Glomerular changes in the KK-Ay/Ta mouse: A possible model for human type 2 diabetic nephropathy

Nephrology

Volumn 11, Issue 1, 2006, Pages 29-35

  Ito, Takamichi ^a   Tanimoto, Mitsuo ^a   Yamada, Kaori ^a   Kaneko, Shigeru ^a   Matsumoto, Masakazu ^a   Obayashi, Keiko ^a   Hagiwara, Shinji ^a   Murakoshi, Maki ^a   Aoki, Tatsuya ^a   Wakabayashi, Michiro ^a   Gohda, Tomohito ^a   Funabiki, Kazuhiko ^a   Maeda, Kunimi ^a   Horikoshi, Satoshi ^a   Tomino, Yasuhiko ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Advanced glycation end products; Diabetic nephropathy; KK mouse; Pathology; Transforming growth factor beta

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALBUMIN; CREATININE; GLUCOSE; HEMOGLOBIN A1C; PEROXIDASE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BLOOD PRESSURE; BODY WEIGHT; CONTROLLED STUDY; CREATININE CLEARANCE; DIABETIC NEPHROPATHY; DIET RESTRICTION; DISEASE COURSE; DISEASE SEVERITY; ELECTRON MICROSCOPY; GLOMERULUS; GLUCOSE BLOOD LEVEL; HEMOGLOBIN DETERMINATION; HISTOPATHOLOGY; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOPEROXIDASE STAINING; MALE; MESANGIUM; MICROALBUMINURIA; MICROSCOPY; MOUSE; MOUSE STRAIN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; URINALYSIS;

ANIMALS; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; GLYCOSYLATION END PRODUCTS, ADVANCED; KIDNEY GLOMERULUS; MALE; MICE; MICE, INBRED BALB C; TRANSFORMING GROWTH FACTOR BETA;

EID: 33645361420     PISSN: 13205358     EISSN: 14401797     Source Type: Journal    
DOI: 10.1111/j.1440-1797.2006.00543.x     Document Type: Article

References (28)

1. Makino S Kunimoto K Muraoka Y Mizushima Y Katagiri K Tochino Y Breeding of a non-obese, diabetic strain of mice Jikken Dobutsu 1980 29 1 13
2. Yoshioka M Kayo T Ikeda T Koizumi A A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL6 (Akita) mutant mice Diabetes 1997 46 887 94
3. Hummel KP Dickie MM Coleman DL Diabetes, a new mutation in the mouse Science 1966 153 1127 8
4. Hummel KP Coleman DL Lane PW The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL-KsJ and C57BL-6J strains BiochemGenet 1972 7 1 13
5. Ueda H Ikegami H Yamato E et al. The NSY mouse: A new animal model of spontaneous NIDDM with moderate obesity Diabetologia 1995 38 503 8
6. Suzuki W Iizuka S Tabuchi M et al. A new mouse model of spontaneous diabetes derived from ddY strain ExpAnim 1999 48 181 9
7. Kondo K Nozawa K Tomita T Ezaki K Inbred strains resulting from Japanese mice BullExpAnim 1957 6 107 12
8. Sharma K McCue P Dunn SR Diabetic kidney disease in the db/db mouse AmJPhysiolRenal Physiol 2003 284 F1138 44 Review.
9. Chen H Charlat O Tartaglia LA et al. Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice Cell 1996 84 491 5
10. Lee GH Proenca R Montez JM et al. Abnormal splicing of the leptin receptor in diabetic mice Nature 1996 379 632 5
11. Taketomi S Ikeda H Ishikawa E Iwatsuka H Determination of overall insulin sensitivity in diabetic mice, KK HormMetabRes 1982 14 14 18
12. Matsuo T Shino A Induction of diabetic alterations by gold thioglucose-obesity in KK, ICR and C57BL mice Diabetologia 1972 8 391 7
13. Ikeda H KK mouse Diabetes ResClinPract 1994 Suppl. 24 S313 16
14. Wehner H Hohn D Faix-Scheade U Huber H Walzer P Glomerular changes in mice with spontaneous hereditary diabetes LabInvest 1972 27 331 40
15. Duhault J Lebon F Boulanger M KK mice as a model of microangiopathic lesions in diabetes BiblAnat 1973 11 453 8
16. y mice ExpAnim 2002 51 191 6
17. Nishimura M Breeding of mice strains for diabetes mellitus ExpAnim 1969 18 147 57
18. Cohen MP Ziyadeh FN Role of Amadori-modified nonenzymatically glycated serum proteins in the pathogenesis of diabetic nephropathy JAmSocNephrol 1996 7 183 90 Review.
19. Fukami K Ueda S Yamagishi S et al. AGEs activate mesangial TGF-beta-Smad signaling via an angiotensin II type I receptor interaction Kidney Int 2004 66 2137 47
20. Bierhaus A Hofmann MA Ziegler R Nawroth PP AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept CardiovascRes 1998 37 586 600 Review.
21. Nishimoto Y Tomida T Matsui H Ito T Okumura K Decrease in renal medullary endothelial nitric oxide synthase of fructose-fed, salt-sensitive hypertensive rats Hypertension 2002 40 190 94
22. Aizawa-Abe M Ogawa Y Masuzaki H et al. Pathophysiological role of leptin in obesity-related hypertension JClinInvest 2000 105 1243 52
23. Liao J Kobayashi M Kanamuru Y et al. Effects of candesartan, an angiotensin II type 1 receptor blocker, on diabetic nephropathy in KK/Ta mice JNephrol 2003 16 841 9
24. Cohen MP Lautenslager GT Shearman CW Increased urinary type IV collagen marks the development of glomerular pathology in diabetic db/db mice Metabolism 2001 50 1435 40
25. Ha TS Barnes JL Stewart JL et al. Regulation of renal laminin in mice with type II diabetes JAmSocNephrol 1999 10 1931 9
26. UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes. UKPDS 38 BMJ 1998 317 703 13
27. Komers R Lindsley JN Oyama TT Allison KM Anderson S Role of neuronal nitric oxide synthase (NOS1) in the pathogenesis of renal hemodynamic changes in diabetes AmJPhysiolRenal Physiol 2000 279 F573 83
28. Soulis-Liparota T Cooper M Papazoglou D Clarke B Jerums G Retardation by aminoguanidine of development of albuminuria, mesangial expansion, and tissue fluorescence in streptozocin-induced diabetic rat Diabetes 1991 40 1328 34