Probenecid, a gout remedy, inhibits pannexin 1 channels

American Journal of Physiology - Cell Physiology

Volumn 295, Issue 3, 2008, Pages

  Silverman, William ^a   Locovei, Silviu ^a   Dahl, Gerhard ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

ATP release; Connexin; Erythrocyte; Transport

Indexed keywords

ADENOSINE TRIPHOSPHATE; GAP JUNCTION PROTEIN; ORGANIC ANION TRANSPORTER; PANNEXIN 1 CHANNEL; PROBENECID; UNCLASSIFIED DRUG; URATE; URIC ACID; 5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; 5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID; ANTIGOUT AGENT; CONNEXIN 32; CONNEXIN 46; ION CHANNEL; NITROBENZOIC ACID DERIVATIVE;

ARTICLE; CONCENTRATION (PARAMETERS); DRUG EXCRETION; DRUG INHIBITION; DRUG MECHANISM; DRUG TRANSPORT; GOUT; MEMBRANE CHANNEL; NONHUMAN; PRIORITY JOURNAL; URIC ACID URINE LEVEL; ANIMAL; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG ANTAGONISM; GENETICS; METABOLISM; OOCYTE; XENOPUS LAEVIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CONNEXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GOUT SUPPRESSANTS; ION CHANNELS; MEMBRANE POTENTIALS; NITROBENZOATES; OOCYTES; PROBENECID; XENOPUS LAEVIS;

EID: 53449101616     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00227.2008     Document Type: Article

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