Ethanol and vitamin D receptor in T cell apoptosis

Journal of Neuroimmune Pharmacology

Volumn 8, Issue 1, 2013, Pages 251-261

  Rehman, Shabina ^a   Chandel, Nirupama ^a   Salhan, Divya ^a   Rai, Partab ^a   Sharma, Bipin ^a   Singh, Tejinder ^a   Husain, Mohammad ^a   Malhotra, Ashwani ^a   Singhal, Pravin C ^a  

^a DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

Author keywords

Active vitamin D; Angiotensin II; Apoptosis; AT1 receptor blocker; Catalase; DNA damage; DNA repair; Losartan; Reactive oxygen species; Renin; T cells, vitamin D receptor; Tempol

Indexed keywords

ALCOHOL; ANGIOTENSIN II; CATALASE; LOSARTAN; REACTIVE OXYGEN METABOLITE; RENIN; TEMPOL; VITAMIN D RECEPTOR;

APOPTOSIS; ARTICLE; DNA DAMAGE; DNA REPAIR; DOWN REGULATION; HUMAN; LEUKEMIA CELL LINE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; T LYMPHOCYTE;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANNEXIN A5; APOPTOSIS; BLOTTING, WESTERN; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; ENZYME-LINKED IMMUNOSORBENT ASSAY; ETHANOL; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IN SITU NICK-END LABELING; JURKAT CELLS; KINETICS; LOSARTAN; REACTIVE OXYGEN SPECIES; RECEPTORS, CALCITRIOL; RENIN-ANGIOTENSIN SYSTEM; T-LYMPHOCYTES;

EID: 84874645683     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-012-9393-9     Document Type: Article

References (64)

1. Adams HG, Jordan C (1984) Infections in the alcoholic. Med Clin North Am 68:179-200
2. MacGregor RR (1986) Alcohol and immune defense. JAMA 256:1474-1479
3. Young CL, MacGregor RR (1980) Alcohol and host defenses: infectious consequences. Infect Med 6:163-75
4. Capps JA, Coleman GH (1923) Influence of alcohol on prognosis of pneumonia in Cook County Hospital: a statistical report. JAMA 80:750-2
5. Young GP, Van der Weyden MB, Ros IS, Dudley FJ (1979) Lymphopenia and lymphocyte transformation in alcoholics. Experientia 35:268-269
6. Roselle GA, Mendenhall CL, Grossman CJ, Weesner RE (1988) Lymphocyte subset alterations in patients with alcoholic hepatitis. J Clin Lab Immunol 26:169-173
7. + cell count after alcohol withdrawal in HIV-positive alcoholic patients. AIDS 10:1293-1294
8. Laso FJ, Madruga JI, Lopez A, Ciudad J, Alvarez-Mon M, San Miguel J (1996) Distribution of peripheral blood lymphoid subsets in alcoholic liver cirrhosis: influence of ethanol intake. Alcohol Clin Exp Res 20:1564-1568
9. Gheorghiu M, Bara C, Pasarica D, Brasoveanu L, Bleotu C, Toparceanu F (2004) Ethanol-induced dysfunction of hepatocytes and leukocytes in patients without liver failure. Roum Arch Microbiol Immunol 63:5-33
10. Kazbariene B, Krikstaponiene A, Monceviciute-Eringiene E (2006) Disturbance of human immunohomeostasis by environmental pollution and alcohol consumption. Acta Microbiol Immunol Hung 53:209-218
11. Helm RM, Wheeler G, Burks AW, Hakkak R, Badger TM (1996) Flow cytometric analysis of lymphocytes from rats following chronic ethanol treatment. Alcohol 13:467-471
12. Chadha KC, Stadler I, Albini B, Nakeeb SM, Thacore HR (1991) Effect of alcohol on spleen cells and their functions in C57BL/6 mice. Alcohol 8:481-485
13. Shellito JE, Olariu R (1998) Alcohol decreases T-lymphocyte migration into lung tissue in response to Pneumocystis carinii and depletes T-lymphocyte numbers in the spleens of mice. Alcohol Clin Exp Res 22:658-663
14. Peterson JD, Herzenberg LA, Vasquez K, Waltenbaugh C (1998) Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns. Proc Natl Acad Sci U S A 17:3071-3076
15. Saad AJ, Jerrells TR (1991) Flow cytometric and immunohistochemical evaluation of ethanol-induced changes in splenic and thymic lymphoid cell populations. Alcohol Clin Exp Res 15:796-803
16. Jerrells TR, Saad AJ, Domiati-Saad R (1992) Effects of ethanol on parameters of cellular immunity and host defense mechanisms to infectious agents. Alcohol 9:459-463
17. Padgett EL, Sibley DA, Jerrells TR (2000) Effect of adrenalectomy on ethanol-associated changes in lymphocyte cell numbers and subpopulations in thymus, spleen, and gut-associated lymphoid tissues. Int J Immunopharmacol 22:285-298
18. Louria DB (1963) Susceptibility to infection during experimental alcohol intoxication. Trans Assoc Am Physicians 76:102-10
19. Liu YK (1973) Leukopenia in alcoholics. Am J Med 54:605-10
20. Kumar H, Kawai T, Akira S (2011) Pathogen recognition by the innate immune system. Int Rev Immunol 30:16-34
21. Lindenbaum J, Hargrove L (1968) Thrombocytopenia in alcoholics. Ann Intern Med 68:526-32
22. McFarland W, Libre EP (1963) Abnormal leukocyte response in alcoholism. Ann Intern Med 59:865-77
23. Kapasi AA, Patel G, Goenka A, Nahar N, Modi N, Bhaskaran M, Reddy K, Franki N, Patel J, Singhal PC (2003) Ethanol promotes T cell apoptosis through the mitochondrial pathway. Immunology 108:313-20
24. von Essen MR, Kongsbak M, Schjerling P, Olgaard K, Odum N, Geisler C (2010) Vitamin D controls T cell antigen receptor signaling and activation of human T cells. Nat Immunol 11:344-9
25. Irvin BJ, Williams BL, Nilson AE, Maynor HO, Abraham RT (2000) Pleiotropic contributions of phospholipase C-γ1 (PLC-γ1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-γ1-deficient Jurkat T-cell line. Mol Cell Biol 20:9149-9161
26. Christakos S, Dhawan P, Benn B, Porta A, Hediger M, Oh GT, Jeung EB, Zhong Y, Ajibade D, Dhawan K, Joshi S (2007) Vitamin D: molecular mechanism of action. Ann N Y Acad Sci 1116:340-8
27. White JH (2012) Vitamin D metabolism and signaling in the immune system. Rev Endocr Metab Disord 13:21-9
28. Costa EM, Feldman D (1987) Measurement of 1,25-dihydroxyvitamin D3 receptor turnover by dense amino acid labeling: changes during receptor up-regulation by vitamin D metabolites. Endocrinology 120:1173-1178
29. Li YC, Kong J, Wei M, Chen ZF, Liu SQ, Cao LP (2002) 1,25- Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest 110:229-38
30. Li YC, Qiao G, Uskokovic M, Xiang W, Zheng W, Kong J (2004) Vitamin D: a negative endocrine regulator of the renin-angiotensin system and blood pressure. J Steroid Biochem Mol Biol 89-90:387-92
31. 3-induced growth inhibition. J Biol Chem 277:25884-25892
32. Husain M, Meggs LG, Vashistha H, Simoes S, Griffiths KO, Kumar D, Mikulak J, Mathieson PW, Saleem MA, Del Valle L, Pina-Oviedo S, Wang JY, Seshan SV, Malhotra A, Reiss K, Singhal PC (2009) Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis. J Biol Chem 284:16648-58
33. Salhan D, Pathak S, Husain M, Tandon P, Kumar D, Malhotra A, Meggs LG, Singhal PC (2012) HIV gene expression deactivates redox-sensitive stress response program in mouse tubular cells both in vitro and in vivo. Am J Physiol Renal Physiol 302(1):F129-40
34. Hoch NE, Guzik TJ, Chen W, Deans T, Maalouf SA, Gratze P, Weyand C, Harrison DG (2009) Regulation of T-cell function by endogenously produced angiotensin II. Am J Physiol Regul Integr Comp Physiol 296:R208-R216
35. Knecht KT, Adachi Y, Bradford BU, Iimuro Y, Kadiiska M, Xuang QH, Thurman RG (1995) Free radical adducts in the bile of rats treated chronically with intragastric alcohol. Mol Pharmacol 47:1028-1034
36. Tsukamoto H, Lu SC (2001) Current concepts in the pathogenesis of alcoholic liver injury. FASEB J 15:1335-1349
37. Iimuro Y, Bradford BU, Yamashina S, Rusyn I, Nakagami M, Enomoto N, Kono H, Frey W, Forman D, Brenner D, Thurman RG (2000) The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat. Hepatology 31:391-398
38. Nanji AA, Zhao S, Sadrzadeh SM, Dannenberg AJ, Tahan SR, Waxman DJ (1994) Markedly enhanced cytochrome P450 2E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-treated ethanol-fed rats. Alcohol Clin Exp Res 18(1280-1285):1994
39. Morimoto M, Zern MA, Hagbjörk AL, Ingelman-Sundberg M, French SW (1994) Fish oil, alcohol, and liver pathology: Role of cytochrome P450 2E1. Proc Soc Exp Biol Med 207:197-205
40. Tsukamoto H, Horne W, Kamimura S, Niemelä O, Parkkila S, Ylä-Herttuala S, Brittenham GM (1995) Experimental liver cirrhosis induced by alcohol and iron. J Clin Invest 96:620-630
41. Adachi M, Ishii H (2002) Role of mitochondria in alcoholic liver injury. Free Radic Biol Med 32:487-491
42. Bailey SM, Cunningham CC (2002) Contribution of mitochondria to oxidative stress associated with alcoholic liver disease. Free Radic Biol Med 32:11-16
43. Boveris A, Chance B (1973) The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134:707-716
44. Boveris A, Cadenas E (1975) Mitochondrial production of superoxide anions and its relationship to the antimycin insensitive respiration. FEBS Lett 54:311-314
45. Chiaramonte R, Bartolini E, Riso P, Calzavara E, Erba D, Testolin G, Comi P, Sherbet GV (2001) Oxidative stress signalling in the apoptosis of Jurkat T-Lymphocytes. J Cell Biochem 82:437-444
46. de Cavanagh EM, Piotrkowski B, Basso N, Stella I, Inserra F, Ferder L, Fraga CG (2003) Enalapril and losartan attenuate mitochondrial dysfunction in aged rats. FASEB J 17:1096-1098
47. de Cavanagh EM, Toblli JE, Ferder L, Piotrkowski B, Stella I, Inserra F (2006) Renal mitochondrial dysfunction in spontaneously hypertensive rats is attenuated by losartan but not by amlodipine. Am J Physiol Regul Integr Comp Physiol 290:R1616-R1625
48. Monteiro P, Duarte AI, Goncalves LM, Providencia LA (2005) Valsartan improves mitochondrial function in hearts submitted to acute ischemia. Eur J Pharmacol 518:158-164
49. Kimura S, Zhang GX, Nishiyama A, Shokoji T, Yao L, Fan YY, Rahman M, Abe Y (2005) Mitochondria-derived reactive oxygen species and vascular MAP kinases: comparison of angiotensin II and diazoxide. Hypertension 45:438-444
50. Ide T, Tsutsui H, Hayashidani S, Kang D, Suematsu N, Nakamura K, Utsumi H, Hamasaki N, Takeshita A (2001) Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction. Circ Res 88:529-535
51. Iuchi T, Akaike M, Mitsui T, Ohshima Y, Shintani Y, Azuma H, Matsumoto T (2003) Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction. Circ Res 92:81-87
52. Doughan AK, Harrison DG, Dikalov SI (2008) Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ Res 102(4):488-96
53. Fuertesa MA, Castillab J, Alonsoa C, Perez JM (2003) Cisplatin biochemical mechanism of action: from cytotoxicity to induction of cell death through interconnections between apoptotic and necrotic pathways. Curr Med Chem 10:257-266
54. Lee J, Giordano S, Zhang J (2012) Autophagy, mitochondria and oxidative stress: cross-talk and redox signaling. Biochem J 441:523-540
55. Brigelius-Flohé R, Flohé L (2011) Basic principles and emerging concepts in the redox control of transcription factors. Antioxid Redox Signal 15:2335-2381
56. Suen D-F, Norris KL, Youle RJ (2008) Mitochondrial dynamics and apoptosis. Genes Dev 22:1577-1590
57. Galluzzi L, Morselli E, Vicencio JM, Kepp O, Joza N, Tajeddine N, Kroemer G (2008) Life, death and burial: multifaceted impact of autophagy. Biochem Soc Trans 36:786-90
58. Gozuacik D, Kimchi A (2007) Autophagy and cell death. Curr Top Dev Biol 78:217-245
59. Meijer AJ, Codogno P (2004) Regulation and role of autophagy in mammalian cells. Int J Biochem Cell Biol 36:2445-2462
60. Mizushima N (2007) Autophagy: process and function. Genes Dev 21:2861-2873
61. Baehrecke EH (2005) Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 6:505-510
62. Yadav A, Vallabu S, Arora S, Tandon P, Slahan D, Teichberg S, Singhal PC (2010) Ang II promotes autophagy in podocytes. Am J Physiol Cell Physiol 299:C488-96
63. von Haefen C, Sifringer M, Menk M, Spies CD (2011) Ethanol enhances susceptibility to apoptotic cell death via down-regulation of autophagy-related proteins. Alcohol Clin Exp Res 35:1381-91
64. Yuk JM, Shin DM, Lee HM, Yang CS, Jin HS, Kim KK, Lee ZW, Lee SH, Kim JM, Jo EK (2009) Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin. Cell Host Microbe 6:231-43