Different effects of low and high dose cardiotonic steroids on cytosolic calcium in spontaneously active hippocampal neurons and in co-cultured glia

Brain Research

Volumn 795, Issue 1-2, 1998, Pages 325-340

  Monteith, Gregory R ^a,b   Blaustein, Mordecai P ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Glia; Na+ pump; Neurons; Ouabain

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); DIHYDROOUABAIN; OUABAIN; STEROID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM BALANCE; SODIUM CELL LEVEL; SODIUM TRANSPORT;

ANIMALS; CALCIUM; CARDIOTONIC AGENTS; CELLS, CULTURED; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; HIPPOCAMPUS; ISOENZYMES; NA(+)-K(+)-EXCHANGING ATPASE; NEUROGLIA; NEURONS; OUABAIN; POTASSIUM; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 0032496727     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00224-8     Document Type: Article

References (68)

1. F.J. Alvarez-Leefman, H. Cruzblanca, S.M. Gamino, J. Altamirano, A. Nani, L. Reuss, Transmembrane ion movements elicited by sodium pump inhibition in Helix aspersa neurons, J. Neurophysiol. 71 (1994) 1787-1796.
2. L. Ballerini, E. Bracci, A. Nistri, Pharmacological block of the electrogenic sodium pump disrupts rhythmic busting induced by strychnine and bicuculline in the neonatal rat spinal cord, J. Neurophysiol. 77 (1997) 17-23.
3. G.A. Banker, W.M. Cowan, Rat hippocampal neurons in dispersed cell culture, Brain Res. 126 (1977) 337-342.
4. B. Barbour, H. Brew, D. Attwell, Electrogenic glutamate uptake in glial cells is activated by intracellular potassium, Nature 335 (1988) 433-435.
5. D.L. Benson, P.A. Cohen, Activity-independent segregation of excitatory and inhibitory synaptic terminals in cultured hippocampal neurons, J. Neurosci. 16 (1996) 6424-6432.
6. G. Blanco, G. Berberian, L. Beaugé, Detection of a highly ouabain sensitive isoform of rat brainstem Na,K-ATPase, Biochim. Biophys. Acta. 1027 (1990) 1-7.
7. 2+ stores and cell responsiveness, Am. J. Physiol. 264 (1993) C1367-C1387.
8. M.P. Blaustein, M. Juhaszova, V.A. Golovina, The cellular mechanism of action of cardiotonic steroids: A new hypothesis, Clin. Exper. Hypertens. 1998, in press.
9. + in resting and activated A7r5 vascular smooth muscle cells, Am. J. Physiol. 264 (1993) C1513-C1524.
10. M.L. Brines, A.O. Dare, N.C. de Lanerolle, The cardiac glycoside ouabain potentiates excitotoxic injury of adult neurons in rat hippocampus, Neurosci. Lett. 191 (1995) 145-148.
11. M.L. Brines, R.J. Robbins, Inhibition of α2/α3 sodium pump isoforms potentiates glutamate neurotoxicity, Brain Res. 591 (1992) 94-102.
12. +-ATPase on the membrane potentials and neurotransmitter efflux in rat brain slices, Brain Res. 334 (1985) 125-137.
13. A.S. Budzikowski, F.H. Leenen, Brain ouabain in the median preoptic nucleus mediates sodium-sensitive hypertension in spontaneously hypertensive rats, Hypertension. 29 (1997) 599-605.
14. + ATPase, Eur. J. Neurosci. 7 (1995) 1674-1683.
15. 2+ waves in astrocytes, Cell Calcium. 12 (1991) 185-204.
16. J.W. Dani, A. Chernjavsky, S.J. Smith, Neuronal activity triggers calcium waves in hippocampal astrocyte networks, Neuron. 8 (1992) 429-440.
17. J.W. Dani, S.J. Smith, The triggering of astrocytic calcium waves by NMDA-induced neuronal activation, Ciba Foundation Symposium 188 (1995) 195-205.
18. T.A. Fletcher, P. Cameron, P.D. De Camilli, G. Banker, The distribution of synapsin I and synapotophysin in hippocampal neurons in developing culture, J. Neurosci. 11 (1991) 1617-1626.
19. G. Fontana, R.S. Rogowski, M.P. Blaustein, Kinetic properties of the sodium-calcium exchanger in rat brain synaptosomes, J. Physiol. 485 (1995) 349-364.
20. M.P. Goldberg, D.W. Choi, Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium independent mechanisms of neuronal injury, J. Neurosci. 13 (1993) 3510-3524.
21. W.F. Goldman, P.J. Yarowsky, M. Juhaszova, B.K. Krueger, M.P. Blaustein, Sodium/Calcium exchange in rat cortical astrocytes, J. Neurosci. 14 (1994) 5834-5843.
22. 2+ exchanger, Glia. 16 (1996) 296-305.
23. M.M. Haglund, P.A. Schwartzkroin, Role of Na-K pump potassium regulation and IPSPs in seizures and spreading depression in immature rabbit hippocampal slices, J. Neurophysiol. 63 (1990) 225-239.
24. J.M. Hamlyn, M.P. Blaustein, S. Bova, D.W. DuCharme, D.W. Harris, F. Mandel, W.R. Mathews, J.H. Ludens, Identification and characterization of a ouabain-like compound from human plasma, Proc. Natl. Acad. Sci. USA 88 (1991) 6259-6263.
25. B.S. Huang, X. Huang, E. Harmsen, F.H. Leenen, Chronic central versus peripheral ouabain, blood pressure, and sympathetic activity in rats, Hypertension. 23 (1994) 1087-1090.
26. E.A. Jewell, J.B. Lingrel, Comparison of substrate dependence properties of the rat Na,K-ATPase α1, α2 and α3 isoforms expressed in HeLa cells, J. Biol. Chem. 266 (1991) 16925-16930.
27. M.G. Judd, T.N. Nagaraja, Brookes, Potassium-induced stimulation of glutamate uptake in mouse cerebral astrocytes: The role of intracellular pH, J Neurochem. 66 (1996) 169-176.
28. + pump low and high ouabain affinity a subunit isoforms are differently distributed in cells, Proc. Natl. Acad. Sci. USA. 94 (1997) 1800-1805.
29. + pump a subunit isoforms in plasmalemma: physiological implications, Ann. NY. Acad. Sci. 834 (1997) 524-535.
30. L. Kiedrowski, G. Brooker, E. Costa, J.T. Wroblewski, Glutamate impairs neuronal calcium extrusion while reducing sodium gradient, Neuron. 12 (1994) 295-300.
31. R.A. Koch, M.E. Barish, Pertubation of intracellular calcium and hydrogen ion regulation in cultured mouse hippocampal neurons by reduction of the sodium ion concentration gradient, J Neurosci. 14 (1994) 2585-2593.
32. J. Laredo, J.R. Shah, Z.R. Lu, B.P. Hamilton, J.M. Hamlyn, Angiotensin II stimulates secretion of endogenous ouabain from bovine adrenocortical cells via angiotensin type 2 receptors, Hypertension. 29 (1997) 401-407.
33. N. Leblanc, J.R. Hume, Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum, Science. 248 (1990) 372-376.
34. G.J. Lees, Inhibition of sodium-potassium-ATPase: a potentially ubiquitous mechanism contributing to central nervous system neuropathology, Brain Res. Rev. 16 (1991) 283-300.
35. R. Levenson, Isoforms of the Na,K-ATPase: family members in search of function, Rev. Physiol. Biochem. and Pharmacol. 123 (1994) 1-45.
36. P.W. Luther, R.K. Yip, R.J. Bloch, A. Ambesi, G.E. Lindenmayer, M.P. Blaustein, Presynaptic localization of sodium/calcium exchangers in neuromuscular preparations, J. Neurosci. 12 (1992) 4898-4904.
37. 2+ imaging of CNS axons in culture indicates reliable coupling between single action potentials and distal functional release sites, Neuron. 16 (1996) 783-795.
38. J.E. Madl, K. Burgesser, Adenosine triphosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices, J. Neurosci. 13 (1993) 4429-4444.
39. 2+ homeostasis and cell death, J. Neurosci. 15 (1995) 6239-6249.
40. 2+-dependent conductance, J. Neurophysiol. 57 (1987) 496-509.
41. K.M. McGrail, J.M. Phillips, K.J. Sweadner, Immunofluorescent localization of three Na,K-ATPase isozymes in the rat central nervous system: both neurons and glia can express more than one Na,K-ATPase, J. Neurosci. 11 (1991) 381-391.
42. T.H. Murphy, L.A. Blatter, W.G. Wier, J.M. Baraban, Spontaneous synchronous synaptic calcium transients in cultured cortical neurons, J. Neurosci. 12 (1992) 4834-4845.
43. + )-ATPase isozymes for cardioactive steriods, role of lactone ring, sugar moiety and KCl concentration, Biochem. Pharmacol. 40 (1990) 2611-2616.
44. 2+ fluorometry, Neurosci. Lett. 78 (1987) 69-74.
45. F.W. Pfrieger, B.A. Barres, Synaptic efficacy enhanced by glial cell in vitro, Science. 277 (1997) 1684-1687.
46. G. Pietrini, M. Matteoli, G. Banker, M.J. Caplan, Isoforms of the Na,K-ATPase are present in both axons and dendrites of hippocampal neurons in culture, Proc. Natl. Acad. Sci. USA. 89 (1992) 8414-8418.
47. +-ATPaSe, Am. J. Physiol. 262 (1992) C743-C751.
48. R.D. Randall, S.A. Thayer, Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocam-pal neurons, J. Neurosci. 12 (1992) 1882-1895.
49. 2+ exchanger in presynaptic boutons of hippocampal cells in culture, Neuron. 15 (1995) 1077-1084.
50. H.P. Robinson, M. Kawahara, Y. Jimbo, K. Torimitsu, Y. Kuroda, A. Kawana, Periodic synchronized bursting and intracellular calcium transients elicited by low magnesium in cultured cortical neurons, J. Neurophysiol. 70 (1993) 1606-1616.
51. C.R. Rose, B.R. Ransom, Intracellular sodium homeostasis in rat hippocampal astrocytes, J. Physiol. (Lond). 491 (1996) 291-305.
52. C.R. Rose, B.R. Ransom, Intracellular sodium homeostasis in rat hippocampal neurons, J. Physiol. (Lond). 499 (1997) 573-587.
53. 2+ in nerve terminals, Am. J. Physiol. 252 (1987) C595-C603.
54. M.S. Santos, A.J. Moreno, A.P. Carvalho, Relationships between ATP depletion, membrane potential, and the release of neurotransmitters in rat nerve terminals, Stroke. 27 (1996) 941-950.
55. M. Segal, Imaging of calcium variation in living dendrites spines of cultured hippocampal neurons, J. Physiol. (Lond). 486 (1995) 283-295.
56. +-ATPase alpha-subunit gene is expressed in testis, Proc. Nat. Acad. Sci. USA. 91 (1994) 12952-12956.
57. M. Shen, T.M. Piser, V.S. Seybold, S.A. Thayer, Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures, J. Neurosci. 16 (1996) 4322-4334.
58. +-ATPaSe a-subunit from rat brain, Biochemistry. 25 (1986) 8125-8131.
59. +-ATPase, Biochim. Biophys. Acta. 988 (1989) 185-220.
60. K.J. Sweadner, Overlapping and diverse distribution of Na-K AT-Pase in neurons and glia, Can. J. Physiol. Pharmacol. 70 (1992) S255-S259.
61. +-ATPase a-subunit isoforms in evolution, Am. J. Physiol. 259 (1990) C619-C630.
62. T. Tanaka, H. Saito, N. Matsuki, Intracellular calcium oscillation in cultured rat hippocampal neuron a model for glutamatergic neuro-transmission, Jpn. J. Pharmacol. 70 (1996) 89-93.
63. T. Tanaka, H. Saito, N. Matsuki, Basic fibroblast growth factor modulates synaptic transmission in cultured rat hippocampal neurons, Brain Res. 723 (1996) 190-195.
64. A.G. Therien, N.B. Nestor, W.J. Ball, R. Blostein, Tissue-specific verses isoform-specific differences in cation activation of the Na,K-ATPase, J. Biol. Chem. 271 (1996) 7104-7112.
65. M.F. Wendt-Gallitelli, T. Voight, G. Isenberg, Microheterogeneity of subsarcolemmal sodium gradients, electron probe microanalysis in guinea pig ventricular myocytes, J. Physiol. (Lond). 472 (1993) 33-44.
66. +-ATPaSe is associated with sites of cardiac and neuromuscular impulse transmission, Circ. Res. 78 (1996) 870-879.
67. R. Zahler, Z. Zhong-Ting, M. Manor, W.F. Boron, Sodium kinetics of Na,K-ATPase a isoforms in intact transfected HeLa cells, J. Gen. Physiol. 110 (1997) 201-213.
68. N. Zhao, L.C. Lo, N. Berova, K. Nakanishi, A.A. Tymiak, J.H. Ludens, G.T. Haupert Jr., Na,K-ATPase inhibitors from bovine hypothalamus and human plasma are different from ouabain: nanogram scale CD structural analysis, Biochemistry. 34 (1995) 9893-9896.