Transporter engineering for improved tolerance against alkane biofuels in Saccharomyces cerevisiae

Biotechnology for Biofuels

Volumn 6, Issue 1, 2013, Pages

  Chen, Binbin ^a   Ling, Hua ^a   Chang, Matthew Wook ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

ABC transporters; Alkanes; Biofuels; S. cerevisiae; Tolerance

Indexed keywords

ABC TRANSPORTER; BIOFUEL PRODUCTION; BIOLOGICAL PRODUCTION; HETEROLOGOUS EXPRESSION; S.CEREVISIAE; SITE DIRECTED MUTAGENESIS; TOLERANCE LIMITS; YARROWIA LIPOLYTICA;

AMINO ACIDS; BIOFUELS; CARBOXYLATION; CELL ENGINEERING; ENZYME ACTIVITY; FITS AND TOLERANCES; MOLECULAR BIOLOGY; YEAST;

PARAFFINS;

ALKANE; BIOFUEL; HYDROCARBON; HYDROLYSIS; TOLERANCE; TOXICITY; YEAST;

SACCHAROMYCES CEREVISIAE; YARROWIA LIPOLYTICA;

EID: 84874818199     PISSN: 17546834     EISSN: None     Source Type: Journal    
DOI: 10.1186/1754-6834-6-21     Document Type: Article

References (46)

1. Bioethanol production from xylose by recombinant Saccharomyces cerevisiae expressing xylose reductase, NADP(+)-dependent xylitol dehydrogenase, and xylulokinase. Matsushika A, Watanabe S, Kodaki T, Makino K, Sawayama S, J Biosci Bioeng 2008 105 3 296 299 (Pubitemid 351467199)
2. Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol. Steen EJ, Chan R, Prasad N, Myers S, Petzold CJ, Redding A, Ouellet M, Keasling JD, Microb Cell Fact 2008 7 36
3. Synthesis of novel lipids in saccharomyces cerevisiae by heterologous expression of an unspecific bacterial acyltransferase. Kalscheuer R, Luftmann H, Steinbuchel A, Appl Environ Microbiol 2004 70 12 7119 7125 (Pubitemid 39643775)
4. Synthesis of FAEEs from glycerol in engineered Saccharomyces cerevisiae using endogenously produced ethanol by heterologous expression of an unspecific bacterial acyltransferase. Yu KO, Jung J, Kim SW, Park CH, Han SO, Biotechnol Bioeng 2012 109 1 110 115
5. Functional expression and characterization of five wax ester synthases in Saccharomyces cerevisiae and their utility for biodiesel production. Shi S, Valle-Rodriguez JO, Khoomrung S, Siewers V, Nielsen J, Biotechnol Biofuels 2012 5 1 7
6. Systems biology of yeast: enabling technology for development of cell factories for production of advanced biofuels. de Jong B, Siewers V, Nielsen J, Curr Opin Biotechnol 2012 23 4 624 630
7. Bio-resolution of a chiral epoxide using whole cells of Bacillus megaterium ECU1001 in a biphasic system. Gong P-F, Xu J-H, Enzyme Microb Technol 2005 36 2-3 252 257 (Pubitemid 40039079)
8. Improving enzymes by using them in organic solvents. Klibanov AM, Nature 2001 409 6817 241 246 (Pubitemid 32144293)
9. Variability of hydrocarbon and fatty acid components in cultures of the filamentous cyanobacterium scytonema sp. Isolated from microbial community "black cover" of limestone walls in Jerusalem. Dembitsky VM, Srebnik M, Biochem (Mosc) 2002 67 11 1276 1282
10. Microbial biosynthesis of alkanes. Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB, Science 2010 329 5991 559 562
11. Insect pheromones-an overview of biosynthesis and endocrine regulation. Tillman JA, Seybold SJ, Jurenka RA, Blomquist GJ, Insect Biochem Mol Biol 1999 29 6 481 514 (Pubitemid 29297127)
12. Sealing plant surfaces: cuticular wax formation by epidermal cells. Samuels L, Kunst L, Jetter R, Annu Rev Plant Biol 2008 59 683 707 (Pubitemid 351813047)
13. Expanding the product profile of a microbial alkane biosynthetic pathway. Harger M, Zheng L, Moon A, Ager C, An JH, Choe C, Lai Y-L, Mo B, Zong D, Smith MD, et al. ACS Synthetic Biol 2013 2 1 59 62
14. Bernard A, Domergue F, Pascal S, Jetter R, Renne C, Faure J-D, Haslam RP, Napier JA, Lessire R, Joubès J, Reconstitution of Plant Alkane Biosynthesis in Yeast Demonstrates That Arabidopsis ECERIFERUM1 and ECERIFERUM3 Are Core Components of a Very-Long-Chain Alkane Synthesis Complex Online: The Plant Cell 2012
15. Toxicity of n-Alkanes, n-Alk-1-enes, n-Alkan-1-ols and n-Alkyl-1-bromides towards Yeasts. Gill CO, Ratledge C, J Gen Microbiol 1972 72 1 165 172
16. Mechanisms of solvent tolerance in gram-negative bacteria. Ramos JL, Duque E, Gallegos MT, Godoy P, Ramos-Gonzalez MI, Rojas A, Teran W, Segura A, Annu Rev Microbiol 2002 56 743 768 (Pubitemid 35217473)
17. A Pseudomonas thrives in high concentrations of toluene. Inoue A, Horikoshi K, Nature 1989 338 6212 264 266 (Pubitemid 19086929)
18. Preparation of an organic solvent-tolerant strain from baker's yeast. Kawamoto T, Kanda T, Tanaka A, Appl Microbiol Biotechnol 2001 55 4 476 479 (Pubitemid 32417848)
19. Engineering yeast transcription machinery for improved ethanol tolerance and production. Alper H, Moxley J, Nevoigt E, Fink GR, Stephanopoulos G, Science 2006 314 5805 1565 1568 (Pubitemid 44907143)
20. Development of ethanologenic bacteria. Jarboe LR, Grabar TB, Yomano LP, Shanmugan KT, Ingram LO, Adv Biochem Eng Biotechnol 2007 108 237 261 (Pubitemid 47434548)
21. Engineering microbial biofuel tolerance and export using efflux pumps. Dunlop MJ, Dossani ZY, Szmidt HL, Chu HC, Lee TS, Keasling JD, Hadi MZ, Mukhopadhyay A, Mol Syst Biol 2011 7 487
22. Generation and characterisation of stable ethanol-tolerant mutants of Saccharomyces cerevisiae. Stanley D, Fraser S, Chambers PJ, Rogers P, Stanley GA, J Ind Microbiol Biotechnol 2010 37 2 139 149
23. Improved production of ethanol by novel genome shuffling in Saccharomyces cerevisiae. Hou L, Appl Biochem Biotechnol 2010 160 4 1084 1093
24. Identification and reconstitution of genetic regulatory networks for improved microbial tolerance to isooctane. Kang A, Chang MW, Mol Biosyst 2012 8 4 1350 1358
25. Increased expression of the yeast multidrug resistance ABC transporter Pdr18 leads to increased ethanol tolerance and ethanol production in high gravity alcoholic fermentation. Teixeira M, Godinho C, Cabrito T, Mira N, Sá-Correia I, Microb Cell Fact 2012 11 1 1 9
26. Yarrowia lipolytica: A model and a tool to understand the mechanisms implicated in lipid accumulation. Beopoulos A, Chardot T, Nicaud JM, Biochimie 2009 91 6 692 696
27. Physiology and genetics of the dimorphic fungus Yarrowia lipolytica. Barth G, Gaillardin C, FEMS Microbiol Rev 1997 19 4 219 237 (Pubitemid 27225687)
28. Insertional Mutagenesis in the n-Alkane-Assimilating Yeast Yarrowia lipolytica: Generation of Tagged Mutations in Genes Involved in Hydrophobic Substrate Utilization. Mauersberger S, Wang HJ, Gaillardin C, Barth G, Nicaud JM, J Bacteriol 2001 183 17 5102 5109 (Pubitemid 32750938)
29. Characterization of Yarrowia lipolytica mutants affected in hydrophobic substrate utilization. Thevenieau F, Le Dall MT, Nthangeni B, Mauersberger S, Marchal R, Nicaud JM, Fungal Genet Biol 2007 44 6 531 542 (Pubitemid 46679290)
30. Uptake and Assimilation of Hydrophobic Substrates by the Oleaginous Yeast Yarrowia lipolytica. Thevenieau F, Beopoulos A, Desfougeres T, Sabirova J, Albertin K, Zinjarde S, Nicaud JM, Handbook of Hydrocarbon and Lipid Microbiology Berlin Heidelberg: Timmis. Springer-Verlag, Kenneth N, 2010 1513 1527
31. Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters. Moody JE, Millen L, Binns D, Hunt JF, Thomas PJ, J Biol Chem 2002 277 24 21111 21114 (Pubitemid 34952244)
32. H662 is the linchpin of ATP hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB. Zaitseva J, Jenewein S, Jumpertz T, Holland IB, Schmitt L, EMBO J 2005 24 11 1901 1910 (Pubitemid 40896162)
33. Structure and mechanism of ABC transporters. Schmitt L, Tampé R, Curr Opin Struct Biol 2002 12 6 754 760 (Pubitemid 36009492)
34. Toward understanding the mechanism of action of the yeast multidrug resistance transporter Pdr5p: a molecular modeling study. Rutledge RM, Esser L, Ma J, Xia D, J Struct Biol 2011 173 2 333 344
35. A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5. Ernst R, Kueppers P, Klein CM, Schwarzmueller T, Kuchler K, Schmitt L, Proc Natl Acad Sci USA 2008 105 13 5069 5074 (Pubitemid 351738511)
36. Enhanced secretory production of hemolysin-mediated cyclodextrin glucanotransferase in Escherichia coli by random mutagenesis of the ABC transporter system. Low KO, Mahadi NM, Abdul Rahim R, Rabu A, Abu Bakar FD, Abdul Murad AM, Illias RM, J Biotechnol 2010 150 4 453 459
37. Casein Kinase I-dependent Phosphorylation and Stability of the Yeast Multidrug Transporter Pdr5p. Decottignies A, Owsianik G, Ghislain M, J Biol Chem 1999 274 52 37139 37146
38. Candida glabrata ATP-binding cassette transporters Cdr1p and Pdh1p expressed in a Saccharomyces cerevisiae strain deficient in membrane transporters show phosphorylation-dependent pumping properties. Wada S, Niimi M, Niimi K, Holmes AR, Monk BC, Cannon RD, Uehara Y, J Biol Chem 2002 277 48 46809 46821 (Pubitemid 35417685)
39. Genetic Separation of FK506 Susceptibility and Drug Transport in the Yeast Pdr5 ATP-binding Cassette Multidrug Resistance Transporter. Egner R, Rosenthal FE, Kralli A, Sanglard D, Kuchler K, Mol Biol Cell 1998 9 2 523 543 (Pubitemid 28084142)
40. Gene splicing and mutagenesis by PCR-driven overlap extension. Heckman KL, Pease LR, Nat Protoc 2007 2 4 924 932 (Pubitemid 46758810)
41. Optimized cassettes for fluorescent protein tagging in Saccharomyces cerevisiae. Sheff MA, Thorn KS, Yeast 2004 21 8 661 670 (Pubitemid 38868184)
42. ESCRT-I components of the endocytic machinery are required for Rim101-dependent ambient pH regulation in the yeast Yarrowia lipolytica. Blanchin-Roland S, Da Costa G, Gaillardin C, Microbiology 2005 151 Pt 11 3627 3637 (Pubitemid 41632073)
43. Import of proteins into mitochondria: a 70 kDa outer membrane protein with a large carboxy-terminal deletion is still transported to the outer membrane. Riezmant H, Hase T, Loon APGM, Grivell LA, Suda K, Schatz G, European Mol Biol Organ J 1983 2 12 2161 2168
44. A major 125-kd membrane glycoprotein of Saccharomyces cerevisiae is attached to the lipid bilayer through an inositol-containing phospholipid. Conzelmann A, Riezman H, Desponds C, Bron C, European Mol Biol Organ J 1988 7 7 2233 2240
45. PPARα controls the intracellular coenzyme A concentration via regulation of PANK1α gene expression. Ramaswamy G, Karim MA, Murti KG, Jackowski S, J Lipid Res 2004 45 1 17 31 (Pubitemid 38176611)
46. Activation of hypoxia-inducible factor 1 during macrophage differentiation. Oda T, Hirota K, Nishi K, Takabuchi S, Oda S, Yamada H, Arai T, Fukuda K, Kita T, Adachi T, et al. Am J Physiol Cell Physiol 2006 291 1 104 C113