Designing CAF-adjuvanted dry powder vaccines: Spray drying preserves the adjuvant activity of CAF01

Journal of Controlled Release

Volumn 167, Issue 3, 2013, Pages 256-264

  Ingvarsson, Pall Thor ^a   Schmidt, Signe Tandrup ^a   Christensen, Dennis ^b   Larsen, Niels Bent ^c   Hinrichs, Wouter Leonardus Joseph ^d   Andersen, Peter ^b   Rantanen, Jukka ^a   Nielsen, Hanne Mørck ^a   Yang, Mingshi ^a   Foged, Camilla ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b STATENS SERUM INSTITUT   (Denmark)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^d UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Adjuvants; CAF01; Liposomes; Spray drying; Vaccines

Indexed keywords

ADJUVANTS; CAF01; LIPID ACCUMULATIONS; LIQUID FORMULATIONS; NANOCOMPOSITE MICROPARTICLES; PARTICLE ENGINEERING; PROCESSING CONDITION; SPRAY-DRIED POWDERS;

DIGITAL STORAGE; GLASS; LIPOSOMES; OPTIMIZATION; PHASE SEPARATION; POLYOLS; STABILIZATION; SUGARS; VACCINES;

SPRAY DRYING;

BCG VACCINE; DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; LACTOSE; LIPOSOME; MANNITOL; TREHALOSE; TREHALOSE 6,6' DIBEHENATE; UNCLASSIFIED DRUG;

AEROSOL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG FORMULATION; DRUG STABILITY; DRY POWDER; FEMALE; IMMUNIZATION; IN VIVO STUDY; LIPID STORAGE; MOUSE; NONHUMAN; PARTICLE SIZE; PHASE SEPARATION; PRIORITY JOURNAL; SPRAY DRYING;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CATIONS; DESICCATION; DRUG COMPOUNDING; FEMALE; GLYCOLIPIDS; LACTOSE; LIPOSOMES; MANNITOL; MICE; MICE, INBRED C57BL; POWDERS; QUATERNARY AMMONIUM COMPOUNDS; RECOMBINANT FUSION PROTEINS; TREHALOSE; VACCINES;

EID: 84874931392     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.01.031     Document Type: Article

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