receptor-mediated endocytosis for oral drug delivery [J]. Adv Drug Deliv Rev, 2001, 46: 59-73.
8. Ren J, Qin CG, Xu CL, et al. Development of cell-penetrating peptides as vectors for drug delivery [J]. Acta Pharm Sin 2010, 45: 17-25.
9. Argyrisa EG, Kulkoskya J, Meyerb ME, et al. The perlecan heparan sulfate proteoglycan mediates cellular uptake of HIV-1 Tat through a pathway responsible for biological activity [J]. Virology, 2004, 330: 481-486.
10. Brooks H, Lebleu B, Vivès E. Tat peptide-mediated cellular delivery: back to basics [J]. Adv Drug Deliv Rev, 2005, 57: 559-577. (Pubitemid 40255561)
11. Schmidt N, Mishra A, Lai GH, et al. Arginine-rich cell-penetrating peptides [J]. FEBS Lett, 2010, 584: 1806-1813.
12. Trabulo S, Cardoso AL, Mano M, et al. Cell-penetrating peptides - mechanisms of cellular uptake and generation of delivery systems [J]. Pharmaceuticals, 2010, 3: 961-993.
13. Oh E, Delehanty JB, Sapsford KE, et al. Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size [J]. ACS Nano, 2011, 5: 6434-6448.
14. Furuhata M, Kawakami H, Toma K, et al. Intracellular delivery of proteins in complexes with oligoarginine-modified liposomes and the effect of oligoarginine length [J]. Bioconjug Chem, 2006, 17: 935-942. (Pubitemid 44162611)
15. Lee JS, Tung CH. Lipo-oligoarginines as effective delivery vectors to promote cellular uptake [J]. Mol Biosyst, 2010, 6: 2049-2055.
16. Morishita M, Kamei N, Ehara J, et al. A novel approach using functional peptides for efficient intestinal absorption of insulin [J]. J Control Release, 2007, 118: 177-184. (Pubitemid 46329737)
17. Kamei N, Morishita M, Eda Y, et al. Usefulness of cell-penetrating peptides to improve intestinal insulin absorption [J]. J Control Release, 2008, 132: 21-25.
18. Kamei N, Morishita M, Takayama K. Importance of intermolecular interaction on the improvement of intestinal therapeutic peptide/protein absorption using cell-penetrating peptides [J]. J Control Release, 2009, 136: 179-186.