Determinants of sequence-specific DNA methylation: Target recognition and catalysis are coupled in M.HhaI

Biochemistry

Volumn 45, Issue 51, 2006, Pages 15563-15572

  Youngblood, Ben ^a   Buller, Fabian ^a,b   Reich, Norbert O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; DNA; MUTAGENESIS; PROTEINS;

COCRYSTAL STRUCTURE; CONFORMATIONAL TRANSITIONS; METHYLATION; WILD TYPE ENZYMES;

ALKYLATION;

BACTERIAL DNA; DNA METHYLTRANSFERASE;

AMINO ACID SUBSTITUTION; ANISOTROPY; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DNA METHYLATION; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SPECIFICITY; FLUORESCENCE POLARIZATION; GEL MOBILITY SHIFT ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; STEADY STATE; STEREOCHEMISTRY; THERMODYNAMICS; WILD TYPE;

AMINO ACID SUBSTITUTION; BASE SEQUENCE; BINDING SITES; CATALYSIS; CONSERVED SEQUENCE; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; ESCHERICHIA COLI; KINETICS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SITE-SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE-SPECIFIC); SUBSTRATE SPECIFICITY; THERMODYNAMICS;

BACTERIA (MICROORGANISMS);

EID: 33845921607     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061414t     Document Type: Article

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