Permeability profiles of m-alkoxysubstituted pyrrolidinoethylesters of phenylcarbamic acid across Caco-2 monolayers and human skin

Pharmaceutical Research

Volumn 19, Issue 2, 2002, Pages 162-168

  Gyurosiova L ^a   Laitinen, L ^b   Raiman, J ^b   Imarik J ^a   Sedlarova E ^a   Hirvonen, J ^b  

^a Physics and Informatics   (Slovakia)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Caco 2; Drug permeability; Human skin; Lipophilicity; Phenyl carbamic acid esters

Indexed keywords

CARBAMIC ACID DERIVATIVE; CARBANILIC ACID; LOCAL ANESTHETIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CELL DAMAGE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG DIFFUSION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG STRUCTURE; ELECTRIC CURRENT; HUMAN; HUMAN CELL; IONTOPHORESIS; LIPOPHILICITY; MOLECULAR WEIGHT; MONOLAYER CULTURE; PRIORITY JOURNAL; SKIN; SMALL INTESTINE;

ADMINISTRATION, CUTANEOUS; ALGORITHMS; CACO-2 CELLS; CARBAMATES; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESTERS; HUMANS; IONTOPHORESIS; MOLECULAR WEIGHT; PERMEABILITY; SKIN ABSORPTION; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLIUM SALTS; THIAZOLES;

EID: 0036179689     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1014208515545     Document Type: Article

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