Effect of cationic cyclopeptides on transdermal and transmembrane delivery of insulin

Molecular Pharmaceutics

Volumn 10, Issue 3, 2013, Pages 951-957

  Chang, Mingming ^a   Li, Xiaohui ^a   Sun, Yuming ^a   Cheng, Fang ^a   Wang, Qing ^a   Xie, Xiaohuan ^a   Zhao, Weijie ^a   Tian, Xin ^b  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Caco 2 cells; cyclopeptide; enhancement activity; insulin; transdermal

Indexed keywords

ARGININE; CYCLOPEPTIDE; GLUCOSE; INSULIN; LYSINE;

ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN CACO 2; DRUG ABSORPTION; DRUG PENETRATION; GLUCOSE BLOOD LEVEL; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN PERMEABILITY; STREPTOZOCIN DIABETES; STRUCTURE ACTIVITY RELATION; TRANSDERMAL DRUG ADMINISTRATION;

EID: 84874639379     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300667p     Document Type: Article

References (34)

1. Shaikh, I. M.; Jadhav, K. R.; Ganga, S.; Kadam, V. J.; Pisal, S. S. Advanced approaches in insulin delivery Curr. Pharm. Biotechnol. 2005, 6 (5) 387-95
2. Huang, Y. Y.; Wang, C. H. Pulmonary delivery of insulin by liposomal carriers J. Controlled Release 2006, 113 (1) 9-14
3. Li, Y. Z.; Quan, Y. S.; Zang, L.; Jin, M. N.; Kamiyama, F.; Katsumi, H.; Yamamoto, A.; Tsutsumi, S. Transdermal delivery of insulin using trypsin as a biochemical enhancer Biol. Pharm. Bull. 2008, 31 (8) 1574-9
4. Mitragotri, S.; Blankschtein, D.; Langer, R. Ultrasound-mediated transdermal protein delivery Science 1995, 269 (5225) 850-3
5. Kanikkannan, N.; Singh, J.; Ramarao, P. Transdermal iontophoretic delivery of bovine insulin and monomeric human insulin analogue J. Controlled Release 1999, 59 (1) 99-105
6. Boucaud, A.; Garrigue, M. A.; Machet, L.; Vaillant, L.; Patat, F. Effect of sonication parameters on transdermal delivery of insulin to hairless rats J. Controlled Release 2002, 81 (1-2) 113-9
7. Sen, A.; Daly, M. E.; Hui, S. W. Transdermal insulin delivery using lipid enhanced electroporation Biochim. Biophys. Acta 2002, 1564 (1) 5-8
8. Zhou, C. P.; Liu, Y. L.; Wang, H. L.; Zhang, P. X.; Zhang, J. L. Transdermal delivery of insulin using microneedle rollers in vivo Int. J. Pharmaceutics 2010, 392 (1-2) 127-33
9. Chen, Y.; Shen, Y.; Guo, X.; Zhang, C.; Yang, W.; Ma, M.; Liu, S.; Zhang, M.; Wen, L. P. Transdermal protein delivery by a coadministered peptide identified via phage display Nat. Biotechnol. 2006, 24 (4) 455-60
10. Hou, Y. W.; Chan, M. H.; Hsu, H. R.; Liu, B. R.; Chen, C. P.; Chen, H. H.; Lee, H. J. Transdermal delivery of proteins mediated by non-covalently associated arginine-rich intracellular delivery peptides Exp. Dermatol. 2007, 16 (12) 999-1006
11. Derossi, D.; Joliot, A. H.; Chassaing, G.; Prochiantz, A. The third helix of the Antennapedia homeodomain translocates through biological membranes J. Biol. Chem. 1994, 269 (14) 10444-50
12. Brooks, H.; Lebleu, B.; Vives, E. Tat peptide-mediated cellular delivery: back to basics Adv. Drug Delivery Rev. 2005, 57 (4) 559-77
13. Hallbrink, M.; Floren, A.; Elmquist, A.; Pooga, M.; Bartfai, T.; Langel, U. Cargo delivery kinetics of cell-penetrating peptides Biochim. Biophys. Acta 2001, 1515 (2) 101-9
14. Futaki, S.; Suzuki, T.; Ohashi, W.; Yagami, T.; Tanaka, S.; Ueda, K.; Sugiura, Y. Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery J. Biol. Chem. 2001, 276 (8) 5836-40
15. Lopes, L. B.; Brophy, C. M.; Furnish, E.; Flynn, C. R.; Sparks, O.; Komalavilas, P.; Joshi, L.; Panitch, A.; Bentley, M. V. Comparative study of the skin penetration of protein transduction domains and a conjugated peptide Pharm. Res. 2005, 22 (5) 750-7
16. Patel, L. N.; Wang, J.; Kim, K. J.; Borok, Z.; Crandall, E. D.; Shen, W. C. Conjugation with cationic cell-penetrating peptide increases pulmonary absorption of insulin Mol. Pharmaceutics 2009, 6 (2) 492-503
17. Beerens, A. M.; Al Hadithy, A. F.; Rots, M. G.; Haisma, H. J. Protein transduction domains and their utility in gene therapy Curr. Gene Ther. 2003, 3 (5) 486-94
18. Ohtake, K.; Natsume, H.; Ueda, H.; Morimoto, Y. Analysis of transient and reversible effects of poly-L-arginine on the in vivo nasal absorption of FITC-dextran in rats J. Controlled Release 2002, 82 (2-3) 263-75
19. Artursson, P.; Lindmark, T.; Davis, S. S.; Illum, L. Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2) Pharm. Res. 1994, 11 (9) 1358-61
20. Zhang, T.; Qu, H.; Li, X.; Zhao, B.; Zhou, J.; Li, Q.; Sun, M. Transmembrane delivery and biological effect of human growth hormone via a phage displayed peptide in vivo and in vitro J. Pharm. Sci. 2010, 99 (12) 4880-91
21. Hsu, T.; Mitragotri, S. Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer Proc. Natl. Acad. Sci. U.S.A. 2011, 108 (38) 15816-21
22. Carmichael, N. M.; Dostrovsky, J. O.; Charlton, M. P. Peptide-mediated transdermal delivery of botulinum neurotoxin type A reduces neurogenic inflammation in the skin Pain 2010, 149 (2) 316-24
23. Prausnitz, M. R. A peptide chaperone for transdermal drug delivery Nat. Biotechnol. 2006, 24 (4) 416-7
24. Torres-Lugo, M.; Garcia, M.; Record, R.; Peppas, N. A. pH-Sensitive hydrogels as gastrointestinal tract absorption enhancers: transport mechanisms of salmon calcitonin and other model molecules using the Caco-2 cell model Biotechnol. Prog. 2002, 18 (3) 612-6
25. Morita, K.; Miyachi, Y. Tight junctions in the skin J. Dermatol. Sci. 2003, 31 (2) 81-9
26. Grice, J. E.; Cross, S. E.; Brownlie, C.; Roberts, M. S. The application of molecular structural predictors of intestinal absorption to screening of compounds for transdermal penetration J. Pharm. Pharmacol. 2010, 62 (6) 750-5
27. Gyurosiova, L.; Laitinen, L.; Raiman, J.; Cizmarik, J.; Sedlarova, E.; Hirvonen, J. Permeability profiles of M-alkoxysubstituted pyrrolidinoethylesters of phenylcarbamic acid across caco-2 monolayers and human skin Pharm. Res. 2002, 19 (2) 162-8
28. Merrifield, B. Solid phase synthesis Science 1986, 232 (4748) 341-7
29. Todo, H.; Kimura, E.; Yasuno, H.; Tokudome, Y.; Hashimoto, F.; Ikarashi, Y.; Sugibayashi, K. Permeation pathway of macromolecules and nanospheres through skin Biol. Pharm. Bull. 2010, 33 (8) 1394-9
30. Matsuzaki, K.; Murase, O.; Fujii, N.; Miyajima, K. Translocation of a channel-forming antimicrobial peptide, magainin 2, across lipid bilayers by forming a pore Biochemistry 1995, 34 (19) 6521-6
31. He, W.; Guo, X.; Xiao, L.; Feng, M. Study on the mechanisms of chitosan and its derivatives used as transdermal penetration enhancers Int. J. Pharmaceutics 2009, 382 (1-2) 234-43
32. Abla, N.; Naik, A.; Guy, R. H.; Kalia, Y. N. Effect of charge and molecular weight on transdermal peptide delivery by iontophoresis Pharm. Res. 2005, 22 (12) 2069-78
33. Shah, P.; Jogani, V.; Bagchi, T.; Misra, A. Role of Caco-2 cell monolayers in prediction of intestinal drug absorption Biotechnol. Prog. 2006, 22 (1) 186-98
34. Ming, X.; Thakker, D. R. Role of basolateral efflux transporter MRP4 in the intestinal absorption of the antiviral drug adefovir dipivoxil Biochem. Pharmacol. 2010, 79 (3) 455-62