Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages

Angiogenesis

Volumn 15, Issue 4, 2012, Pages 609-622

  Camelo, Serge ^a   Raoul, William ^b,c   Lavalette, Sophie ^b,c   Calippe, Bertrand ^b,c   Cristofaro, Brunella ^a   Levy, Olivier ^b,c   Houssier, Marianne ^a   Sulpice, Eric ^a   Jonet, Laurent ^a   Klein, Christophe ^a   Devevre, Estelle ^a   Thuret, Gilles ^b   Duarte, Antonio ^b,c   Eichmann, Anne ^a   Leconte, Laurence ^d   Guillonneau, Xavier ^b,c   Sennlaub, Florian ^b,c  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b INSTITUT DE LA VISION   (France)

^c CNRS   (France)

^d INSERM UMRS 968 ^*

Author keywords

Age related macular degeneration; Angiogenesis; DLL4; Eye; Macrophages; Notch

Indexed keywords

INTERLEUKIN 1BETA; NOTCH1 RECEPTOR; NOTCH4 RECEPTOR; RECOMBINANT DELTA LIKE 4 PROTEIN; RECOMBINANT PROTEIN; SERINE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; GENE INDUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUBRETINAL NEOVASCULARIZATION; VASCULAR ENDOTHELIUM; VASCULAR RING;

EID: 84875035470     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-012-9290-0     Document Type: Article

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