Metabolic Adaptation to Chronic Inhibition of Mitochondrial Protein Synthesis in Acute Myeloid Leukemia Cells

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Jhas, Bozhena ^a   Sriskanthadevan, Shrivani ^a   Skrtic, Marko ^a   Sukhai, Mahadeo A ^a   Voisin, Veronique ^b   Jitkova, Yulia ^a   Gronda, Marcela ^a   Hurren, Rose ^a   Laister, Rob C ^a   Bader, Gary D ^b,c   Minden, Mark D ^a   Schimmer, Aaron D ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; MESSENGER RNA; MITOCHONDRIAL PROTEIN; TIGECYCLINE;

ACUTE GRANULOCYTIC LEUKEMIA; AEROBIC METABOLISM; ANTIBIOTIC RESISTANCE; ARTICLE; BINDING SITE; CELL DEATH; CELL GROWTH; CELL POPULATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; GLYCOLYSIS; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; METABOLIC STRESS; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PHENOTYPE; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; UPREGULATION;

ANTI-BACTERIAL AGENTS; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION REGULATION, LEUKEMIC; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LEUKEMIA, MYELOID, ACUTE; MINOCYCLINE; MITOCHONDRIAL PROTEINS; NEOPLASM PROTEINS; OXYGEN CONSUMPTION; PROTEIN BIOSYNTHESIS;

EID: 84874772177     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058367     Document Type: Article

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