Long-range structural and dynamical changes induced by cofactor binding in DNA methyltransferase M.HhaI

Biochemistry

Volumn 46, Issue 24, 2007, Pages 7261-7268

  Zhou, Hongjun ^a   Shatz, Whitney ^a   Purdy, Matthew M ^a   Fera, Nick ^a   Dahlquist, Frederick W ^a   Reich, Norbert O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC PROPERTIES; COFACTORS; LIGAND BINDING; METHYLTRANSFERASE;

BACTERIA; BINDING SITES; CONFORMATIONS; DNA; LIGANDS; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PROTEINS;

ENZYME KINETICS;

CYTOSINE; DNA METHYLTRANSFERASE; PROTEIN M.HHAI; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; DNA MODIFICATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN SECONDARY STRUCTURE;

ALLOSTERIC REGULATION; BACTERIAL PROTEINS; BASE SEQUENCE; COENZYMES; DNA PRIMERS; LIGANDS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; S-ADENOSYLHOMOCYSTEINE; SITE-SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE-SPECIFIC); SUBSTRATE SPECIFICITY; THERMODYNAMICS;

BACTERIA (MICROORGANISMS);

EID: 34250839422     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi602662e     Document Type: Article

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