-
1
-
-
0031937494
-
The fight of viruses against apoptosis
-
Tschopp J, Thome M, Hofmann K, Meinl E, (1998) The fight of viruses against apoptosis. Curr Opin Genet Dev 8: 82-87.
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 82-87
-
-
Tschopp, J.1
Thome, M.2
Hofmann, K.3
Meinl, E.4
-
2
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D, Weinberg RA, (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
33750604789
-
Can't kick that oncogene habit
-
Evan GI, (2006) Can't kick that oncogene habit. Cancer Cell 10: 345-347.
-
(2006)
Cancer Cell
, vol.10
, pp. 345-347
-
-
Evan, G.I.1
-
4
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA, (2001) Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413: 732-738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
5
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, et al. (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441: 101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
-
6
-
-
33750976374
-
5′-Triphosphate RNA is the ligand for RIG-I
-
Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, et al. (2006) 5′-Triphosphate RNA is the ligand for RIG-I. Science 314: 994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzozka, K.4
Jung, A.5
-
7
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates
-
Pichlmair A, Schulz O, Tan CP, Naslund TI, Liljestrom P, et al. (2006) RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 314: 997-1001.
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Naslund, T.I.4
Liljestrom, P.5
-
8
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, et al. (2005) Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437: 1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
-
9
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai T, Takahashi K, Sato S, Coban C, Kumar H, et al. (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 6: 981-988.
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
-
10
-
-
79956314622
-
Immune signaling by RIG-I-like receptors
-
Loo YM, Gale M Jr, (2011) Immune signaling by RIG-I-like receptors. Immunity 34: 680-692.
-
(2011)
Immunity
, vol.34
, pp. 680-692
-
-
Loo, Y.M.1
Gale Jr., M.2
-
11
-
-
68849096790
-
Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells
-
Besch R, Poeck H, Hohenauer T, Senft D, Hacker G, et al. (2009) Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells. J Clin Invest 119: 2399-2411.
-
(2009)
J Clin Invest
, vol.119
, pp. 2399-2411
-
-
Besch, R.1
Poeck, H.2
Hohenauer, T.3
Senft, D.4
Hacker, G.5
-
12
-
-
79952857824
-
The IRF-3/Bax-mediated apoptotic pathway, activated by viral cytoplasmic RNA and DNA, inhibits virus replication
-
Chattopadhyay S, Yamashita M, Zhang Y, Sen GC, (2011) The IRF-3/Bax-mediated apoptotic pathway, activated by viral cytoplasmic RNA and DNA, inhibits virus replication. J Virol 85: 3708-3716.
-
(2011)
J Virol
, vol.85
, pp. 3708-3716
-
-
Chattopadhyay, S.1
Yamashita, M.2
Zhang, Y.3
Sen, G.C.4
-
13
-
-
41149143076
-
IRF-3 activation by Sendai virus infection is required for cellular apoptosis and avoidance of persistence
-
Peters K, Chattopadhyay S, Sen GC, (2008) IRF-3 activation by Sendai virus infection is required for cellular apoptosis and avoidance of persistence. J Virol 82: 3500-3508.
-
(2008)
J Virol
, vol.82
, pp. 3500-3508
-
-
Peters, K.1
Chattopadhyay, S.2
Sen, G.C.3
-
14
-
-
84861805678
-
The molecular pathogenesis of head and neck squamous cell carcinoma
-
Rothenberg SM, Ellisen LW, (2012) The molecular pathogenesis of head and neck squamous cell carcinoma. J Clin Invest 122: 1951-1957.
-
(2012)
J Clin Invest
, vol.122
, pp. 1951-1957
-
-
Rothenberg, S.M.1
Ellisen, L.W.2
-
15
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J, Azarnia N, Shin DM, et al. (2006) Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354: 567-578.
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
-
16
-
-
35548972994
-
Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer
-
Posner MR, Hershock DM, Blajman CR, Mickiewicz E, Winquist E, et al. (2007) Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. N Engl J Med 357: 1705-1715.
-
(2007)
N Engl J Med
, vol.357
, pp. 1705-1715
-
-
Posner, M.R.1
Hershock, D.M.2
Blajman, C.R.3
Mickiewicz, E.4
Winquist, E.5
-
17
-
-
0029908016
-
Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
-
Kohn AD, Summers SA, Birnbaum MJ, Roth RA, (1996) Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J Biol Chem 271: 31372-31378.
-
(1996)
J Biol Chem
, vol.271
, pp. 31372-31378
-
-
Kohn, A.D.1
Summers, S.A.2
Birnbaum, M.J.3
Roth, R.A.4
-
18
-
-
84861332826
-
Up-regulation of enhancer of zeste homolog 2 is associated positively with cyclin D1 overexpression and poor clinical outcome in head and neck squamous cell carcinoma
-
Cao W, Feng Z, Cui Z, Zhang C, Sun Z, et al. (2011) Up-regulation of enhancer of zeste homolog 2 is associated positively with cyclin D1 overexpression and poor clinical outcome in head and neck squamous cell carcinoma. Cancer 118: 2858-2871.
-
(2011)
Cancer
, vol.118
, pp. 2858-2871
-
-
Cao, W.1
Feng, Z.2
Cui, Z.3
Zhang, C.4
Sun, Z.5
-
19
-
-
0036554734
-
Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer
-
Malik SN, Brattain M, Ghosh PM, Troyer DA, Prihoda T, et al. (2002) Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. Clin Cancer Res 8: 1168-1171.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1168-1171
-
-
Malik, S.N.1
Brattain, M.2
Ghosh, P.M.3
Troyer, D.A.4
Prihoda, T.5
-
20
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
Davis BK, Wen H, Ting JP, (2011) The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol 29: 707-735.
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.3
-
21
-
-
70350208780
-
The evolutionary conundrum of pathogen mimicry
-
Elde NC, Malik HS, (2009) The evolutionary conundrum of pathogen mimicry. Nat Rev Microbiol 7: 787-797.
-
(2009)
Nat Rev Microbiol
, vol.7
, pp. 787-797
-
-
Elde, N.C.1
Malik, H.S.2
-
22
-
-
80051917697
-
Cell death-independent functions of granzymes: hit viruses where it hurts
-
van Domselaar R, Bovenschen N (2011) Cell death-independent functions of granzymes: hit viruses where it hurts. Rev Med Virol.
-
(2011)
Rev Med Virol
-
-
van Domselaar, R.1
Bovenschen, N.2
-
23
-
-
2442686585
-
The pivotal role of phosphatidylinositol 3-kinase-Akt signal transduction in virus survival
-
Cooray S, (2004) The pivotal role of phosphatidylinositol 3-kinase-Akt signal transduction in virus survival. J Gen Virol 85: 1065-1076.
-
(2004)
J Gen Virol
, vol.85
, pp. 1065-1076
-
-
Cooray, S.1
-
24
-
-
78651396985
-
Phosphatase PRL-3 is a direct regulatory target of TGFbeta in colon cancer metastasis
-
Jiang Y, Liu XQ, Rajput A, Geng L, Ongchin M, et al. (2011) Phosphatase PRL-3 is a direct regulatory target of TGFbeta in colon cancer metastasis. Cancer Res 71: 234-244.
-
(2011)
Cancer Res
, vol.71
, pp. 234-244
-
-
Jiang, Y.1
Liu, X.Q.2
Rajput, A.3
Geng, L.4
Ongchin, M.5
-
25
-
-
0037423201
-
Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling
-
Dawson CW, Tramountanis G, Eliopoulos AG, Young LS, (2003) Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling. J Biol Chem 278: 3694-3704.
-
(2003)
J Biol Chem
, vol.278
, pp. 3694-3704
-
-
Dawson, C.W.1
Tramountanis, G.2
Eliopoulos, A.G.3
Young, L.S.4
-
26
-
-
0033761806
-
Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway
-
Swart R, Ruf IK, Sample J, Longnecker R, (2000) Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway. J Virol 74: 10838-10845.
-
(2000)
J Virol
, vol.74
, pp. 10838-10845
-
-
Swart, R.1
Ruf, I.K.2
Sample, J.3
Longnecker, R.4
-
27
-
-
33746458854
-
Herpes simplex virus US3 protein kinase regulates virus-induced apoptosis in olfactory and vomeronasal chemosensory neurons in vivo
-
Mori I, Goshima F, Watanabe D, Ito H, Koide N, et al. (2006) Herpes simplex virus US3 protein kinase regulates virus-induced apoptosis in olfactory and vomeronasal chemosensory neurons in vivo. Microbes Infect 8: 1806-1812.
-
(2006)
Microbes Infect
, vol.8
, pp. 1806-1812
-
-
Mori, I.1
Goshima, F.2
Watanabe, D.3
Ito, H.4
Koide, N.5
-
28
-
-
1642430625
-
Functions and mechanisms of action of the adenovirus E3 proteins
-
Lichtenstein DL, Toth K, Doronin K, Tollefson AE, Wold WS, (2004) Functions and mechanisms of action of the adenovirus E3 proteins. Int Rev Immunol 23: 75-111.
-
(2004)
Int Rev Immunol
, vol.23
, pp. 75-111
-
-
Lichtenstein, D.L.1
Toth, K.2
Doronin, K.3
Tollefson, A.E.4
Wold, W.S.5
-
29
-
-
80053002717
-
The heme oxygenase-1 protein is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK pathway and mediates anti-apoptotic signal
-
Banerjee P, Basu A, Datta D, Gasser M, Waaga-Gasser AM, et al. (2011) The heme oxygenase-1 protein is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK pathway and mediates anti-apoptotic signal. J Biol Chem 286: 33580-33590.
-
(2011)
J Biol Chem
, vol.286
, pp. 33580-33590
-
-
Banerjee, P.1
Basu, A.2
Datta, D.3
Gasser, M.4
Waaga-Gasser, A.M.5
-
30
-
-
79953222918
-
The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner
-
Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, et al. (2011) The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner. J Biol Chem 286: 9382-9392.
-
(2011)
J Biol Chem
, vol.286
, pp. 9382-9392
-
-
Kazi, A.1
Sun, J.2
Doi, K.3
Sung, S.S.4
Takahashi, Y.5
-
31
-
-
65349107653
-
E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells
-
Rampias T, Sasaki C, Weinberger P, Psyrri A, (2009) E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells. J Natl Cancer Inst 101: 412-423.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 412-423
-
-
Rampias, T.1
Sasaki, C.2
Weinberger, P.3
Psyrri, A.4
-
33
-
-
55549114663
-
5′-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma
-
Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, et al. (2008) 5′-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma. Nat Med 14: 1256-1263.
-
(2008)
Nat Med
, vol.14
, pp. 1256-1263
-
-
Poeck, H.1
Besch, R.2
Maihoefer, C.3
Renn, M.4
Tormo, D.5
|