Discovery of novel 2-hydroxydiarylamide derivatives as TMPRSS4 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 6, 2013, Pages 1748-1751

  Kang, Sunghyun ^a   Min, Hye Jin ^a   Kang, Min Seo ^b   Jung, Myung Geun ^b   Kim, Semi ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

2 Hydroxydiarylamide; Antitumor; Invasion; TMPRSS4 inhibitors

Indexed keywords

AROMATIC AMIDE; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL INVASION; COLON CANCER; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVITY; METASTASIS;

AMIDES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; COLONIC NEOPLASMS; DRUG EVALUATION, PRECLINICAL; HUMANS; MEMBRANE PROTEINS; PROTEIN BINDING; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84874667608     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.01.055     Document Type: Article

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