Anti-neuroinflammatory properties of synthetic cryptolepine in human neuroblastoma cells: Possible involvement of NF-κB and p38 MAPK inhibition

European Journal of Medicinal Chemistry

Volumn 63, Issue , 2013, Pages 333-339

  Olajide, Olumayokun A ^a,b   Bhatia, Harsharan S ^b   De Oliveira, Antonio C P ^b,c   Wright, Colin W ^d   Fiebich, Bernd L ^b,e  

^a UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

^b UNIVERSITY OF FREIBURG   (Germany)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^d UNIVERSITY OF BRADFORD   (United Kingdom)

^e VIVACELL BIOTECHNOLOGY GMBH   (Germany)

Author keywords

Cryptolepine; Cryptolepis sanguinolenta; Cyclooxygenase 2; Neuroinflammation; NF B; p38 MAPK

Indexed keywords

CRYPTOLEPINE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN SYNTHASE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CRYPTOLEPIS SANGUINOLENTA; CULTURE MEDIUM; DOSE RESPONSE; GENE EXPRESSION; HERB; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MICROSOME; NERVE CELL CULTURE; NERVOUS SYSTEM INFLAMMATION; NEUROBLASTOMA; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANTI-INFLAMMATORY AGENTS; CELL LINE, TUMOR; CRYPTOLEPIS; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IMMUNOBLOTTING; INDOLE ALKALOIDS; INTERLEUKIN-1BETA; INTRAMOLECULAR OXIDOREDUCTASES; MOLECULAR STRUCTURE; NEUROBLASTOMA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLANT EXTRACTS; QUINOLINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA;

EID: 84874929719     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.02.004     Document Type: Article

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