Disrupting the PIKE-A/Akt interaction inhibits glioblastoma cell survival, migration, invasion and colony formation

Oncogene

Volumn 32, Issue 8, 2013, Pages 1030-1040

  Qi, Q ^a   He, K ^a   Liu, X ^a   Pham, C ^a   Meyerkord, C ^a,b   Fu, H ^a,b   Ye, K ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

Akt; glioblastoma; PIKE A; protein protein interaction

Indexed keywords

CYCLIN DEPENDENT KINASE 4; PIKE A PROTEIN; PROTEIN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ARTICLE; CANCER GROWTH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; FLUORESCENCE; GENE DISRUPTION; GENE INTERACTION; GENE REPRESSION; GENETIC ASSOCIATION; GENETIC COMPLEMENTATION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; GLIOBLASTOMA; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; PEPTIDES; PHOSPHORYLATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTO-ONCOGENE PROTEINS C-AKT; TRANSFECTION;

EID: 84874781438     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.109     Document Type: Article

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