Vaccine pharmacotherapy for the treatment of cocaine dependence

Biological Psychiatry

Volumn 58, Issue 2, 2005, Pages 158-164

  Martell, Bridget A ^a,b   Mitchell, Ellen ^b   Poling, James ^b   Gonsai, Kishor ^a,b   Kosten, Thomas R ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Antibodies; Clinical trials; Cocaine addiction; Drug dependence; Pharmacotherapy; Vaccine

Indexed keywords

ANTIBODY; COCAINE; COCAINE VACCINE; PLACEBO; UNCLASSIFIED DRUG; VACCINE;

ADULT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; ATTENUATION; CLINICAL ARTICLE; CLINICAL TRIAL; COCAINE DEPENDENCE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DIARRHEA; DRUG CONJUGATION; DRUG EFFICACY; DRUG ERUPTION; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG SCREENING; DRUG TOLERABILITY; EDEMA; ERYTHEMA; EUPHORIA; FEMALE; FOLLOW UP; HUMAN; IMMUNOGENICITY; INJECTION; INJECTION SITE REACTION; LARYNX DISORDER; MALAISE; MALE; MUSCLE TWITCH; MYALGIA; NAUSEA; NOSE CONGESTION; PAIN; PHARYNX DISEASE; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PRURITUS; RELAPSE; RHINITIS; RHINORRHEA; SIDE EFFECT; SNEEZING; URINALYSIS; VACCINATION; VISUAL DISORDER; VOMITING;

ADULT; ANTIBODIES; COCAINE; COCAINE-RELATED DISORDERS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; HUMANS; IMMUNIZATION SCHEDULE; MALE; MIDDLE AGED; VACCINATION; VACCINES;

EID: 22444437907     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2005.04.032     Document Type: Article

References (28)

1. G.N. Carmona, C.W. Schindler, M. Shoaib, R. Jufer, E.J. Cone, S.R. Goldberg Attenuation of cocaine-induced locomotor activity by butyrylcholinesterase Exp Clin Psychopharmacol 6 3 1998 274 279
2. M.R. Carrera, J.A. Ashley, L.H. Parsons, P. Wirsching, G.F. Koob, K.D. Janda Suppression of psychoactive effects of cocaine by active immunization Nature 378 1995 727 730
3. M.R.A. Carrera, J.A. Ashley, B. Zhou, P. Wirsching, G.F. Koob, K.D. Janda Cocaine vaccines: Antibody protection against relapse in a rat model Proc Natl Acad Sci 97 11 2000 6202 6206
4. K.M. Carroll, B.J. Rounsaville, L.T. Gordon, C. Nich, P. Jatlow, R.M. Bisighini Psychotherapy and pharmacotherapy for ambulatory cocaine users Arch Gen Psychiatry 51 1994 177 187
5. K.M. Carroll, B.J. Rounsaville, C. Nich, L.T. Gordon, P.W. Wirtz, F.H. Gawin One year follow-up of psychotherapy and pharmacotherapy for cocaine dependence: Delayed emergence of psychotherapy effects Arch Gen Psychiatry 51 1994 989 997
6. M.S. de Lima, B.G. de Oliveira Soares, A.A. Reisser, M. Farrell Pharmacological treatment of cocaine dependence: A systematic review Addiction 97 8 2002 931 949
7. European Agency for the Evaluation of Medicinal Products: Committee for Proprietary Medicinal Products (1997): Note for Guidance on Preclinical Pharmacological and Toxicological Testing of Vaccines. CPMP/SWP/465/95. Accessed at http://www.emea.eu.int/.
8. B.S. Fox Development of a therapeutic vaccine for the treatment of cocaine addiction Drug Alcohol Depend 48 1997 153 158
9. B.S. Fox, K.M. Kantak, M.A. Edwards, K.M. Black, B.K. Bollinger, A.J. Botka Efficacy of a therapeutic cocaine vaccine in rodent models Nature Med 2 1996 1129 1132
10. F.H. Gawin, H.D. Kleber Cocaine abuse treatment: An open pilot trial with lithium and desipramine Arch Gen Psychiatry 41 1984 903 909
11. F.H. Gawin, H.D. Kleber Abstinence symptomatology and psychiatric diagnosis in cocaine abusers: Clinical observations Arch Gen Psychiatry 43 1986 107 113
12. D.A. Gorelick Enhancing cocaine metabolism with butyrylcholinesterase as a treatment strategy Drug Alcohol Depend 48 3 1997 159 165
13. J.D. Grabenstein ImmunoFacts: Vaccines and Immunological Drugs St. Louis: Facts and Comparisons, Inc. 1994 p 487b
14. J. Holmgren, C. Czerkinsky, N. Lycke, A.M. Svennerholm Strategies for the induction of immune responses at mucosal surfaces making use of cholera toxin B subunit as immunogen, carrier, and adjuvant Am J Trop Med Hyg 50 1994 42 54
15. M. Jertborn, A.-M. Svennerholm, J. Holmgren Safety and immunogenicity of an oral recombinant cholera B subunit-whole cell vaccine in Swedish volunteers Vaccine 10 2 1992 130 132
16. M. Jertborn, A.-M. Svennerholm, J. Holmgren Immunological memory after immunization with oral cholera B subunit-whole-cell vaccine in Swedish volunteers Vaccine 12 1994 1078 1082
17. Kosten TR, Ciraulo DA (in press): Cocaine and psychostimulants. In: Kranzler HR, Ciraulo DA, editors. Clinical Manual of Addiction Psychopharmacology, Washington, DC: APPI Press.
18. Kosten TR, Rosen M, Bond J, Settles M, St. Clair Roberts J, Shields J, et al (2002): Human therapeutic cocaine vaccine: Safety and immunogenicity. Vaccine 20:1196-1204.
19. National Survey on Drug Abuse and Health. http://www.oas.samhsa.gov/ nhsdg.gov.
20. NIDA info facts: Science based facts on drug abuse and addiction. Revised November 2004. http://www.nida.nih.gov/Infofacts/Infofaxindex.html.
21. K. Silverman, S.T. Higgins, R.K. Brooner, I.D. Montoya, E.J. Cone, C.R. Schuster, K.L. Preston Sustained cocaine abstinence in methadone maintenance subjects through voucher based reinforcement therapy Arch Gen Psychiatry 53 1996 409 415
22. M. Stitzer, M.Y. Iguchi, L.J. Felch Contingency take-home incentive: Effects on drug use of methadone maintenance subjects J Consult Clin Psychol 60 1992 927 934
23. Substance Abuse and Mental Health Services Administration (2003): Year-End 2003 Emergency Department Data from the Drug Abuse Warning Network (DAWN). Office of Applied Studies. Rockville: MD. http://dawninfo.samhsa.gov. Accessed on March 15, 2005.
24. A. Svennerholm, L. Gothefors, D. Sack, P. Bardhan, J. Holmgren Local and systemic antibody responses and immunological memory after immunization with cholera B subunit by different routes Bull World Health Organ 62 1984 909 918
25. J.M. Swanson, N.D. Volkow Pharmacokinetic and pharmacodynamic properties of stimulants: Implications for the design of new treatments for ADHD Beh Brain Res 130 1 2002 73 78
26. N.D. Volkow, J.S. Fowler, G.J. Wang Imaging studies on the role of dopamine in cocaine reinforcement and addiction in humans J Psychopharmacol 13 4 1999 337 345
27. N.D. Volkow, G.J. Wang, M.W. Fischman, R.W. Foltin, J.S. Fowler, N.N. Abumrad Relationship between subjective effects of cocaine and dopamine transporter occupancy Nature 386 6627 1997 827 830
28. N.D. Volkow, G.J. Wang, S.J. Gatley, J.S. Fowler, Y.S. Ding, J. Logan Temporal relationships between the pharmacokinetics of methylphenidate in the human brain and its behavioral and cardiovascular effects Psychopharmacology (Berl) 123 1 1996 26 33