Differential Plasma MicroRNA Profiles in HBeAg Positive and HBeAg Negative Children with Chronic Hepatitis B

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Winther, Thilde Nordmann ^a   Bang Berthelsen, Claus Heiner ^a   Heiberg, Ida Louise ^a   Pociot, Flemming ^a   Hogh, Birthe ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B(E) ANTIGEN; MICRORNA; VIRUS DNA; VIRUS RNA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; UPREGULATION; VIRUS LOAD;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DNA, VIRAL; FEMALE; HEPATITIS B E ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; INFANT; LIVER; MALE; MICRORNAS; POLYMERASE CHAIN REACTION;

EID: 84874585466     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058236     Document Type: Article

References (43)

1. WHO website (2012) Hepatitis B. World Health Organization fact sheet 204. Available: http://www.who.int/mediacentre/factsheets/fs204/en/Accessed 2012 Jun 20.
2. McMahon BJ, Alward WL, Hall DB, Heyward WL, Bender TR, et al. (1985) Acute hepatitis B virus infection: relation of age to the clinical expression of disease and subsequent development of the carrier state. J Infect Dis 151: 599-603.
3. Tassopoulos NC, Papaevangelou GJ, Sjogren MH, Roumeliotou-Karayannis A, Gerin JL, et al. (1987) Natural history of acute hepatitis B surface antigen-positive hepatitis in Greek adults. Gastroenterology 92: 1844-1850.
4. McMahon BJ, (2009) The natural history of chronic hepatitis B virus infection. Hepatology 49: S45-55.
5. Lok AS, Heathcote EJ, Hoofnagle JH, (2001) Management of hepatitis B: 2000-summary of a workshop. Gastroenterology 120: 1828-1853.
6. Hoofnagle JH, Doo E, Liang TJ, Fleischer R, Lok AS, (2007) Management of hepatitis B: summary of a clinical research workshop. Hepatology 45: 1056-1075.
7. Chang MH, Hsu HY, Hsu HC, Ni YH, Chen JS, et al. (1995) The significance of spontaneous hepatitis B e antigen seroconversion in childhood: with special emphasis on the clearance of hepatitis B e antigen before 3 years of age. Hepatology 22: 1387-1392.
8. Chen CJ, Yang HI, Su J, Jen CL, You SL, et al. (2006) Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 295: 65-73.
9. Ni YH, Chang MH, Chen PJ, Tsai KS, Hsu HY, et al. (2007) Viremia profiles in children with chronic hepatitis B virus infection and spontaneous e antigen seroconversion. Gastroenterology 132: 2340-2345.
10. Iloeje UH, Yang HI, Chen CJ (2012) Natural history of chronic hepatitis B: what exactly has REVEAL Revealed? Liver Int.
11. Simonetti J, Bulkow L, McMahon BJ, Homan C, Snowball M, et al. (2010) Clearance of hepatitis B surface antigen and risk of hepatocellular carcinoma in a cohort chronically infected with hepatitis B virus. Hepatology 51: 1531-1537.
12. Paganelli M, Stephenne X, Sokal EM (2012) Chronic hepatitis B in children and adolescents. J Hepatol.
13. Esteller M, (2011) Non-coding RNAs in human disease. Nat Rev Genet 12: 861-874.
14. O'Connell RM, Rao DS, Chaudhuri AA, Baltimore D, (2010) Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol 10: 111-122.
15. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, et al. (2008) Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 105: 10513-10518.
16. Elmen J, Lindow M, Schutz S, Lawrence M, Petri A, et al. (2008) LNA-mediated microRNA silencing in non-human primates. Nature 452: 896-899.
17. Xiao C, Rajewsky K, (2009) MicroRNA control in the immune system: basic principles. Cell 136: 26-36.
18. Lecellier CH, Dunoyer P, Arar K, Lehmann-Che J, Eyquem S, et al. (2005) A cellular microRNA mediates antiviral defense in human cells. Science 308: 557-560.
19. Cullen BR, (2011) Viruses and microRNAs: RISCy interactions with serious consequences. Genes Dev 25: 1881-1894.
20. Zhang X, Zhang E, Ma Z, Pei R, Jiang M, et al. (2011) Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1. Hepatology 53: 1476-1485.
21. Guo H, Liu H, Mitchelson K, Rao H, Luo M, et al. (2011) MicroRNAs-372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B. Hepatology 54: 808-819.
22. Wang S, Qiu L, Yan X, Jin W, Wang Y, et al. (2012) Loss of microRNA 122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G(1)-modulated P53 activity. Hepatology 55: 730-741.
23. Waidmann O, Bihrer V, Pleli T, Farnik H, Berger A, et al. (2012) Serum microRNA-122 levels in different groups of patients with chronic hepatitis B virus infection. J Viral Hepat 19: e58-65.
24. Qi P, Cheng SQ, Wang H, Li N, Chen YF, et al. (2011) Serum microRNAs as biomarkers for hepatocellular carcinoma in Chinese patients with chronic hepatitis B virus infection. PLoS One 6: e28486.
25. Li LM, Hu ZB, Zhou ZX, Chen X, Liu FY, et al. (2010) Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma. Cancer Res 70: 9798-9807.
26. Haber BA, Block JM, Jonas MM, Karpen SJ, London WT, et al. (2009) Recommendations for screening, monitoring, and referral of pediatric chronic hepatitis B. Pediatrics. 124: e1007-1013.
27. SSI Statens Serum Institut, Copenhagen, Denmark website. Childhood vaccination programme in Denmark. Available: http://www.sst.dk/English/Infectious_diseases_and_vaccines/Vaccines/Childhood_vaccination_programme_in_DK.aspx Accessed 2012 June 20.
28. Mukaide M, Tanaka Y, Katayose S, Tano H, Murata M, et al. (2003) Development of real-time detection direct test for hepatitis B virus and comparison with two commercial tests using the WHO international standard. J Gastroenterol Hepatol 18: 1264-1271.
29. Krarup HB, Andersen S, Madsen PH, Okkels H, Hvingel BH, et al. (2008) Benign course of long-standing hepatitis B virus infection among Greenland Inuit? Scand J Gastroenterol 43: 334-343.
30. Jensen SG, Lamy P, Rasmussen MH, Ostenfeld MS, Dyrskjot L, et al. (2011) Evaluation of two commercial global miRNA expression profiling platforms for detection of less abundant miRNAs. BMC Genomics 12: 435.
31. Ng EK, Chong WW, Jin H, Lam EK, Shin VY, et al. (2009) Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 58: 1375-1381.
32. Ai J, Zhang R, Li Y, Pu J, Lu Y, et al. (2010) Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction. Biochem Biophys Res Commun 391: 73-77.
33. Zhu HT, Dong QZ, Wang G, Zhou HJ, Ren N, et al. (2012) Identification of suitable reference genes for qRT-PCR analysis of circulating microRNAs in hepatitis B virus-infected patients. Mol Biotechnol 50: 49-56.
34. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034.
35. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
36. Zhou J, Yu L, Gao X, Hu J, Wang J, et al. (2011) Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma. J Clin Oncol 29: 4781-4788.
37. Ji F, Yang B, Peng X, Ding H, You H, et al. (2011) Circulating microRNAs in hepatitis B virus-infected patients. J Viral Hepat 18: e242-251.
38. Bala S, Petrasek J, Mundkur S, Catalano D, Levin I, et al. (2012) Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced and inflammatory liver diseases. Hepatology.
39. Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, et al. (2007) A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129: 1401-1414.
40. Kosaka N, Iguchi H, Yoshioka Y, Takeshita F, Matsuki Y, et al. (2010) Secretory mechanisms and intercellular transfer of microRNAs in living cells. J Biol Chem 285: 17442-17452.
41. Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, et al. (2007) Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 9: 654-659.
42. Casalini P, Iorio MV, (2009) MicroRNAs and future therapeutic applications in cancer. J BUON 14 (Suppl 1): S17-22.
43. Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, et al. (2010) Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327: 198-201.