Candida albicans morphogenesis is not required for macrophage interleukin 1β production

mBio

Volumn 4, Issue 1, 2013, Pages

  Wellington, Melanie ^a   Koselny, Kristy ^a   Krysan, Damian J ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CANDIDA ALBICANS; CELL INTERACTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOLYSIS; DELETION MUTANT; FUNGAL DEVELOPMENT; FUNGAL STRUCTURES; FUNGUS HYPHAE; MACROPHAGE; MACROPHAGE ACTIVATION; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECIES COMPARISON; WILD TYPE; ANIMAL; CELL LINE; GENE DELETION; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; MICROBIOLOGY; PATHOGENICITY; SECRETION (PROCESS);

ANIMALS; CANDIDA ALBICANS; CELL LINE; GENE DELETION; HYPHAE; INTERLEUKIN-1BETA; MACROPHAGES; MICE; TRANSCRIPTION FACTORS;

EID: 84874643221     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00433-12     Document Type: Article

References (22)

1. Moran GP, Coleman D, Sullivan D. 2012. An introduction to the medically important Candida species, p. 11-25. In Calderone R, Clancy CJ (ed.), Candida and candidiasis, 2nd ed. ASM Press, Washington, DC.
2. Cheng SC, Joosten LA, Kullberg BJ, Netea MG. 2012. Interplay between Candida albicans and the mammalian innate host defense. Infect. Immun. 80:1304-1313.
3. Whiteway M, Oberholzer U. 2004. Candida morphogenesis and hostpathogen interactions. Curr. Opin. Microbiol. 7:350-357.
4. Noble SM, French S, Kohn LA, Chen V, Johnson AD. 2010. Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity. Nat. Genet. 42:590-598.
5. Joly S, et al. 2009. Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome. J. Immunol. 183:3578-3581.
6. Cheng SC, et al. 2011. The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans. J. Leukoc. Biol. 90: 357-366.
7. Hise AG, et al. 2009. An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans. Cell Host Microbe 5:487-497.
8. Vonk AG, et al. 2006. Endogenous interleukin (IL)-1 alpha and IL-1 beta are crucial for host defense against disseminated candidiasis. J. Infect. Dis. 193:1419-1426.
9. Franchi L, Muñoz-Planillo R, Núñez G. 2012. Sensing and reacting to microbes through the inflammasomes. Nat. Immunol. 13:325-332.
10. van de Veerdonk FL, et al. 2009. Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans. J. Infect. Dis. 199:1087-1096.
11. Gross O, et al. 2009. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 459:433-436.
12. Gringhuis SI, et al. 2012. Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome. Nat. Immunol. 13:246-254.
13. Lewis LE, et al. 2012. Stage specific assessment of Candida albicans phagocytosis by macrophages identifies cell wall composition and morphogenesis as key determinants. PLoS Pathog. 8:e1002578.
14. Pietrella D, et al. 2010. The inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity. Infect. Immun. 78:4754-4762.
15. Ghosh S, et al. 2010. Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line. FEMS Immunol. Med. Microbiol. 60:63-73.
16. Homann OR, Dea J, Noble SM, Johnson AD. 2009. A phenotypic profile of the Candida albicans regulatory network. PLoS Genet. 5:e1000783.
17. McKenzie CG, et al. 2010. Contribution of Candida albicans cell wall components to recognition by and escape from murine macrophages. Infect. Immun. 78:1650-1658.
18. Vázquez-Torres A, Balish E. 1997. Macrophages in resistance to candidiasis. Microbiol. Mol. Biol. Rev. 61:170-192.
19. Piccini A, et al. 2008. ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way. Proc. Natl. Acad. Sci. U. S. A. 105:8067-8072.
20. Nobile CJ, et al. 2012. A recently evolved transcriptional network controls biofilm development in Candida albicans. Cell 148:126-138.
21. Bergsbaken T, Fink SL, Cookson BT. 2009. Pyroptosis: host cell death and inflammation. Nat. Rev. Microbiol. 7:99-109.
22. Miao EA, Rajan JV, Aderem A. 2011. Caspase-1-induced pyroptotic cell death. Immunol. Rev. 243:206-214.