메뉴 건너뛰기




Volumn 5, Issue 3, 2012, Pages 225-230

Receptor-mediated oxidative stress in murine cerebellar neurons is accompanied by phosphorylation of MAP (ERK 1/2) kinase

Author keywords

Carnosine; ERK 1 2; Homocysteine; Na K ATPase; Neurons; NMDA; Ouabain; Oxidative stress

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CARNOSINE; DIZOCILPINE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; HOMOCYSTEINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OUABAIN; REACTIVE OXYGEN METABOLITE;

EID: 84874924907     PISSN: 18746098     EISSN: 18746128     Source Type: Journal    
DOI: 10.2174/1874609811205030009     Document Type: Article
Times cited : (18)

References (42)
  • 1
    • 0029945349 scopus 로고    scopus 로고
    • Mitogenactivated protein kinase (MAPK) activation by butylated hydroxytoluene hydroperoxide: Implications for cellular survival and tumor promotion
    • Guyton KZ, Gorospe M, Kensler TW, Holbrook NJ. Mitogenactivated protein kinase (MAPK) activation by butylated hydroxytoluene hydroperoxide: implications for cellular survival and tumor promotion. Cancer Res 1996 1; 56(15): 3480-5.
    • (1996) Cancer Res , vol.56 , Issue.15 , pp. 3480-3485
    • Guyton, K.Z.1    Gorospe, M.2    Kensler, T.W.3    Holbrook, N.J.4
  • 3
    • 75149186051 scopus 로고    scopus 로고
    • Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form
    • Klafki HW, Lewczuk P, Kamrowski-Kruck H, et al. Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form. J Alzheimer's Dis 2009; 18(3): 613-22.
    • (2009) J Alzheimer's Dis , vol.18 , Issue.3 , pp. 613-622
    • Klafki, H.W.1    Lewczuk, P.2    Kamrowski-Kruck, H.3
  • 4
    • 0036770144 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase pathways in Alzheimer's disease
    • Zhu X, Lee HG, Raina AK, Perry G, Smith MA. The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals 2002; 11(5): 270-81.
    • (2002) Neurosignals , vol.11 , Issue.5 , pp. 270-281
    • Zhu, X.1    Lee, H.G.2    Raina, A.K.3    Perry, G.4    Smith, M.A.5
  • 5
    • 76749088358 scopus 로고    scopus 로고
    • Pathological roles of MAPK signaling pathways in human diseases
    • Kim EK, Choi EJ. Pathological roles of MAPK signaling pathways in human diseases. Biochim Biophys Acta 2010; 1802(4): 396-05.
    • (2010) Biochim Biophys Acta , vol.1802 , Issue.4 , pp. 396-405
    • Kim, E.K.1    Choi, E.J.2
  • 9
    • 0028356548 scopus 로고
    • Synaptic plasticity: LTP and LTD
    • Bear MF, Malenka RC. Synaptic plasticity: LTP and LTD. Curr Opin Neurobiol 1994; 4(3): 389-99.
    • (1994) Curr Opin Neurobiol , vol.4 , Issue.3 , pp. 389-399
    • Bear, M.F.1    Malenka, R.C.2
  • 10
    • 0027993134 scopus 로고
    • Inhibitory effects of dihydropyridines on macroscopic K currents and on the largeconductance Ca-activated K-channel in cultured cerebellar granule cells
    • Fagni L, Bossu JL, Bockaert J. Inhibitory effects of dihydropyridines on macroscopic K currents and on the largeconductance Ca-activated K-channel in cultured cerebellar granule cells. Pflugers Arch 1994; 429(2): 176-82.
    • (1994) Pflugers Arch , vol.429 , Issue.2 , pp. 176-182
    • Fagni, L.1    Bossu, J.L.2    Bockaert, J.3
  • 11
    • 0028856368 scopus 로고
    • NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: Implication for cell death
    • Gunasekar PG, Kanthasamy AG, Borowitz JL, Isom GE. NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death. J Neurochem 1995; 65(5): 2016-21.
    • (1995) J Neurochem , vol.65 , Issue.5 , pp. 2016-2221
    • Gunasekar, P.G.1    Kanthasamy, A.G.2    Borowitz, J.L.3    Isom, G.E.4
  • 12
    • 0035283075 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptormediated mitochondrial Ca overload in acute excitotoxic motor neuron death: A mechanism distinct from chronic neurotoxicity after Ca influx
    • Urushitani M, Nakamizo T, Inoue R, Sawada H, Kihara T, Honda K, Akaike A, Shimohama S. N-methyl-D-aspartate receptormediated mitochondrial Ca overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca influx. J Neurosci Res 2001; 63(5): 377-87.
    • (2001) J Neurosci Res , vol.63 , Issue.5 , pp. 377-387
    • Urushitani, M.1    Nakamizo, T.2    Inoue, R.3    Sawada, H.4    Kihara, T.5    Honda, K.6    Akaike, A.7    Shimohama, S.8
  • 13
    • 34248549227 scopus 로고    scopus 로고
    • Calcium, iron and neuronal function
    • Hidalgo C, Núñez MT. Calcium, iron and neuronal function. IUBMB Life 2007 (4-5): 280-5.
    • (2007) IUBMB Life , Issue.4-5 , pp. 280-285
    • Hidalgo, C.1    Núñez, M.T.2
  • 14
    • 33750290419 scopus 로고    scopus 로고
    • Triggering endogenous neuroprotective mechanisms in Parkinson's disease: Studies with a cellular model
    • Zigmond MJ. Triggering endogenous neuroprotective mechanisms in Parkinson's disease: studies with a cellular model. J Neural Transm Suppl. 2006; (70): 439-42.
    • (2006) J Neural Transm , vol.70 , Issue.SUPPL. , pp. 439-442
    • Zigmond, M.J.1
  • 15
    • 67650077224 scopus 로고    scopus 로고
    • Molecular mechanisms of homocysteine toxicity
    • Boldyrev AA. Molecular mechanisms of homocysteine toxicity. Biochemistry (Moscow) 2009; 74(6): 589-98.
    • (2009) Biochemistry (Moscow) , vol.74 , Issue.6 , pp. 589-598
    • Boldyrev, A.A.1
  • 16
    • 34447310517 scopus 로고    scopus 로고
    • Effects of Homocysteine and Homocysteinic Acid on cerebellar granule cells
    • Makhro V, Bulygina ER, Boldyrev AA. Effects of Homocysteine and Homocysteinic Acid on cerebellar granule cells. Neurochem J 2007; 1(2): 127-32.
    • (2007) Neurochem J , vol.1 , Issue.2 , pp. 127-132
    • Makhro, V.1    Bulygina, E.R.2    Boldyrev, A.A.3
  • 17
    • 0030604041 scopus 로고    scopus 로고
    • Involvement of N-methyl-D-aspartate receptor and free radical in homocysteine-mediated toxicity on rat cerebellar granule cells in culture
    • Kim WK, Pae YS. Involvement of N-methyl-D-aspartate receptor and free radical in homocysteine-mediated toxicity on rat cerebellar granule cells in culture. Neurosci Lett 1996; 216(2): 117-20.
    • (1996) Neurosci Lett , vol.216 , Issue.2 , pp. 117-120
    • Kim, W.K.1    Pae, Y.S.2
  • 18
    • 34547742032 scopus 로고    scopus 로고
    • Why Homocysteine Is a Risk Factor of Neurodegenerative Diseases
    • Boldyrev AA. Why Homocysteine Is a Risk Factor of Neurodegenerative Diseases. Neurochem J 2007; 1(1): 14-20.
    • (2007) Neurochem J , vol.1 , Issue.1 , pp. 14-20
    • Boldyrev, A.A.1
  • 19
    • 0000720899 scopus 로고
    • Structure and mechanism of the Na/K-ATPase
    • Cantley LC. Structure and mechanism of the Na/K-ATPase. Curr Top Bioenerg 1981; 2: 201-37.
    • (1981) Curr Top Bioenerg , vol.2 , pp. 201-237
    • Cantley, L.C.1
  • 20
    • 0032496727 scopus 로고    scopus 로고
    • Different effects of low and high dose cardiotonic steroids on cytosolic calcium in spontaneously active hippocampal neurons and incultured glia
    • Monteith GR, Blaustein MP. Different effects of low and high dose cardiotonic steroids on cytosolic calcium in spontaneously active hippocampal neurons and incultured glia. Brain Res 1998; 795(1-2):325-40.
    • (1998) Brain Res , vol.795 , Issue.1-2 , pp. 325-340
    • Monteith, G.R.1    Blaustein, M.P.2
  • 21
    • 0032511095 scopus 로고    scopus 로고
    • Multiple signal transduction pathways link Na/K-ATPase to growth-related genes in cardiac myocytes
    • Kometiani P, Li J, Gnudi L, Kahn BB, Askari A, Xie Z. Multiple signal transduction pathways link Na/K-ATPase to growth-related genes in cardiac myocytes. J Biol Chem 1998; 273: 15249-56.
    • (1998) J Biol Chem , vol.273 , pp. 15249-15556
    • Kometiani, P.1    Li, J.2    Gnudi, L.3    Kahn, B.B.4    Askari, A.5    Xie, Z.6
  • 22
    • 0036098774 scopus 로고    scopus 로고
    • Na/K-ATPase as a signal transducer
    • Xie Z, Askari A. Na/K-ATPase as a signal transducer. Eur J Biochem 2002; 269: 2434-39.
    • (2002) Eur J Biochem , vol.269 , pp. 2434-2439
    • Xie, Z.1    Askari, A.2
  • 23
    • 4344587222 scopus 로고    scopus 로고
    • Glutamate Receptors Communicate with Na/K-ATPase in Rat Cerebellum Granule Cells
    • Boldyrev AA, Bulygina ER, Carpenter D, Schoner W. Glutamate Receptors Communicate with Na/K-ATPase in Rat Cerebellum Granule Cells. J Molecular Neurosci 2003; 3(21): 213-22.
    • (2003) J Molecular Neurosci , vol.3 , Issue.21 , pp. 213-222
    • Boldyrev, A.A.1    Bulygina, E.R.2    Carpenter, D.3    Schoner, W.4
  • 24
    • 48749107906 scopus 로고    scopus 로고
    • Both Ouabain-Sensitive and Ouabain-Resistant Isoforms of Na/KATPase in Cerebellar Granule Cells Control MAP Kinase Activity
    • Karpova LV, Akkuratov EE, Bulygina ER, Boldyrev AA. Both Ouabain-Sensitive and Ouabain-Resistant Isoforms of Na/KATPase in Cerebellar Granule Cells Control MAP Kinase Activity. Membr Cell Biol 2008; 2(2): 156-60.
    • (2008) Membr Cell Biol , vol.2 , Issue.2 , pp. 156-160
    • Karpova, L.V.1    Akkuratov, E.E.2    Bulygina, E.R.3    Boldyrev, A.A.4
  • 25
    • 63849168850 scopus 로고    scopus 로고
    • Endogenous cardiotonic steroids: Physiology, pharmacology, and novel therapeutic targets
    • Bagrov AY, Shapiro JI, Fedorova OV. Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets. Pharmacol Rev 2009; 61(1): 9-38.
    • (2009) Pharmacol Rev , vol.61 , Issue.1 , pp. 9-38
    • Bagrov, A.Y.1    Shapiro, J.I.2    Fedorova, O.V.3
  • 26
    • 0036916554 scopus 로고    scopus 로고
    • Reduction of Na/K-ATPase activity in hippocampus of rats subjected to chemically induced hyperhomocysteinemia
    • Streck EL, Matte C, Vieira PS, Rombaldi F, Wannmacher CM, Wajner M, Wyse AT. Reduction of Na/K-ATPase activity in hippocampus of rats subjected to chemically induced hyperhomocysteinemia. Neurochem Res 2002; 27(12): 1593-98.
    • (2002) Neurochem Res , vol.27 , Issue.12 , pp. 1593-1598
    • Streck, E.L.1    Matte, C.2    Vieira, P.S.3    Rombaldi, F.4    Wannmacher, C.M.5    Wajner, M.6    Wyse, A.T.7
  • 27
    • 36949018704 scopus 로고    scopus 로고
    • The expression of NMDA receptor subunits in cerebral cortex and hippocampus is differentially increased by administration of endobain E, a Na/KATPase inhibitor
    • Bersier MG, Pena C, de Lores Arnaiz RG. The expression of NMDA receptor subunits in cerebral cortex and hippocampus is differentially increased by administration of endobain E, a Na/KATPase inhibitor. Neurochem Res 2008; 33(1): 66-72.
    • (2008) Neurochem Res , vol.33 , Issue.1 , pp. 66-72
    • Bersier, M.G.1    Pena, C.2    de Lores, A.R.G.3
  • 28
    • 84885859622 scopus 로고    scopus 로고
    • Demonstration of differences in the action of several metabotropic and ionotropic glutamate agonists on intracellular reactive oxygen species and the Na-pump
    • Bulygina ER, Boldyrev AA. Demonstration of differences in the action of several metabotropic and ionotropic glutamate agonists on intracellular reactive oxygen species and the Na-pump. J Alzheimer's Disease 2004; 5: 6.
    • (2004) J Alzheimer's Disease , vol.5 , pp. 6
    • Bulygina, E.R.1    Boldyrev, A.A.2
  • 29
    • 0036757544 scopus 로고    scopus 로고
    • Activation of glutamate receptors inhibits Na/K-ATPase of cerebellum granule cells
    • Bulygina ER, Lyapina LY, Boldyrev AA. Activation of glutamate receptors inhibits Na/K-ATPase of cerebellum granule cells. Biochem 2002; 67(9): 1001-5.
    • (2002) Biochem , vol.67 , Issue.9 , pp. 1001-1005
    • Bulygina, E.R.1    Lyapina, L.Y.2    Boldyrev, A.A.3
  • 30
    • 0026920529 scopus 로고
    • Carnosine: Biological role and prospects for use in medicine
    • Boldyrev AA. Carnosine: biological role and prospects for use in medicine. Biochem 1992; 57(9): 1302-10.
    • (1992) Biochem , vol.57 , Issue.9 , pp. 1302-1310
    • Boldyrev, A.A.1
  • 31
    • 0025081749 scopus 로고
    • The histidine-containing dipeptides, carnosine and anserine: Distribution, properties and biological significance
    • Boldyrev AA, Severin SE. The histidine-containing dipeptides, carnosine and anserine: distribution, properties and biological significance. Adv Enzyme Regul 1990; 30: 175-94.
    • (1990) Adv Enzyme Regul , vol.30 , pp. 175-194
    • Boldyrev, A.A.1    Severin, S.E.2
  • 32
    • 0029583470 scopus 로고
    • Lipopolysaccharide induces manganese superoxide dismutase in the rat pancreas: Its role in caerulein pancreatitis
    • Abe R, Shimoseqawa T, Moriizumi S, et al. Lipopolysaccharide induces manganese superoxide dismutase in the rat pancreas: its role in caerulein pancreatitis. Biochem Biophys Res Commun 1995; 217(3): 1216-22.
    • (1995) Biochem Biophys Res Commun , vol.217 , Issue.3 , pp. 1216-1222
    • Abe, R.1    Shimoseqawa, T.2    Moriizumi, S.3
  • 33
    • 0033605527 scopus 로고    scopus 로고
    • Carnosine and taurine protect rat cerebellar granular cells from free radical damage
    • Boldyrev AA, Johnson P, Wei Y, Tan Y, Carpenter DO. Carnosine and taurine protect rat cerebellar granular cells from free radical damage. Neurosci Lett 1999; 263(2-3):169-72.
    • (1999) Neurosci Lett , vol.263 , Issue.2-3 , pp. 169-172
    • Boldyrev, A.A.1    Johnson, P.2    Wei, Y.3    Tan, Y.4    Carpenter, D.O.5
  • 34
    • 77952395404 scopus 로고    scopus 로고
    • Carnosine as a natural antioxidant and geroprotector: From molecular mechanisms to clinical trials
    • Boldyrev AA, Stvolinsky SL, Fedorova TN, Suslina ZA. Carnosine as a natural antioxidant and geroprotector: from molecular mechanisms to clinical trials. Rejuv Res 2010; 13(2-3): 156-58.
    • (2010) Rejuv Res , vol.13 , Issue.2-3 , pp. 156-158
    • Boldyrev, A.A.1    Stvolinsky, S.L.2    Fedorova, T.N.3    Suslina, Z.A.4
  • 35
  • 36
    • 18744374615 scopus 로고    scopus 로고
    • Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
    • Perry G, Nunomura A, Hirai K, et al. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med 2002; 33(11): 1475-9.
    • (2002) Free Radic Biol Med , vol.33 , Issue.11 , pp. 1475-1479
    • Perry, G.1    Nunomura, A.2    Hirai, K.3
  • 37
    • 15844421283 scopus 로고    scopus 로고
    • Glutamate receptors modulate oxidative stress in neuronal cells
    • Boldyrev A, Bulygina E, Makhro A. Glutamate receptors modulate oxidative stress in neuronal cells. Neurotox Res 2004; 6(7-8): 581-7.
    • (2004) Neurotox Res , vol.6 , Issue.7-8 , pp. 581-587
    • Boldyrev, A.1    Bulygina, E.2    Makhro, A.3
  • 38
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 1995; 80(2): 179-85.
    • (1995) Cell , vol.80 , Issue.2 , pp. 179-185
    • Marshall, C.J.1
  • 39
    • 67650484107 scopus 로고    scopus 로고
    • Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death
    • Poddar R, Paul S. Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death. J Neurochem 2009; 110(3): 1095-06.
    • (2009) J Neurochem , vol.110 , Issue.3 , pp. 1095-1096
    • Poddar, R.1    Paul, S.2
  • 40
    • 0029925683 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by neurotrophic factors
    • Segal RA, Greenberg ME. Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci 1996; 19: 463-89.
    • (1996) Annu Rev Neurosci , vol.19 , pp. 463-489
    • Segal, R.A.1    Greenberg, M.E.2
  • 41
    • 33750584426 scopus 로고    scopus 로고
    • Sustained versus transient ERK1/2 signaling underlies the anti- and proapoptotic effects of oxidative stress in human RPE cells
    • Glotin AL, Calipel A, Brossas JY, Faussat AM, Treton J, Mascarelli F. Sustained versus transient ERK1/2 signaling underlies the anti- and proapoptotic effects of oxidative stress in human RPE cells. Invest Ophthalmol Vis Sci 2006; 47(10): 4614-23.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , Issue.10 , pp. 4614-4623
    • Glotin, A.L.1    Calipel, A.2    Brossas, J.Y.3    Faussat, A.M.4    Treton, J.5    Mascarelli, F.6
  • 42
    • 77249120095 scopus 로고    scopus 로고
    • Different neuronal Na/K-ATPase isoforms are involved in diverse signaling pathways
    • Karpova LV, Bulygina ER, Boldyrev AA. Different neuronal Na/K-ATPase isoforms are involved in diverse signaling pathways. Cell Biochem Funct 2010; 28(2): 135-41.
    • (2010) Cell Biochem Funct , vol.28 , Issue.2 , pp. 135-141
    • Karpova, L.V.1    Bulygina, E.R.2    Boldyrev, A.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.