메뉴 건너뛰기




Volumn 121, Issue 3-4, 2013, Pages

Reducing serum uric acid attenuates TGF-β1-induced profibrogenic progression in type 2 diabetic nephropathy

Author keywords

Diabetic nephropathy; Epithelial mesenchymal transition; Hyperuricemia; TGF 1

Indexed keywords

ALBUMIN; ALLOPURINOL; ALPHA SMOOTH MUSCLE ACTIN; CREATININE; MITOGEN ACTIVATED PROTEIN KINASE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; URIC ACID; UVOMORULIN; VIMENTIN;

EID: 84874763194     PISSN: None     EISSN: 16602129     Source Type: Journal    
DOI: 10.1159/000343567     Document Type: Article
Times cited : (42)

References (31)
  • 2
    • 0033005975 scopus 로고    scopus 로고
    • Reappraisal of the pathogenesis and consequences of hyperuricemia in hypertension, cardiovascular disease, and renal disease
    • Johnson RJ, Kivlighn SD, Kim YG, Suga S, Fogo AB: Reappraisal of the pathogenesis and consequences of hyperuricemia in hypertension, cardiovascular disease, and renal disease. Am J Kidney Dis 1999; 33: 225-234. (Pubitemid 29072223)
    • (1999) American Journal of Kidney Diseases , vol.33 , Issue.2 , pp. 225-234
    • Johnson, R.J.1    Kivlighn, S.D.2    Kim, Y.-G.3    Suga, S.4    Fogo, A.B.5
  • 4
    • 0025837540 scopus 로고
    • Uric acid stimulates vascular smooth muscle cell proliferation by increasing platelet-derived growth factor A-chain expression
    • Rao GN, Corson MA, Berk BC: Uric acid stimulates vascular smooth muscle cell proliferation by increasing platelet-derived growth factor A-chain expression. J Biol Chem 1991; 266: 8604-8608. (Pubitemid 21906552)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.13 , pp. 8604-8608
    • Rao, G.N.1    Corson, M.A.2    Berk, B.C.3
  • 5
    • 0038579374 scopus 로고    scopus 로고
    • Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2
    • DOI 10.1161/01.HYP.0000072820.07472.3B
    • Kanellis J, Watanabe S, Li JH, Kang DH, Li P, Nakagawa T, Wamsley A, Sheikh-Hamad D, Lan HY, Feng L, Johnson RJ: Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2. Hypertension 2003; 41: 1287-1293. (Pubitemid 36706079)
    • (2003) Hypertension , vol.41 , Issue.6 , pp. 1287-1293
    • Kanellis, J.1    Watanabe, S.2    Li, J.H.3    Kang, D.H.4    Li, P.5    Nakagawa, T.6    Wamsley, A.7    Sheikh-Hamad, D.8    Lan, H.Y.9    Feng, L.10    Johnson, R.J.11
  • 6
    • 0037047070 scopus 로고    scopus 로고
    • Allopurinol improves endothelial dysfunction in chronic heart failure
    • DOI 10.1161/01.CIR.0000022140.61460.1D
    • Farquharson CA, Butler R, Hill A, Belch JJ, Struthers AD: Allopurinol improves endothelial dysfunction in chronic heart failure. Circulation 2002; 106: 221-226. (Pubitemid 34761303)
    • (2002) Circulation , vol.106 , Issue.2 , pp. 221-226
    • Farquharson, C.A.J.1    Butler, R.2    Hill, A.3    Belch, J.J.F.4    Struthers, A.D.5
  • 7
    • 0037024270 scopus 로고    scopus 로고
    • Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: Results from 2 placebo-controlled studies
    • DOI 10.1161/01.CIR.0000017502.58595.ED
    • Doehner W, Schoene N, Rauchhaus M, Leyva-Leon F, Pavitt DV, Reaveley DA, Schuler G, Coats AJ, Anker SD, Hambrecht R: Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from two placebo-controlled studies. Circulation 2002; 105: 2619-2624. (Pubitemid 34596038)
    • (2002) Circulation , vol.105 , Issue.22 , pp. 2619-2624
    • Doehner, W.1    Schoene, N.2    Rauchhaus, M.3    Leyva-Leon, F.4    Pavitt, D.V.5    Reaveley, D.A.6    Schuler, G.7    Coats, A.J.S.8    Anker, S.D.9    Hambrecht, R.10
  • 8
    • 0034065857 scopus 로고    scopus 로고
    • Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension
    • Butler R, Morris AD, Belch JJ, Hill A, Struthers AD: Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension. Hypertension 2000; 35: 746-751. (Pubitemid 30165320)
    • (2000) Hypertension , vol.35 , Issue.3 , pp. 746-751
    • Butler, R.1    Morris, A.D.2    Belch, J.J.F.3    Hill, A.4    Struthers, A.D.5
  • 9
    • 0036014928 scopus 로고    scopus 로고
    • Smad7 inhibits fibrotic effect of TGF-on renal tubular epithelial cells by blocking Smad2 activation
    • Li JH, Zhu HJ, Huang XR, Lai KN, Johnson RJ, Lan HY: Smad7 inhibits fibrotic effect of TGF-on renal tubular epithelial cells by blocking Smad2 activation. J Am Soc Nephrol 2002; 13: 1464-1472.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1464-1472
    • Li, J.H.1    Zhu, H.J.2    Huang, X.R.3    Lai, K.N.4    Johnson, R.J.5    Lan, H.Y.6
  • 10
  • 11
    • 0030670132 scopus 로고    scopus 로고
    • Early role of Fsp1 in epithelial-mesenchymal transformation
    • Okada H, Danoff TM, Kalluri R, Neilson EG: Early role of Fsp1 in epithelial-mesenchymal transformation. Am J Physiol 1997; 273: F563-F574.
    • (1997) Am J Physiol , vol.273
    • Okada, H.1    Danoff, T.M.2    Kalluri, R.3    Neilson, E.G.4
  • 12
    • 24644487312 scopus 로고    scopus 로고
    • TGF-and epithelial-to-mesenchymal transitions
    • Zavadil J, Bottinger EP: TGF-and epithelial-to-mesenchymal transitions. Oncogene 2005; 24: 5764-5774.
    • (2005) Oncogene , vol.24 , pp. 5764-5774
    • Zavadil, J.1    Bottinger, E.P.2
  • 15
    • 0036098930 scopus 로고    scopus 로고
    • An increase in the cell component of the cortical interstitium antedates interstitial fibrosis in type 1 diabetic patients
    • Katz A, Caramori ML, Sisson-Ross S, Groppoli T, Basgen JM, Mauer M: An increase in the cell component of the cortical interstitium antedates interstitial fibrosis in type 1 diabetic patients. Kidney Int 2002; 61: 2058-2066.
    • (2002) Kidney Int , vol.61 , pp. 2058-2066
    • Katz, A.1    Caramori, M.L.2    Sisson-Ross, S.3    Groppoli, T.4    Basgen, J.M.5    Mauer, M.6
  • 16
    • 0036138824 scopus 로고    scopus 로고
    • Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis
    • Yang J, Liu Y: Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis. J Am Soc Nephrol 2002; 13: 96-107. (Pubitemid 34042016)
    • (2002) Journal of the American Society of Nephrology , vol.13 , Issue.1 , pp. 96-107
    • Yang, J.1    Liu, Y.2
  • 17
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-1-induced epithelial-tomesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R: BMP-7 counteracts TGF-1-induced epithelial-tomesenchymal transition and reverses chronic renal injury. Nat Med 2003; 9: 964-968.
    • (2003) Nat Med , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3    Mammoto, T.4    Charytan, D.5    Strutz, F.6    Kalluri, R.7
  • 18
    • 0036785218 scopus 로고    scopus 로고
    • Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice
    • Yang J, Dai C, Liu Y: Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice. J Am Soc Nephrol 2002; 13: 2464-2477.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2464-2477
    • Yang, J.1    Dai, C.2    Liu, Y.3
  • 19
    • 0036236193 scopus 로고    scopus 로고
    • Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction
    • DOI 10.1046/j.1523-1755.2002.00328.x
    • Nagatoya K, Moriyama T, Kawada N, Takeji M, Oseto S, Murozono T, Ando A, Imai E, Hori M: Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction. Kidney Int 2002; 61: 1684-1695. (Pubitemid 34437922)
    • (2002) Kidney International , vol.61 , Issue.5 , pp. 1684-1695
    • Nagatoya, K.1    Moriyama, T.2    Kawada, N.3    Takeji, M.4    Oseto, S.5    Murozono, T.6    Ando, A.7    Imai, E.8    Hori, M.9
  • 20
    • 0141720342 scopus 로고    scopus 로고
    • Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis
    • DOI 10.1172/JCI200317913
    • Li Y, Yang J, Dai C, Wu C, Liu Y: Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis. J Clin Invest 2003; 112: 503-516. (Pubitemid 38056335)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.4 , pp. 503-516
    • Li, Y.1    Yang, J.2    Dai, C.3    Wu, C.4    Liu, Y.5
  • 23
    • 0035906987 scopus 로고    scopus 로고
    • Epithelial mesenchymal interactions in cancer and development
    • DOI 10.1016/S0092-8674(01)00365-8
    • Arias AM: Epithelial mesenchymal interactions in cancer and development. Cell 2001; 105: 425-431. (Pubitemid 32520849)
    • (2001) Cell , vol.105 , Issue.4 , pp. 425-431
    • Arias, A.M.1
  • 25
    • 0030428267 scopus 로고    scopus 로고
    • E-cadherin transforms embryonic corneal fibroblasts to stratified epithelium with desmosomes
    • Vanderburg CR, Hay ED: E-cadherin transforms embryonic corneal fibroblasts to stratified epithelium with desmosomes. Acta Anat (Basel) 1996; 157: 87-104. (Pubitemid 27207349)
    • (1996) Acta Anatomica , vol.157 , Issue.2 , pp. 87-104
    • Vanderburg, C.R.1    Hay, E.D.2
  • 29
    • 0036224781 scopus 로고    scopus 로고
    • Xanthine oxidase is involved in free radical production in type 1 diabetes: Protection by allopurinol
    • Desco MC, Asensi M, Marquez R, Martinez-Valls J, Vento M, Pallardo FV, Sastre J, Vina J: Xanthine oxidase is involved in free radical production in type 1 diabetes: protection by allopurinol. Diabetes 2002; 51: 1118-1124. (Pubitemid 34438358)
    • (2002) Diabetes , vol.51 , Issue.4 , pp. 1118-1124
    • Desco, M.-C.1    Asensi, M.2    Marquez, R.3    Martinez-Valls, J.4    Vento, M.5    Pallardo, F.V.6    Sastre, J.7    Vina, J.8
  • 30
    • 0038476475 scopus 로고    scopus 로고
    • Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice
    • DOI 10.1080/1071576031000107344
    • Matsumoto S, Koshiishi I, Inoguchi T, Nawata H, Utsumi H: Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice. Free Radic Res 2003; 37: 767-772. (Pubitemid 36626436)
    • (2003) Free Radical Research , vol.37 , Issue.7 , pp. 767-772
    • Matsumoto, S.1    Koshiishi, I.2    Inoguchi, T.3    Nawata, H.4    Utsumi, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.