-
1
-
-
0035750347
-
Chromosome translocations: dangerous liaisons revisited
-
Rowley JD, (2001) Chromosome translocations: dangerous liaisons revisited. Nat Rev Cancer 1: 245-250.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 245-250
-
-
Rowley, J.D.1
-
2
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, et al. (2005) Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310: 644-648.
-
(2005)
Science
, vol.310
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
-
3
-
-
70350109641
-
ETS gene fusions in prostate cancer
-
Clark JP, Cooper CS, (2009) ETS gene fusions in prostate cancer. Nat Rev Urol 6: 429-439.
-
(2009)
Nat Rev Urol
, vol.6
, pp. 429-439
-
-
Clark, J.P.1
Cooper, C.S.2
-
4
-
-
33645750799
-
TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer
-
Tomlins SA, Mehra R, Rhodes DR, Smith LR, Roulston D, et al. (2006) TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer. Cancer Res 66: 3396-3400.
-
(2006)
Cancer Res
, vol.66
, pp. 3396-3400
-
-
Tomlins, S.A.1
Mehra, R.2
Rhodes, D.R.3
Smith, L.R.4
Roulston, D.5
-
5
-
-
39049150843
-
Role of the TMPRSS2-ERG gene fusion in prostate cancer
-
Tomlins SA, Laxman B, Varambally S, Cao X, Yu J, et al. (2008) Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 10: 177-188.
-
(2008)
Neoplasia
, vol.10
, pp. 177-188
-
-
Tomlins, S.A.1
Laxman, B.2
Varambally, S.3
Cao, X.4
Yu, J.5
-
6
-
-
39049170313
-
Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer
-
Helgeson BE, Tomlins SA, Shah N, Laxman B, Cao Q, et al. (2008) Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer. Cancer Res 68: 73-80.
-
(2008)
Cancer Res
, vol.68
, pp. 73-80
-
-
Helgeson, B.E.1
Tomlins, S.A.2
Shah, N.3
Laxman, B.4
Cao, Q.5
-
7
-
-
66749188650
-
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
-
Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, et al. (2009) Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat Genet 41: 619-624.
-
(2009)
Nat Genet
, vol.41
, pp. 619-624
-
-
Carver, B.S.1
Tran, J.2
Gopalan, A.3
Chen, Z.4
Shaikh, S.5
-
8
-
-
34248510706
-
TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort
-
Demichelis F, Fall K, Perner S, Andren O, Schmidt F, et al. (2007) TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort. Oncogene 26: 4596-4599.
-
(2007)
Oncogene
, vol.26
, pp. 4596-4599
-
-
Demichelis, F.1
Fall, K.2
Perner, S.3
Andren, O.4
Schmidt, F.5
-
9
-
-
33847105565
-
Expression of TMPRSS2:ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression
-
Nam RK, Sugar L, Wang Z, Yang W, Kitching R, et al. (2007) Expression of TMPRSS2:ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression. Cancer Biol Ther 6: 40-45.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 40-45
-
-
Nam, R.K.1
Sugar, L.2
Wang, Z.3
Yang, W.4
Kitching, R.5
-
10
-
-
33749029695
-
TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer
-
Perner S, Demichelis F, Beroukhim R, Schmidt FH, Mosquera JM, et al. (2006) TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer. Cancer Res 66: 8337-8341.
-
(2006)
Cancer Res
, vol.66
, pp. 8337-8341
-
-
Perner, S.1
Demichelis, F.2
Beroukhim, R.3
Schmidt, F.H.4
Mosquera, J.M.5
-
11
-
-
33947590808
-
Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers
-
Rajput AB, Miller MA, De Luca A, Boyd N, Leung S, et al. (2007) Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers. J Clin Pathol 60: 1238-1243.
-
(2007)
J Clin Pathol
, vol.60
, pp. 1238-1243
-
-
Rajput, A.B.1
Miller, M.A.2
De Luca, A.3
Boyd, N.4
Leung, S.5
-
12
-
-
41149097040
-
A causal role for ERG in neoplastic transformation of prostate epithelium
-
Klezovitch O, Risk M, Coleman I, Lucas JM, Null M, et al. (2008) A causal role for ERG in neoplastic transformation of prostate epithelium. Proc Natl Acad Sci U S A 105: 2105-2110.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 2105-2110
-
-
Klezovitch, O.1
Risk, M.2
Coleman, I.3
Lucas, J.M.4
Null, M.5
-
13
-
-
4243110417
-
Pten dose dictates cancer progression in the prostate
-
Trotman LC, Niki M, Dotan ZA, Koutcher JA, Di Cristofano A, et al. (2003) Pten dose dictates cancer progression in the prostate. PLoS Biol 1: E59.
-
(2003)
PLoS Biol
, vol.1
-
-
Trotman, L.C.1
Niki, M.2
Dotan, Z.A.3
Koutcher, J.A.4
Di Cristofano, A.5
-
14
-
-
66749117138
-
TMPRSS2-ERG and PTEN loss in prostate cancer
-
Squire JA, (2009) TMPRSS2-ERG and PTEN loss in prostate cancer. Nat Genet 41: 509-510.
-
(2009)
Nat Genet
, vol.41
, pp. 509-510
-
-
Squire, J.A.1
-
15
-
-
0023220610
-
erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation
-
Rao VN, Papas TS, Reddy ES, (1987) erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation. Science 237: 635-639.
-
(1987)
Science
, vol.237
, pp. 635-639
-
-
Rao, V.N.1
Papas, T.S.2
Reddy, E.S.3
-
16
-
-
0027972534
-
Differentially spliced erg-3 product functions as a transcriptional activator
-
Prasad DD, Rao VN, Lee L, Reddy ES, (1994) Differentially spliced erg-3 product functions as a transcriptional activator. Oncogene 9: 669-673.
-
(1994)
Oncogene
, vol.9
, pp. 669-673
-
-
Prasad, D.D.1
Rao, V.N.2
Lee, L.3
Reddy, E.S.4
-
17
-
-
0027275782
-
New human erg isoforms generated by alternative splicing are transcriptional activators
-
Duterque-Coquillaud M, Niel C, Plaza S, Stehelin D, (1993) New human erg isoforms generated by alternative splicing are transcriptional activators. Oncogene 8: 1865-1873.
-
(1993)
Oncogene
, vol.8
, pp. 1865-1873
-
-
Duterque-Coquillaud, M.1
Niel, C.2
Plaza, S.3
Stehelin, D.4
-
18
-
-
0346789073
-
Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16
-
Owczarek CM, Portbury KJ, Hardy MP, O'Leary DA, Kudoh J, et al. (2004) Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16. Gene 324: 65-77.
-
(2004)
Gene
, vol.324
, pp. 65-77
-
-
Owczarek, C.M.1
Portbury, K.J.2
Hardy, M.P.3
O'Leary, D.A.4
Kudoh, J.5
-
19
-
-
33749034498
-
Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer
-
Wang J, Cai Y, Ren C, Ittmann M, (2006) Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer. Cancer Res 66: 8347-8351.
-
(2006)
Cancer Res
, vol.66
, pp. 8347-8351
-
-
Wang, J.1
Cai, Y.2
Ren, C.3
Ittmann, M.4
-
20
-
-
34247389322
-
Diversity of TMPRSS2-ERG fusion transcripts in the human prostate
-
Clark J, Merson S, Jhavar S, Flohr P, Edwards S, et al. (2007) Diversity of TMPRSS2-ERG fusion transcripts in the human prostate. Oncogene 26: 2667-2673.
-
(2007)
Oncogene
, vol.26
, pp. 2667-2673
-
-
Clark, J.1
Merson, S.2
Jhavar, S.3
Flohr, P.4
Edwards, S.5
-
21
-
-
50549095607
-
Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer
-
FitzGerald LM, Agalliu I, Johnson K, Miller MA, Kwon EM, et al. (2008) Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer. BMC Cancer 8: 230.
-
(2008)
BMC Cancer
, vol.8
, pp. 230
-
-
FitzGerald, L.M.1
Agalliu, I.2
Johnson, K.3
Miller, M.A.4
Kwon, E.M.5
-
22
-
-
38749125174
-
Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays
-
Jhavar S, Reid A, Clark J, Kote-Jarai Z, Christmas T, et al. (2008) Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays. J Mol Diagn 10: 50-57.
-
(2008)
J Mol Diagn
, vol.10
, pp. 50-57
-
-
Jhavar, S.1
Reid, A.2
Clark, J.3
Kote-Jarai, Z.4
Christmas, T.5
-
23
-
-
20444493600
-
Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome
-
Petrovics G, Liu A, Shaheduzzaman S, Furusato B, Sun C, et al. (2005) Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome. Oncogene 24: 3847-3852.
-
(2005)
Oncogene
, vol.24
, pp. 3847-3852
-
-
Petrovics, G.1
Liu, A.2
Shaheduzzaman, S.3
Furusato, B.4
Sun, C.5
-
24
-
-
54249154706
-
Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts
-
Wang J, Cai Y, Yu W, Ren C, Spencer DM, et al. (2008) Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts. Cancer Res 68: 8516-8524.
-
(2008)
Cancer Res
, vol.68
, pp. 8516-8524
-
-
Wang, J.1
Cai, Y.2
Yu, W.3
Ren, C.4
Spencer, D.M.5
-
25
-
-
33947358183
-
Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model
-
Mertz KD, Setlur SR, Dhanasekaran SM, Demichelis F, Perner S, et al. (2007) Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model. Neoplasia 9: 200-206.
-
(2007)
Neoplasia
, vol.9
, pp. 200-206
-
-
Mertz, K.D.1
Setlur, S.R.2
Dhanasekaran, S.M.3
Demichelis, F.4
Perner, S.5
-
26
-
-
51649115957
-
TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation
-
Sun C, Dobi A, Mohamed A, Li H, Thangapazham RL, et al. (2008) TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation. Oncogene 27: 5348-5353.
-
(2008)
Oncogene
, vol.27
, pp. 5348-5353
-
-
Sun, C.1
Dobi, A.2
Mohamed, A.3
Li, H.4
Thangapazham, R.L.5
-
27
-
-
0032775391
-
PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation
-
Ghosh AK, Grigorieva I, Steele R, Hoover RG, Ray RB, (1999) PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation. Gene 235: 85-91.
-
(1999)
Gene
, vol.235
, pp. 85-91
-
-
Ghosh, A.K.1
Grigorieva, I.2
Steele, R.3
Hoover, R.G.4
Ray, R.B.5
-
28
-
-
80051681322
-
TMPRSS2-ERG-mediated feed-forward regulation of wild-type ERG in human prostate cancers
-
Mani RS, Iyer MK, Cao Q, Brenner JC, Wang L, et al. (2011) TMPRSS2-ERG-mediated feed-forward regulation of wild-type ERG in human prostate cancers. Cancer Res 71: 5387-5392.
-
(2011)
Cancer Res
, vol.71
, pp. 5387-5392
-
-
Mani, R.S.1
Iyer, M.K.2
Cao, Q.3
Brenner, J.C.4
Wang, L.5
-
29
-
-
27144555357
-
Regulation of translation via mRNA structure in prokaryotes and eukaryotes
-
Kozak M, (2005) Regulation of translation via mRNA structure in prokaryotes and eukaryotes. Gene 361: 13-37.
-
(2005)
Gene
, vol.361
, pp. 13-37
-
-
Kozak, M.1
-
30
-
-
77957757037
-
Jailbreak: oncogene-induced senescence and its evasion
-
McDuff FK, Turner SD, (2011) Jailbreak: oncogene-induced senescence and its evasion. Cell Signal 23: 6-13.
-
(2011)
Cell Signal
, vol.23
, pp. 6-13
-
-
McDuff, F.K.1
Turner, S.D.2
-
31
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, et al. (2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436: 725-730.
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
Lin, H.K.4
Dotan, Z.A.5
-
32
-
-
0025792297
-
Structural features in eukaryotic mRNAs that modulate the initiation of translation
-
Kozak M, (1991) Structural features in eukaryotic mRNAs that modulate the initiation of translation. J Biol Chem 266: 19867-19870.
-
(1991)
J Biol Chem
, vol.266
, pp. 19867-19870
-
-
Kozak, M.1
-
33
-
-
41449117605
-
uORFs, reinitiation and alternative translation start sites in human mRNAs
-
Kochetov AV, Ahmad S, Ivanisenko V, Volkova OA, Kolchanov NA, et al. (2008) uORFs, reinitiation and alternative translation start sites in human mRNAs. FEBS Lett 582: 1293-1297.
-
(2008)
FEBS Lett
, vol.582
, pp. 1293-1297
-
-
Kochetov, A.V.1
Ahmad, S.2
Ivanisenko, V.3
Volkova, O.A.4
Kolchanov, N.A.5
-
34
-
-
66149118241
-
Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
-
Calvo SE, Pagliarini DJ, Mootha VK, (2009) Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans. Proc Natl Acad Sci U S A 106: 7507-7512.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 7507-7512
-
-
Calvo, S.E.1
Pagliarini, D.J.2
Mootha, V.K.3
-
35
-
-
0030444182
-
Erg, an Ets-family member, differentially regulates human collagenase1 (MMP1) and stromelysin1 (MMP3) gene expression by physically interacting with the Fos/Jun complex
-
Buttice G, Duterque-Coquillaud M, Basuyaux JP, Carrere S, Kurkinen M, et al. (1996) Erg, an Ets-family member, differentially regulates human collagenase1 (MMP1) and stromelysin1 (MMP3) gene expression by physically interacting with the Fos/Jun complex. Oncogene 13: 2297-2306.
-
(1996)
Oncogene
, vol.13
, pp. 2297-2306
-
-
Buttice, G.1
Duterque-Coquillaud, M.2
Basuyaux, J.P.3
Carrere, S.4
Kurkinen, M.5
-
36
-
-
43549123588
-
Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin
-
Birdsey GM, Dryden NH, Amsellem V, Gebhardt F, Sahnan K, et al. (2008) Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin. Blood 111: 3498-3506.
-
(2008)
Blood
, vol.111
, pp. 3498-3506
-
-
Birdsey, G.M.1
Dryden, N.H.2
Amsellem, V.3
Gebhardt, F.4
Sahnan, K.5
-
37
-
-
49949086671
-
Controlling morpholino experiments: don't stop making antisense
-
Eisen JS, Smith JC, (2008) Controlling morpholino experiments: don't stop making antisense. Development 135: 1735-1743.
-
(2008)
Development
, vol.135
, pp. 1735-1743
-
-
Eisen, J.S.1
Smith, J.C.2
-
38
-
-
63449133262
-
Gene knockdowns in adult animals: PPMOs and vivo-morpholinos
-
Moulton JD, Jiang S, (2009) Gene knockdowns in adult animals: PPMOs and vivo-morpholinos. Molecules 14: 1304-1323.
-
(2009)
Molecules
, vol.14
, pp. 1304-1323
-
-
Moulton, J.D.1
Jiang, S.2
|