Novel HldE-K inhibitors leading to attenuated gram negative bacterial virulence

Journal of Medicinal Chemistry

Volumn 56, Issue 4, 2013, Pages 1418-1430

  Desroy, Nicolas ^a,d   Denis, Alexis ^a,e   Oliveira, Chrystelle ^a   Atamanyuk, Dmytro ^a   Briet, Sophia ^a   Faivre, Fabien ^a   Lefralliec, Géraldine ^a   Bonvin, Yannick ^a   Oxoby, Mayalen ^a   Escaich, Sonia ^b,f   Floquet, Stéphanie ^b   Drocourt, Elodie ^b   Vongsouthi, Vanida ^b   Durant, Lionel ^b,g   Moreau, François ^b   Verhey, Theodore B ^c   Lee, Ting Wai ^c   Junop, Murray S ^c   Gerusz, Vincent ^a  

^a Mutabilis   (France)

^b Mutabilis   (France)

^c MCMASTER UNIVERSITY   (Canada)

^d Galapagos SASU   (France)

^e GLAXOSMITHKLINE   (France)

^f ESE Conseil   (France)

^g Alderys   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ERYTHROMYCIN; TRIAZINE DERIVATIVE;

ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BLOODSTREAM INFECTION; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROCESS OPTIMIZATION;

EID: 84874596890     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301499r     Document Type: Article

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